Yan, J, Moreau, A, Khodaparast, S et al. (9 more authors) (2018) Bacterial Biofilm Material Properties Enable Removal and Transfer by Capillary Peeling. Advanced Materials, 30 (46). 1804153. ISSN 0935-9648
Abstract
Biofilms, surface‐attached communities of bacterial cells, are a concern in health and in industrial operations because of persistent infections, clogging of flows, and surface fouling. Extracellular matrices provide mechanical protection to biofilm‐dwelling cells as well as protection from chemical insults, including antibiotics. Understanding how biofilm material properties arise from constituent matrix components and how these properties change in different environments is crucial for designing biofilm removal strategies. Here, using rheological characterization and surface analyses of Vibrio cholerae biofilms, it is discovered how extracellular polysaccharides, proteins, and cells function together to define biofilm mechanical and interfacial properties. Using insight gained from our measurements, a facile capillary peeling technology is developed to remove biofilms from surfaces or to transfer intact biofilms from one surface to another. It is shown that the findings are applicable to other biofilm‐forming bacterial species and to multiple surfaces. Thus, the technology and the understanding that have been developed could potentially be employed to characterize and/or treat biofilm‐related infections and industrial biofouling problems.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. This is the peer reviewed version of the following article: Yan, J., Moreau, A., Khodaparast, S., Perazzo, A., Feng, J., Fei, C., Mao, S., Mukherjee, S., Košmrlj, A., Wingreen, N. S., Bassler, B. L., Stone, H. A., Adv. Mater. 2018, 30, 1804153. https://doi.org/10.1002/adma.201804153 , which has been published in final form at https://doi.org/10.1002/adma.201804153. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | adhesion energy; antibiotics; biofilms; fracture; rheology |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Mechanical Engineering (Leeds) > Institute of Engineering Thermofluids, Surfaces & Interfaces (iETSI) (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 11 Mar 2020 12:02 |
Last Modified: | 13 Mar 2020 02:55 |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1002/adma.201804153 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:158297 |
Commentary/Response Threads
- Yan, J, Moreau, A, Khodaparast, S, Perazzo, A, Feng, J, Fei, C, Mao, S, Mukherjee, S, Košmrlj, A, Wingreen, NS, Bassler, BL and Stone, HA Bacterial Biofilm Material Properties Enable Removal and Transfer by Capillary Peeling. (deposited 11 Mar 2020 12:02) [Currently Displayed]