García-Vázquez, V., Hoteite, L., Lakeland, C.P. et al. (2 more authors) (2021) A Pd-catalyzed [4 + 2] annulation approach to fluorinated N-heterocycles. Organic Letters, 23 (7). pp. 2811-2815. ISSN 1523-7060
Abstract
3-Fluoro- and trifluoromethylthio-piperidines represent important building blocks for discovery chemistry. We report a simple and efficient method to access analogs of these compounds that are armed with rich functionality allowing them to be chemoselectively derivatized with high diastereocontrol.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2021 American Chemical Society. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 27 Apr 2021 10:49 |
Last Modified: | 27 Apr 2021 10:49 |
Status: | Published |
Publisher: | American Chemical Society (ACS) |
Refereed: | Yes |
Identification Number: | 10.1021/acs.orglett.1c00752 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:173483 |
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Filename: A Pd-Catalyzed [4 + 2] Annulation Approach to Fluorinated N-Heterocycles.pdf
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