Clarke, Aimee K., Unsworth, William P. orcid.org/0000-0002-9169-5156 and Taylor, Richard J.K. orcid.org/0000-0002-5880-2490 (2018) Divergent reactivity of phenol- and anisole-tethered donor-acceptor α-diazoketones. Tetrahedron. ISSN 0040-4020
Abstract
The first study of the divergent reactivity of phenol/anisole-tethered donor-acceptor α-diazoketones is described. Four distinct product classes were shown to be accessible from closely related α-diazoketone precursors, with the reaction outcome dependent on the nature of the oxygen substituent on the phenol/anisole ring and the catalyst used to decompose the diazo group. Anisole and TBS-protected derivatives selectively produce three products types (cyclopropanes, tetralones and 1,2-dicarbonyls) while phenols selectively produce spirocyclic dienones.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © Elsevier, 2018. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. |
Keywords: | Anisole,Buchner reaction,Divergent reactivity,Phenol,α-Diazocarbonyl compounds |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 18 Apr 2018 08:40 |
Last Modified: | 16 Oct 2024 14:38 |
Published Version: | https://doi.org/10.1016/j.tet.2018.02.003 |
Status: | Published online |
Refereed: | Yes |
Identification Number: | 10.1016/j.tet.2018.02.003 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:129800 |
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