Duckett, Simon orcid.org/0000-0002-9788-6615, Fekete, Marianna orcid.org/0000-0003-4869-0912, Nelson-Forde, Rhianna et al. (5 more authors) (2018) Harnessing asymmetric N-heterocyclic carbene ligands to optimise SABRE hyperpolarisation. Catalysis Science and Technology. CY-ART-06-2018-001214.R1. ISSN 2044-4761
Abstract
The catalytic signal amplification process has become widely used for the hyperpolarisation of small molecules to improve their magnetic resonance detectability. It harnesses the latent polarisation of parahydrogen, and involves the formation of labile metal complex that often contains an N-heterocyclic carbene (NHC) ligand (e.g. [Ir(H)2(NHC)(pyridine)3]Cl), which act as a polarisation transfer catalyst. Unfortunately, if the target molecule is too bulky, binding to the catalyst is poor and the hyperpolarisation yield is therefore low. We illustrate here the behaviour of a series of asymmetric NHC containing catalysts towards 3,4- and 3,5-lutidine in order to show how catalyst design can be used to dramatically improve the outcome of this catalytic process for sterically encumbered ligands.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 23 Jul 2018 09:10 |
Last Modified: | 26 Nov 2024 00:39 |
Published Version: | https://doi.org/10.1039/C8CY01214H |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1039/C8CY01214H |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:133663 |