Norcott, Philip orcid.org/0000-0003-4082-2079, Burns, Michael J. orcid.org/0000-0002-5569-1270, Rayner, Peter J. orcid.org/0000-0002-6577-4117 et al. (2 more authors) (2018) Using 2H Labelling to Improve the NMR detectability of a Series of Pyridines by SABRE. MAGNETIC RESONANCE IN CHEMISTRY. ISSN 0749-1581
Abstract
By introducing a range of 2H labels into pyridine and the para-substituted agents methyl isonicotinate and isonicotinamide we significantly improve their NMR detectability in conjunction with the Signal Amplification by Reversible Exchange (SABRE) process. We describe how the rates of T1 relaxation for the remaining 1H nuclei are increased and show how this leads to a concomitant increase in the level of 1H and 13C hyperpolarization that can ultimately be detected.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | .This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details |
Dates: |
|
Institution: | The University of York |
Academic Units: | The University of York The University of York > Faculty of Sciences (York) > Chemistry (York) |
Funding Information: | Funder Grant number WELLCOME TRUST 098335/Z/12/Z |
Depositing User: | Pure (York) |
Date Deposited: | 03 Jan 2018 10:20 |
Last Modified: | 07 Feb 2025 00:18 |
Published Version: | https://doi.org/10.1002/mrc.4703 |
Status: | Published online |
Refereed: | Yes |
Identification Number: | 10.1002/mrc.4703 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:125745 |
Downloads
Filename: MRC_revision_final_Changes_Accepted.pdf
Description: MRC_revision_final_Changes Accepted
Filename: Norcott_et_al_2018_Magnetic_Resonance_in_Chemistry.pdf
Description: Norcott_et_al-2018-Magnetic_Resonance_in_Chemistry
Licence: CC-BY 2.5