Sharma, SS orcid.org/0000-0001-9465-8978, Greenwood, DC orcid.org/0000-0001-7035-3096, Simpson, NAB orcid.org/0000-0002-0758-7583 et al. (1 more author) (2018) Is dietary macronutrient composition during pregnancy associated with offspring birth weight? An observational study. British Journal of Nutrition, 119 (3). pp. 330-339. ISSN 0007-1145
Abstract
There is lack of evidence on the differential impact of maternal macronutrient consumption: carbohydrates (CHO), fats and protein on birth weight. We investigated the association between maternal dietary macronutrient intakes and their sub-components such as saccharides and fatty acids and birth weight. This analyses included 1,196 women with singleton pregnancies who were part of the CAffeine and REproductive health study in Leeds, UK between 2003 and 2006. Women were interviewed in each trimester. Dietary information was collected twice using a 24-h dietary recall about 8–12 weeks and 13–27 weeks of gestation. Multiple linear regression models adjusted for alcohol and smoking in trimester 1, showed that each additional 10 g/d CHO consumption was associated with an increase of 4 g (95 % CI 1, 7; P=0·003) in birth weight. Conversely, an additional 10 g/d fat intake was associated with a lower birth weight of 8 g (95 % CI 0, 16; P=0·04) when we accounted for energy contributing macronutrients in each model, and maternal height, weight, parity, ethnicity, gestational age at delivery and sex of the baby. There was no evidence of an association between protein intake and birth weight. Maternal diet in trimester 2 suggested that higher intakes of glucose (10 g/d) and lactose (1 g/d) were both associated with higher birth weight of 52 g (95 % CI 4, 100; P=0·03) and 5 g (95 % CI 2, 7; P<0·001) respectively. These results show that dietary macronutrient composition during pregnancy is associated with birth weight outcomes. An appropriately balanced intake of dietary CHO and fat during pregnancy could support optimum birth weight.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Authors 2018. This article has been published in a revised form in British Journal of Nutrition [https://doi.org/10.1017/S0007114517003609]. This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Macronutrients; Protein; Carbohydrates; Fat; Birth weight; Birth Centiles; Pregnancy; Diet |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Inst of Biomed & Clin Sciences (LIBACS) (Leeds) > Obstetrics & Gynaecology (Leeds) |
Funding Information: | Funder Grant number Food Standards Agency T01033 |
Depositing User: | Symplectic Publications |
Date Deposited: | 23 Nov 2017 13:25 |
Last Modified: | 13 Apr 2018 08:29 |
Status: | Published |
Publisher: | Cambridge University Press |
Identification Number: | 10.1017/S0007114517003609 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:124379 |