Rossi-Ashton, James A, Taylor, Richard J K orcid.org/0000-0002-5880-2490 and Unsworth, William P orcid.org/0000-0002-9169-5156 (2017) Selective synthesis of three product classes from imine and carboxylic acid precursors via direct imine acylation. Organic and Biomolecular Chemistry. pp. 7527-7532. ISSN 1477-0539
Abstract
Three divergent Direct Imine Acylation (DIA) procedures are reported that allow the selective generation of δ-lactams, β-lactams and tetrahydropyrimidinones (via a novel three-component coupling) from imine and carboxylic acid precursors. All operate via initial N-acyliminium ion formation and diverge depending on the reaction conditions and nature of the substrates.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Royal Society of Chemistry 2017. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details |
Keywords: | Journal Article |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 07 Sep 2017 08:30 |
Last Modified: | 31 Mar 2025 23:06 |
Published Version: | https://doi.org/10.1039/c7ob02039b |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1039/c7ob02039b |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:120983 |
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