The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS): An Update

Abstract

Gluten-related disorders have recently been reclassified with an emerging scientific literature supporting the concept of non-celiac gluten sensitivity (NCGS). New research has specifically addressed prevalence, immune mechanisms, the recognition of non-immunoglobulin E (non-IgE) wheat allergy and overlap of NCGS with irritable bowel syndrome (IBS)-type symptoms. This review article will provide clinicians with an update that directly impacts on the management of a subgroup of their IBS patients whose symptoms are triggered by wheat ingestion.

Metadata

Authors/Creators:	Catassi, C. Alaedini, A. Bojarski, C. Bonaz, B. Bouma, G. Carroccio, A. https://orcid.org/0000-0001-8913-7916 Castillejo, G. https://orcid.org/0000-0001-6737-075X De Magistris, L. Dieterich, W. Di Liberto, D. Elli, L. Fasano, A. Hadjivassiliou, M. https://orcid.org/0000-0003-2542-8954 Kurien, M. https://orcid.org/0000-0002-4227-9500 Lionetti, E. Mulder, C.J. Rostami, K. Sapone, A. Scherf, K. Schuppan, D. Trott, N. Volta, U. Zevallos, V. Zopf, Y. Sanders, D.S.
Copyright, Publisher and Additional Information:	© 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Keywords:	amylase-trypsin inhibitors (ATIs); celiac disease; gluten sensitivity; gluten-free diet; gluten-related disorders; wheat allergy
Dates:	Accepted: 17 November 2017 Published: 21 November 2017
Institution:	The University of Sheffield
Academic Units:	The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Infection, Immunity and Cardiovascular Disease The University of Sheffield > Sheffield Teaching Hospitals
Depositing User:	Symplectic Sheffield
Date Deposited:	28 Nov 2017 17:08
Last Modified:	28 Nov 2017 17:08
Published Version:	https://doi.org/10.3390/nu9111268
Status:	Published
Publisher:	MDPI
Refereed:	Yes
Identification Number:	https://doi.org/10.3390/nu9111268
Related URLs:	Author

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The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS): An Update

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