Manson, JA orcid.org/0000-0001-7392-3197, Clayton, AD orcid.org/0000-0002-4634-8008, Gonzalez Niño, C et al. (5 more authors) (2019) A Hybridised Optimisation of an Automated Photochemical Continuous Flow Reactor. Chimia, 73 (10). pp. 817-822. ISSN 0009-4293
Abstract
A new hybridized algorithm that combines process optimisation with response surface mapping was developed and applied in an automated continuous flow reaction. Moreover, a photochemical cascade CSTR was developed and characterised by chemical actinometry, showing photon flux density of ten times greater than previously reported in batch. The success of the algorithm was then evaluated in the aerobic oxidation of sp3 C–H bonds using benzophenone as photosensitizer in the newly developed photo reactor.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © Swiss Chemical Society. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Algorithm; automation; continuous flow; photochemistry; self-optimisation |
Dates: |
|
Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemical & Process Engineering (Leeds) The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Inorganic Chemistry (Leeds) The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds) The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Mechanical Engineering (Leeds) > Institute of Engineering Thermofluids, Surfaces & Interfaces (iETSI) (Leeds) |
Funding Information: | Funder Grant number EPSRC EP/R032807/1 BBSRC BIOCATNET PoC-013 ACS Green Chemistry Institute Not Known |
Depositing User: | Symplectic Publications |
Date Deposited: | 18 Sep 2019 10:10 |
Last Modified: | 01 Oct 2020 00:38 |
Status: | Published |
Publisher: | Schweizerische Chemische Gedellschaft (Swiss Chemistry Society) |
Identification Number: | 10.2533/chimia.2019.817 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:150953 |