Raxworthy, MJ orcid.org/0000-0002-6206-6748, Serino, LP and Iddon, PD (2018) Electrospun bioresorbable tissue repair scaffolds: From laboratory to clinic. In: 2018 3rd Biennial South African Biomedical Engineering Conference, SAIBMEC 2018. 3rd South African Biomedical Engineering Conference, 04-06 Apr 2018, Stellenbosch, South Africa. IEEE ISBN 9781538625163
Abstract
The healing of soft tissue wounds and injury sites is a complex process requiring the participation of many different cells, tissues, proteins and tissue components in a coordinated manner. We describe the development of regenerative, electrospun, bioresorbable advanced material tissue scaffolds providing three dimensional (3D) structure for cells involved in the repair of soft tissue injuries. One product, EktoTherix™ provides a micron-scale 3D architecture to enhance the recruitment of reparative cells onto this temporary support and in this way the body's capacity to repair itself is utilised. EktoTherix and other electrospun tissue scaffolds have been translated from early stage laboratory work through manufacturing process development and clinical investigation.
Metadata
Item Type: | Proceedings Paper |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018, IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. |
Keywords: | electrospinning, scaffold, tissue repair, medical device translation, bioresorbable polymer |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Mechanical Engineering (Leeds) > Institute of Medical and Biological Engineering (iMBE) (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 27 Jun 2018 16:16 |
Last Modified: | 27 Jun 2018 16:16 |
Status: | Published |
Publisher: | IEEE |
Identification Number: | 10.1109/SAIBMEC.2018.8363177 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:132600 |