Tarn, Mark D., Kızılyer, Nuray Yavuzkanat, Esfahani, Mohammad M.N. et al. (5 more authors) (2018) Plastic Scintillator-Based Microfluidic Devices for Miniaturized Detection of Positron Emission Tomography Radiopharmaceuticals. Chemistry - A European Journal. pp. 13749-13753. ISSN 1521-3765
Abstract
A miniaturized radio-HPLC detector has been developed comprising a microfluidic device fabricated from plastic scintillator in combination with a silicon photomultiplier light sensor, and tested with samples containing a positron-emitting radionuclide, [18F]fluoride. This cost-effective, small footprint analytical tool is ideal for incorporation into integrated quality control systems for the testing of positron emission tomography (PET) radiopharmaceuticals to good manufacturing practice (GMP) standards.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details. |
Keywords: | liquid chromatography,microfluidics,plastic scintillator,positron emission tomography,radiopharmaceuticals,silicon photomultiplier |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Physics (York) |
Depositing User: | Pure (York) |
Date Deposited: | 22 Jan 2019 09:40 |
Last Modified: | 16 Oct 2024 15:12 |
Published Version: | https://doi.org/10.1002/chem.201802395 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1002/chem.201802395 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:141363 |
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