Harrington, Marcus Oliver, Ngo, Hong-Viet and Cairney, Scott Ashley orcid.org/0000-0002-1135-6059 (2021) No benefit of auditory closed-loop stimulation on memory for semantically-incongruent associations. Neurobiology of learning and memory. 107482. ISSN 1095-9564
Abstract
Auditory closed-loop stimulation has gained traction in recent years as a means of enhancing slow oscillatory activity and, consequently, sleep-associated memory consolidation. Previous studies on this topic have primarily focused on the consolidation of semantically-congruent associations. In this study, we investigated the effect of auditory closed-loop stimulation on the overnight retention of semantically-incongruent associations. Twelve healthy males (age: M=20.06, SD=2.02 years) participated in two experimental conditions (simulation and sham). In the stimulation condition, clicks were delivered in phase with slow oscillation up-states, whereas in the sham condition no auditory stimuli were applied. Corroborating earlier work, stimulation (vs. sham) enhanced the slow oscillation rhythm, phase-coupled spindle activity and slow oscillation power. However, there was no benefit of stimulation on overnight memory retention. These findings suggest that closed-loop stimulation does not benefit semantically-incongruent associations.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2021 Elsevier Inc. All rights reserved. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Psychology (York) |
Funding Information: | Funder Grant number MEDICAL RESEARCH COUNCIL (MRC) MR/P020208/1 |
Depositing User: | Pure (York) |
Date Deposited: | 23 Jun 2021 07:50 |
Last Modified: | 19 Mar 2025 00:10 |
Published Version: | https://doi.org/10.1016/j.nlm.2021.107482 |
Status: | Published online |
Refereed: | Yes |
Identification Number: | 10.1016/j.nlm.2021.107482 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:175514 |
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