Hurst, Timothy E. orcid.org/0000-0003-0524-2909 and Taylor, Richard J.K. orcid.org/0000-0002-5880-2490
(2017)
A Cu-Catalysed Radical Cross-Dehydrogenative Coupling Approach to Acridanes and Related Heterocycles.
European Journal of Organic Chemistry.
pp. 203-207.
ISSN 1099-0690
Abstract
The synthesis of acridanes and related compounds through a Cu-catalysed radical cross-dehydrogenative coupling of simple 2-[2-(arylamino)aryl]malonates is reported. This method can be further streamlined to a one-pot protocol involving the in situ fomation of the 2-[2-(arylamino)aryl]malonate by α-arylation of diethyl malonate with 2-bromodiarylamines under Pd catalysis, followed by Cu-catalysed cyclisation.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2017 Wiley-VCH Verlag GmbH & Co. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details |
Keywords: | Acridanes,Copper,Cross-coupling,Dehydrogenation,Homogeneous catalysis,Nitrogen heterocycles,One-pot reaction |
Dates: |
|
Institution: | The University of York |
Academic Units: | The University of York The University of York > Faculty of Sciences (York) > Chemistry (York) |
Funding Information: | Funder Grant number EPSRC EP/J000124/1 |
Depositing User: | Pure (York) |
Date Deposited: | 30 Jan 2017 09:53 |
Last Modified: | 16 Oct 2024 13:31 |
Published Version: | https://doi.org/10.1002/ejoc.201601336 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1002/ejoc.201601336 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:111371 |
Download
Filename: Hurst_Taylor_Acridanes_EJOC_Revised.docx
Description: Hurst_Taylor_Acridanes_EJOC_Revised