Tarn, Mark D., Kızılyer, Nuray Yavuzkanat, Esfahani, Mohammad M.N. et al. (5 more authors) (2018) Plastic Scintillator-Based Microfluidic Devices for Miniaturized Detection of Positron Emission Tomography Radiopharmaceuticals. Chemistry - A European Journal. pp. 13749-13753. ISSN: 0947-6539
Abstract
A miniaturized radio-HPLC detector has been developed comprising a microfluidic device fabricated from plastic scintillator in combination with a silicon photomultiplier light sensor, and tested with samples containing a positron-emitting radionuclide, [18F]fluoride. This cost-effective, small footprint analytical tool is ideal for incorporation into integrated quality control systems for the testing of positron emission tomography (PET) radiopharmaceuticals to good manufacturing practice (GMP) standards.
Metadata
| Item Type: | Article |
|---|---|
| Authors/Creators: |
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| Copyright, Publisher and Additional Information: | © 2018, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details. |
| Keywords: | liquid chromatography,microfluidics,plastic scintillator,positron emission tomography,radiopharmaceuticals,silicon photomultiplier |
| Dates: |
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| Institution: | The University of York |
| Academic Units: | The University of York > Faculty of Sciences (York) > Physics (York) |
| Depositing User: | Pure (York) |
| Date Deposited: | 22 Jan 2019 09:40 |
| Last Modified: | 20 Sep 2025 00:43 |
| Published Version: | https://doi.org/10.1002/chem.201802395 |
| Status: | Published |
| Refereed: | Yes |
| Identification Number: | 10.1002/chem.201802395 |
| Related URLs: | |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:141363 |
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Description: Tarn et al 2018 Chem Eur J

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