When is it Beneficial to Reject Improvements?

We investigate two popular trajectory-based algorithms from biology and physics to answer a question of general significance: when is it beneficial to reject improvements? A distinguishing factor of SSWM (Strong Selection Weak Mutation), a popular model from population genetics, compared to the Metropolis algorithm (MA), is that the former can reject improvements, while the latter always accepts them. We investigate when one strategy outperforms the other. Since we prove that both algorithms converge to the same stationary distribution, we concentrate on identifying a class of functions inducing large mixing times, where the algorithms will outperform each other over a long period of time. The outcome of the analysis is the definition of a function where SSWM is efficient, while Metropolis requires at least exponential time.