Wingham, J. orcid.org/0000-0002-8331-9206, Ahmed, I., Islam, M.T. et al. (2 more authors) (2022) Tailored additives for incorporation of antibacterial functionality into laser sintered parts. Frontiers in Biomaterials Science, 1. 929006.
Abstract
Infectious disease is a major cause of death worldwide, and novel methods capable of controlling the spread of disease are in high demand. This research presents a method of producing antimicrobial microcomposites by exploiting the powder-based nature of the Laser Sintering Additive Manufacturing process, via the incorporation of silver-containing additives. Silver phosphate glass additives in different formulations were designed to determine the effect of dissolution rate on the antimicrobial efficacy. These were characterised and successfully incorporated into polyamide 12 parts, without affecting the mechanical properties. The printed microcomposite parts displayed both bactericidal and antibiofouling effects against Gram-positive and Gram-negative bacteria in nutrient-poor conditions, with the efficacy found to be more sensitive to silver content than degradation rate.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2022 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
Keywords: | additive manufacturing; antibacterial material; microcomposite; phosphate glass; polymer laser sintering |
Dates: |
|
Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Mechanical Engineering (Sheffield) |
Funding Information: | Funder Grant number Engineering and Physical Sciences Research Council 1949272 |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 13 Jul 2022 10:21 |
Last Modified: | 13 Jul 2022 10:21 |
Status: | Published |
Publisher: | Frontiers Media S.A. |
Refereed: | Yes |
Identification Number: | 10.3389/fbiom.2022.929006 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:189044 |