Items where authors include "de Silva, T.I."
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Liew, F., Efstathiou, C. orcid.org/0000-0001-6125-8126, Fontanella, S. et al. (1457 more authors) (2024) Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease. Nature Immunology, 25 (4). pp. 607-621. ISSN 1529-2908
Suau Sans, M. orcid.org/0000-0003-3607-0302, Manneh, M., Ceesay, I. et al. (7 more authors) (2024) Health-seeking behaviour and beliefs around sore throat in The Gambia: A qualitative study. PLOS Global Public Health, 4 (3). e0002257. ISSN 2767-3375
Neale, I. orcid.org/0000-0001-7026-7390, Ali, M. orcid.org/0000-0003-0170-7182, Kronsteiner, B. orcid.org/0000-0003-0867-2867 et al. (26 more authors) (2023) CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study. mBio, 14 (5). e0121223. ISSN 2161-2129
Armitage, E.P. orcid.org/0000-0003-1125-4260, Keeley, A.J. orcid.org/0000-0001-9386-1157, de Crombrugghe, G. orcid.org/0000-0003-4700-8600 et al. (13 more authors) (2023) Streptococcus pyogenes carriage acquisition, persistence and transmission dynamics within households in The Gambia (SpyCATS): protocol for a longitudinal household cohort study. Wellcome Open Research, 8. 41. ISSN 2398-502X
Keeley, A.J. orcid.org/0000-0001-9386-1157, Groves, D., Armitage, E.P. et al. (17 more authors) (2023) Streptococcus pyogenes colonization in children aged 24–59 months in the Gambia: impact of live attenuated influenza vaccine and associated serological responses. The Journal of Infectious Diseases, 228 (7). pp. 957-965. ISSN 0022-1899
Panca, M., Blackstone, J., Stirrup, O. et al. (24 more authors) (2023) Evaluating the cost implications of integrating SARS-CoV-2 genome sequencing for infection prevention and control investigation of nosocomial transmission within hospitals. Journal of Hospital Infection, 139. pp. 23-32. ISSN 0195-6701
Hornsby, H. orcid.org/0000-0002-6657-9743, Nicols, A.R. orcid.org/0000-0002-1813-3819, Longet, S. orcid.org/0000-0001-5026-431X et al. (40 more authors) (2023) Omicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history. Nature Communications, 14 (1). 5065. ISSN 2041-1723
Williams, D.M. orcid.org/0000-0001-8483-021X, Hornsby, H.R. orcid.org/0000-0002-6657-9743, Shehata, O.M. et al. (19 more authors) (2023) Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy. iScience, 26 (7). 107056. ISSN 2589-0042
Asante, I.A., Hsu, S.N., Boatemaa, L. et al. (17 more authors) (2023) Repurposing an integrated national influenza platform for genomic surveillance of SARS-CoV-2 in Ghana: a molecular epidemiological analysis. The Lancet Global Health, 11 (7). e1075-e1085. ISSN 2214-109X
Bah, S.Y., Kujabi, M.A., Darboe, S. orcid.org/0000-0002-4711-3307 et al. (9 more authors) (2023) Acquisition and carriage of genetically diverse multi-drug resistant gram-negative bacilli in hospitalised newborns in The Gambia. Communications Medicine, 3 (1). 79. ISSN 2730-664X
Dijokaite-Guraliuc, A., Das, R., Zhou, D. et al. (44 more authors) (2023) Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses. Cell Reports, 42 (4). 112271. ISSN 2211-1247
Moore, S.C. orcid.org/0000-0001-8610-2806, Kronsteiner, B., Longet, S. et al. (61 more authors) (2023) Evolution of long-term vaccine-induced and hybrid immunity in healthcare workers after different COVID-19 vaccine regimens. Med, 4 (3). 191-215.e9. ISSN 2666-6340
Kanteh, A., Jallow, H.S., Manneh, J. et al. (25 more authors) (2023) Genomic epidemiology of SARS-CoV-2 infections in The Gambia: an analysis of routinely collected surveillance data between March, 2020, and January, 2022. The Lancet Global Health, 11 (3). e414-e424. ISSN 2214-109X
Jarju, S. orcid.org/0000-0003-2621-8406, Senghore, E., Brotherton, H. et al. (19 more authors) (2023) Circulation of respiratory viruses during the COVID-19 pandemic in The Gambia [version 2; peer review: 2 approved]. Gates Open Research, 6. 148. ISSN 2572-4754
Turtle, L. orcid.org/0000-0002-0778-1693, Thorpe, M. orcid.org/0000-0003-1911-9581, Drake, T.M. et al. (16 more authors) (2023) Outcome of COVID-19 in hospitalised immunocompromised patients: an analysis of the WHO ISARIC CCP-UK prospective cohort study. PLOS Medicine, 20 (1). e1004086. ISSN 1549-1277
Huo, J., Dijokaite-Guraliuc, A., Liu, C. et al. (34 more authors) (2023) A delicate balance between antibody evasion and ACE2 affinity for Omicron BA.2.75. Cell Reports, 42 (1). 111903. ISSN 2211-1247
Armitage, E.P. orcid.org/0000-0003-1125-4260, Keeley, A.J. orcid.org/0000-0001-9386-1157, de Crombrugghe, G. orcid.org/0000-0003-4700-8600 et al. (13 more authors) (2023) Streptococcus pyogenes carriage acquisition, persistence and transmission dynamics within households in The Gambia (SpyCATS): protocol for a longitudinal household cohort study [version 1; peer review: awaiting peer review]. Wellcome Open Research, 8. 41. ISSN 2398-502X
Liew, F. orcid.org/0000-0002-8736-9198, Talwar, S., Cross, A. et al. (1439 more authors) (2023) SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination. eBioMedicine, 87. 104402. ISSN 2352-3964
Colton, H. orcid.org/0000-0002-3287-4103, Parker, M.D., Stirrup, O. et al. (18 more authors) (2023) Factors affecting turnaround time of SARS-CoV-2 sequencing for inpatient infection prevention and control decision making: analysis of data from the COG-UK HOCI study. Journal of Hospital Infection, 131. pp. 34-42. ISSN 0195-6701
Miller, P.D.E., Patel, S.R., Skinner, R. orcid.org/0000-0002-1162-675X et al. (9 more authors) (2023) Joint consensus statement on the vaccination of adult and paediatric haematopoietic stem cell transplant recipients: prepared on behalf of the British society of blood and marrow transplantation and cellular therapy (BSBMTCT), the Children's cancer and Leukaemia Group (CCLG), and British Infection Association (BIA). Journal of Infection, 86 (1). pp. 1-8. ISSN 0163-4453
Stirrup, O., Blackstone, J., Mapp, F. et al. (45 more authors) (2022) Effectiveness of rapid SARS-CoV-2 genome sequencing in supporting infection control for hospital-onset COVID-19 infection: multicenter, prospective study. eLife, 11. e78427. ISSN 2050-084X
Boswell, M.T., Nazziwa, J., Kuroki, K. et al. (14 more authors) (2022) Intrahost evolution of the HIV-2 capsid correlates with progression to AIDS. Virus Evolution, 8 (2). veac075. ISSN 2057-1577
Longet, S., Hargreaves, A., Healy, S. et al. (12 more authors) (2022) mRNA vaccination drives differential mucosal neutralizing antibody profiles in naïve and SARS-CoV-2 previously-infected individuals. Frontiers in Immunology, 13. 953949. ISSN 1664-3224
Sanyang, B., de Silva, T.I. orcid.org/0000-0002-6498-9212, Kanteh, A. et al. (7 more authors) (2022) Effect of intra-partum azithromycin on the development of the infant nasopharyngeal microbiota: a post hoc analysis of a double-blind randomized trial. eBioMedicine, 83. 104227. ISSN 2352-3964
Keeley, A.J., Carducci, M., Massai, L. et al. (4 more authors) (2022) Development and characterisation of a four-plex assay to measure Streptococcus pyogenes antigen-specific IgG in human sera. Methods and Protocols, 5 (4). 55. ISSN 2409-9279
Locke, T., Parsons, H., Briffa, N. et al. (3 more authors) (2022) A bundle of infection control measures reduces post-operative sternal wound infection due to Staphylococcus aureus but not Gram-negative bacteria : a retrospective analysis of 6,903 patient episodes. Journal of Hospital Infection, 126. pp. 21-28. ISSN 0195-6701
Parker, M.D., Stewart, H., Shehata, O.M. et al. (36 more authors) (2022) Altered subgenomic RNA abundance provides unique insight into SARS-CoV-2 B.1.1.7/Alpha variant infections. Communications Biology, 5. 666. ISSN 2399-3642
Colton, H. orcid.org/0000-0002-3287-4103, Hodgson, D., Hornsby, H. et al. (20 more authors) (2022) Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust. Wellcome Open Research, 6. 220.
Minter, A., Hoschler, K., Jagne, Y.J. et al. (7 more authors) (2022) Estimation of seasonal influenza attack rates and antibody dynamics in children using cross-sectional serological data. The Journal of Infectious Diseases, 225 (10). pp. 1750-1754. ISSN 0022-1899
Shankar, S., Beckett, J., Tipton, T. et al. (23 more authors) (2022) SARS-CoV-2-specific T cell responses are not associated with protection against reinfection in hemodialysis patients. Journal of the American Society of Nephrology, 33 (5). pp. 883-887. ISSN 1046-6673
Wright, D.W., Harvey, W.T., Hughes, J. et al. (13 more authors) (2022) Tracking SARS-CoV-2 mutations and variants through the COG-UK-Mutation Explorer. Virus Evolution, 8 (1). veac023. pp. 1-14.
Cencioni, M.T., Genchi, A., Brittain, G. orcid.org/0000-0002-9903-7203 et al. (6 more authors) (2022) Immune reconstitution following autologous hematopoietic stem cell transplantation for multiple sclerosis : a review on behalf of the EBMT autoimmune diseases working party. Frontiers in Immunology, 12. 813957.
Jagne, I., Keeley, A.J., Bojang, A. et al. (11 more authors) (2022) Impact of intra-partum azithromycin on carriage of group A streptococcus in the Gambia: a posthoc analysis of a double-blind randomized placebo-controlled trial. BMC Infectious Diseases, 22 (1). 103. ISSN 1471-2334
Costa-Martins, A.G., Mane, K., Lindsey, B.B. orcid.org/0000-0003-4227-2592 et al. (17 more authors) (2021) Prior upregulation of interferon pathways in the nasopharynx impacts viral shedding following live attenuated influenza vaccine challenge in children. Cell Reports Medicine, 2 (12). 100465. ISSN 2666-3791
Boshier, F.A.T., Venturini, C., Stirrup, O. et al. (42 more authors) (2021) The Alpha variant was not associated with excess nosocomial SARS-CoV-2 infection in a multi-centre UK hospital study. Journal of Infection, 83 (6). pp. 693-700. ISSN 0163-4453
Peno, C., Armitage, E.P., Clerc, M. et al. (15 more authors) (2021) The effect of live attenuated influenza vaccine on pneumococcal colonisation densities among children aged 24–59 months in The Gambia: a phase 4, open label, randomised, controlled trial. The Lancet Microbe, 2 (12). e656-e665. ISSN 2666-5247
Jeewandara, C., Jayathilaka, D., Ranasinghe, D. et al. (12 more authors) (2021) Genomic and epidemiological analysis of SARS-CoV-2 viruses in Sri Lanka. Frontiers in Microbiology, 12. 722838.
Colton, H. orcid.org/0000-0002-3287-4103, Greenfield, D.M. orcid.org/0000-0002-3733-2717, Snowden, J.A. orcid.org/0000-0001-6819-3476 et al. (6 more authors) (2021) Long-term survivors following autologous haematopoetic stem cell transplantation have significant defects in their humoral immunity against vaccine preventable diseases, years on from transplant. Vaccine, 39 (34). pp. 4778-4783. ISSN 0264-410X
Stirrup, O., Hughes, J., Parker, M. orcid.org/0000-0003-2999-3870 et al. (13 more authors) (2021) Rapid feedback on hospital onset SARS-CoV-2 infections combining epidemiological and sequencing data. eLife, 10. e65828.
Peto, L. orcid.org/0000-0002-4100-2163, Rodger, G., Carter, D.P. et al. (19 more authors) (2021) Diagnosis of SARS-CoV-2 infection with LamPORE, a high-throughput platform combining loop-mediated isothermal amplification and nanopore sequencing. Journal of Clinical Microbiology, 59 (6). e03271-20. ISSN 0095-1137
Williams, E.J., Mair, L., de Silva, T.I. orcid.org/0000-0002-6498-9212 et al. (7 more authors) (2021) Evaluation of procalcitonin as a contribution to antimicrobial stewardship in SARS-CoV-2 infection: a retrospective cohort study. Journal of Hospital Infection, 110. pp. 103-107. ISSN 0195-6701
ten-Caten, F., Gonzalez-Dias, P., Castro, Í. et al. (18 more authors) (2021) In-depth analysis of laboratory parameters reveals the interplay between sex, age, and systemic inflammation in individuals with COVID-19. International Journal of Infectious Diseases, 105. pp. 579-587. ISSN 1201-9712
Parker, M.D. orcid.org/0000-0003-2999-3870, Lindsey, B.B. orcid.org/0000-0003-4227-2592, Leary, S. et al. (30 more authors) (2021) Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data. Genome Research, 31 (4). pp. 645-658. ISSN 1088-9051
Colton, H., Ankcorn, M., Yavuz, M. et al. (9 more authors) (2021) Improved sensitivity using a dual target, E and RdRp assay for the diagnosis of SARS-CoV-2 infection : experience at a large NHS Foundation Trust in the UK. Journal of Infection, 82 (1). pp. 159-198. ISSN 0163-4453
Parker, M.D. orcid.org/0000-0003-2999-3870, Lindsey, B.B. orcid.org/0000-0003-4227-2592, Leary, S. et al. (29 more authors) (2020) periscope: sub-genomic RNA identification in SARS-CoV-2 genomic sequencing data. bioRxiv. (Submitted)
Korber, B., Fischer, W.M., Gnanakaran, S. et al. (36 more authors) (2020) Tracking changes in SARS-CoV-2 Spike: evidence that D614G increases infectivity of the COVID-19 virus. Cell, 182 (4). 812-827.e19. ISSN 0092-8674
Keeley, A.J. orcid.org/0000-0001-9386-1157, Evans, C.M. and de Silva, T.I. orcid.org/0000-0002-6498-9212 (2020) Asymptomatic SARS-CoV-2 infection: the tip or the iceberg? Thorax, 75 (8). pp. 621-622. ISSN 0040-6376
Williams, E.J. orcid.org/0000-0002-5612-610X, Mair, L. orcid.org/0000-0003-0446-1640, de Silva, T.I. orcid.org/0000-0002-6498-9212 et al. (7 more authors) (2020) Routine measurement of serum procalcitonin allows antibiotics to be safely withheld in patients admitted to hospital with SARS-CoV-2 infection. medRxiv. (Submitted)
Lindsey, B.B., Höschler, K. and de Silva, T.I. orcid.org/0000-0002-6498-9212 (2020) Complexities in predicting the immunogenicity of live attenuated influenza vaccines. Clinical Infectious Diseases, 70 (10). pp. 2235-2236. ISSN 1058-4838
Keeley, A.J., Evans, C., Colton, H. et al. (7 more authors) (2020) Roll-out of SARS-CoV-2 testing for healthcare workers at a large NHS foundation trust in the United Kingdom, March 2020. Eurosurveillance, 25 (14). ISSN 1560-7917
Mackenzie, G.A., Vilane, A., Salaudeen, R. et al. (9 more authors) (2019) Respiratory syncytial, parainfluenza and influenza virus infection in young children with acute lower respiratory infection in rural Gambia. Scientific Reports, 9 (1). 17965. ISSN 2045-2322
Armitage, E.P., Senghore, E., Darboe, S. et al. (9 more authors) (2019) High burden and seasonal variation of paediatric scabies and pyoderma prevalence in the Gambia : a cross-sectional study. PLOS Neglected Tropical Diseases, 13 (10). 0007801. ISSN 1935-2727
Darboe, S., Okomo, U., Muhammad, A.-K. et al. (15 more authors) (2019) Community-acquired invasive bacterial disease in urban Gambia, 2005–2015: A hospital-based surveillance. Clinical Infectious Diseases, 69 (Supplement_2). S105-S113. ISSN 1058-4838
de Lima, D.S., Cardozo, L.E., Maracaja-Coutinho, V. et al. (8 more authors) (2019) Long noncoding RNAs are involved in multiple immunological pathways in response to vaccination. Proceedings of the National Academy of Sciences, 116 (34). pp. 17121-17126. ISSN 0027-8424
Lindsey, B.B., Jagne, Y.J., Armitage, E.P. et al. (14 more authors) (2019) Effect of a Russian-backbone live-attenuated influenza vaccine with an updated pandemic H1N1 strain on shedding and immunogenicity among children in The Gambia : an open-label, observational, phase 4 study. The Lancet Respiratory Medicine, 7 (8). pp. 665-676. ISSN 2213-2600
Darboe, S., Dobreniecki, S., Jarju, S. et al. (16 more authors) (2019) Prevalence of Panton-Valentine Leukocidin (PVL) and antimicrobial resistance in community-acquired clinical Staphylococcus aureus in an urban Gambian hospital : a 11-year period retrospective pilot study. Frontiers in Cellular and Infection Microbiology, 9. 170.
McTavish, S., Snow, S., Cook, E. et al. (12 more authors) (2019) Genomic and epidemiological evidence of a dominant Panton-Valentine leucocidin-positive Methicillin Resistant Staphylococcus aureus lineage in Sri Lanka and presence among isolates from the United Kingdom and Australia. Frontiers in Cellular and Infection Microbiology, 9. 123. ISSN 2235-2988
Lindsey, B.B., Armitage, E.P., Kampmann, B. et al. (1 more author) (2019) The efficacy, effectiveness, and immunogenicity of influenza vaccines in Africa: a systematic review. Lancet Infectious Diseases, 19 (4). e110-e119. ISSN 1473-3099
Miller, P.D.E., de Silva, T.I. orcid.org/0000-0002-6498-9212, Leonard, H. et al. (6 more authors) (2019) A comparison of viral microneutralization and haemagglutination inhibition assays as measures of seasonal inactivated influenza vaccine immunogenicity in the first year after reduced intensity conditioning, lymphocyte depleted allogeneic haematopoietic stem cell transplant. Vaccine, 37 (3). pp. 452-457. ISSN 0264-410X
Miller, P.D.E., Forster, A.S., de Silva, T.I. orcid.org/0000-0002-6498-9212 et al. (9 more authors) (2018) Sociodemographic and psychological determinants of influenza vaccine intention among recipients of autologous and allogeneic haematopoietic stem cell transplant: a cross-sectional survey of UK transplant recipients using a modified health belief model. BMJ OPEN, 8 (8). e021222. ISSN 2044-6055
Knight, G.M., Clarkson, M. and de Silva, T.I. orcid.org/0000-0002-6498-9212 (2018) Potential impact of influenza vaccine roll-out on antibiotic use in Africa. Journal of Antimicrobial Chemotherapy, 73 (8). pp. 2197-2200. ISSN 0305-7453
Armitage, E.T., Camara, J., Bah, S. et al. (4 more authors) (2018) Acceptability of intranasal live attenuated influenza vaccine; influenza knowledge and vaccine intent in The Gambia. Vaccine, 36 (13). pp. 1772-1780. ISSN 0264-410X
James, K.L., de Silva, T.I. orcid.org/0000-0002-6498-9212, Brown, K. et al. (5 more authors) (2018) Low-bias RNA sequencing of the HIV-2 genome from blood plasma. Journal of Virology, 93. e00677-18. ISSN 0022-538X
de Silva, T.I. orcid.org/0000-0002-6498-9212, Gould, V., Mohammed, N.I. et al. (8 more authors) (2017) Comparison of mucosal lining fluid sampling methods and influenza-specific IgA detection assays for use in human studies of influenza immunity. Journal of Immunological Methods, 449. pp. 1-6. ISSN 0022-1759
Miller, P.D., de Silva, T.I., Skinner, R. et al. (8 more authors) (2017) Routine vaccination practice after adult and paediatric allogeneic haematopoietic stem cell transplant: a survey of UK NHS programmes. Bone Marrow Transplant, 52. pp. 775-777. ISSN 0268-3369
de Silva, T.I. orcid.org/0000-0002-6498-9212 and Kampmann, B. (2017) Value of immunogenicity studies of influenza vaccine in resource-limited settings. Lancet Global Health, 5 (3). e274.
Garcia-Knight, M.A., Slyker, J., Payne, B.L. et al. (8 more authors) (2016) Viral Evolution and Cytotoxic T Cell Restricted Selection in Acute Infant HIV-1 Infection. Scientific Reports, 6. 29536. ISSN 2045-2322
Fryer, H.R., Van Tienen, C., Van Der Loeff, M.S. et al. (5 more authors) (2015) Predicting the extinction of HIV-2 in rural Guinea-Bissau. AIDS, 29 (18). pp. 2479-2486. ISSN 0269-9370
van Tienen, C., de Silva, T.I. orcid.org/0000-0002-6498-9212, Junior Alcantara, L.C. et al. (8 more authors) (2012) Molecular epidemiology of endemic Human T-Lymphotropic virus type 1 in a rural community in Guinea-Bissau. PLoS Neglected Tropical Diseases, 6 (6). e1690. ISSN 1935-2727
Peterson, K., Jallow, S., Rowland-Jones, S.L. et al. (1 more author) (2011) Antiretroviral Therapy for HIV-2 Infection: Recommendations for Management in Low-Resource Settings. AIDS Research and Treatment, 2011. 463704. ISSN 2090-1240
de Silva, T.I. orcid.org/0000-0002-6498-9212, Turner, R., Hue, S. et al. (8 more authors) (2010) HIV-1 subtype distribution in the Gambia and the significant presence of CRF49_cpx, a novel circulating recombinant form. Retrovirology, 7. 82. ISSN 1742-4690
Preprint
Leary, S. orcid.org/0000-0002-6966-2294, Gaudieri, S. orcid.org/0000-0001-6873-0198, Parker, M.D. orcid.org/0000-0003-2999-3870 et al. (17 more authors) (2021) Generation of a novel SARS-CoV-2 sub-genomic RNA due to the R203K/G204R variant in nucleocapsid: homologous recombination has potential to change SARS-CoV-2 at both protein and RNA level. [Preprint] (Submitted)
Lindsey, B.B. orcid.org/0000-0003-4227-2592, Villabona-Arenas, C.J. orcid.org/0000-0001-9928-3968, Campbell, F. et al. (22 more authors) (2021) Characterising within-hospital SARS-CoV-2 transmission events: a retrospective analysis integrating epidemiological and viral genomic data from a UK tertiary care setting across two pandemic waves. [Preprint] (Submitted)
Peacock, T.P. orcid.org/0000-0001-7077-2928, Sheppard, C.M. orcid.org/0000-0002-3285-3804, Brown, J.C. orcid.org/0000-0001-6849-3962 et al. (5 more authors) (2021) The SARS-CoV-2 variants associated with infections in India, B.1.617, show enhanced spike cleavage by furin. [Preprint] (Submitted)
de Silva, T.I. orcid.org/0000-0002-6498-9212, Liu, G., B Lindsey, B. et al. (16 more authors) (2021) The impact of viral mutations on recognition by SARS-CoV-2 specific T-cells. [Preprint] (Submitted)