Items where authors include "Zeggini, E."

Article

Bittner, N. orcid.org/0000-0002-8588-185X, Shi, C., Zhao, D. et al. (12 more authors) (2024) Primary osteoarthritis chondrocyte map of chromatin conformation reveals novel candidate effector genes. Annals of the Rheumatic Diseases, 83 (8). pp. 1048-1059. ISSN 0003-4967

Kreitmaier, P., Park, Y.-C., Swift, D. et al. (3 more authors) (2024) Epigenomic profiling of the infrapatellar fat pad in osteoarthritis. Human Molecular Genetics, 33 (6). pp. 501-509. ISSN 0964-6906

Faber, B.G. orcid.org/0000-0003-4102-0190, Frysz, M. orcid.org/0000-0001-5729-778X, Hartley, A.E. orcid.org/0000-0003-4932-1588 et al. (17 more authors) (2023) A genome-wide association study meta-analysis of alpha angle suggests cam-type morphology may be a specific feature of hip osteoarthritis in older adults. Arthritis & Rheumatology, 75 (6). pp. 900-909. ISSN 2326-5191

Hartley, A. orcid.org/0000-0003-4932-1588, Sanderson, E. orcid.org/0000-0001-5188-5775, Granell, R. et al. (60 more authors) (2022) Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index. International Journal of Epidemiology, 51 (4). pp. 1254-1267. ISSN 0300-5771

Kreitmaier, P., Suderman, M., Southam, L. et al. (7 more authors) (2022) An epigenome-wide view of osteoarthritis in primary tissues. The American Journal of Human Genetics, 109 (7). pp. 1255-1271. ISSN 0002-9297

Katsoula, G., Steinberg, J., Tuerlings, M. et al. (6 more authors) (2022) A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis. Human Molecular Genetics, 31 (12). pp. 2090-2105. ISSN 0964-6906

Wilkinson, J.M. orcid.org/0000-0001-5577-3674 and Zeggini, E. (2021) The genetic epidemiology of joint shape and the development of osteoarthritis. Calcified Tissue International, 109 (3). pp. 257-276. ISSN 0171-967X

Steinberg, J., Southam, L., Fontalis, A. orcid.org/0000-0001-5547-288X et al. (8 more authors) (2021) Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis. Annals of the Rheumatic Diseases, 80 (8). pp. 1070-1074. ISSN 0003-4967

Boer, C.G., Yau, M.S., Rice, S.J. et al. (14 more authors) (2021) Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene. Annals of the Rheumatic Diseases, 80 (3). pp. 367-375. ISSN 0003-4967

Steinberg, J., Southam, L., Roumeliotis, T.I. et al. (12 more authors) (2021) A molecular quantitative trait locus map for osteoarthritis. Nature Communications, 12. 1309. ISSN 2041-1723

Butterfield, N.C., Curry, K.F., Steinberg, J. et al. (24 more authors) (2021) Accelerating functional gene discovery in osteoarthritis. Nature Communications, 12 (1). 467. ISSN 2041-1723

MacInnes, S.J., Hatzikotoulas, K., Fenstad, A.M. et al. (9 more authors) (2019) The 2018 Otto Aufranc Award: How does genome-wide variation affect osteolysis risk after THA? Clinical Orthopaedics and Related Research, 477 (2). pp. 297-309. ISSN 0009-921X

Tachmazidou, I., Hatzikotoulas, K. orcid.org/0000-0002-4699-3672, Southam, L. orcid.org/0000-0002-7546-9650 et al. (19 more authors) (2019) Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. Nature Genetics, 51. pp. 230-236. ISSN 1061-4036

Hackinger, S., Prins, B., Mamakou, V. et al. (12 more authors) (2018) Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia. Translational Psychiatry, 8. 252. ISSN 2158-3188

Steinberg, J., Brooks, R.A., Southam, L. et al. (8 more authors) (2018) Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis. Rheumatology, 57 (8). pp. 1481-1489. ISSN 1462-0324

Hatzikotoulas, K. orcid.org/0000-0002-4699-3672, Roposch, A., Case Control Consortium, D.D.H. et al. (14 more authors) (2018) Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5. Communications Biology, 1. 56. ISSN 2399-3642

Casalone, E., Tachmazidou, I., Zengini, E. et al. (9 more authors) (2018) A novel variant in GLIS3 is associated with osteoarthritis. Annals of the Rheumatic Diseases, 77 (4). pp. 620-622. ISSN 0003-4967

Zengini, E., Hatzikotoulas, K., Tachmazidou, I. et al. (20 more authors) (2018) Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. Nature Genetics, 50 (4). pp. 549-558. ISSN 1061-4036

Marouli, E., Kanoni, S., Mamakou, V. et al. (16 more authors) (2017) Evaluating the glucose raising effect of established loci via a genetic risk score. PLoS One, 12 (11). e0186669. ISSN 1932-6203

Hackinger, S., Trajanoska, K., Styrkarsdottir, U. et al. (19 more authors) (2017) Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus. Human Molecular Genetics, 26 (19). pp. 3850-3858. ISSN 0964-6906

Cibrián Uhalte, E., Wilkinson, J.M. orcid.org/0000-0001-5577-3674, Southam, L. et al. (1 more author) (2017) Pathways to understanding the genomic aetiology of osteoarthritis. Human Molecular Genetics, 26 (R2). R193-R201. ISSN 0964-6906

Steinberg, J., Ritchie, G.R.S., Roumeliotis, T.I. et al. (15 more authors) (2017) Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis. Scientific Reports, 7 (1). 8935. ISSN 2045-2322

Panoutsopoulou, K., Thiagarajah, S., Zengini, E. et al. (12 more authors) (2017) Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis. Annals of the Rheumatic Diseases, 76 (7). pp. 1199-1206. ISSN 0003-4967

Steinberg, J., Shah, K.M., Gartland, A. orcid.org/0000-0002-3712-2437 et al. (2 more authors) (2017) The effects of chronic cobalt and chromium exposure after metal-on-metal hip resurfacing: An epigenome-wide association pilot study. Journal of Orthopaedic Research. ISSN 0736-0266

Gurdasani, D., Carstensen, T., Tekola-Ayele, F. et al. (39 more authors) (2015) The African Genome Variation Project shapes medical genetics in Africa. Nature, 517 (7534). pp. 327-332. ISSN 0028-0836

Evangelou, E., Kerkhof, H.J., Styrkarsdottir, U. et al. (64 more authors) (2014) A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip. Annals of the Rheumatic Diseases (ARD), 73 (12). pp. 2130-2136. ISSN 0003-4967

Rodriguez-Fontenla, C., Calaza, M., Evangelou, E. et al. (45 more authors) (2014) Assessment of Osteoarthritis Candidate Genes in a Meta-Analysis of Nine Genome-Wide Association Studies. Arthritis & Rheumatology, 66 (4). pp. 940-949. ISSN 2326-5191

Elliott, K.S., Chapman, K., Day-Williams, A. et al. (23 more authors) (2013) Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data. Annals of the Rheumatic Diseases (ARD), 72 (6). pp. 935-941. ISSN 0003-4967

Hudson, G., Panoutsopoulou, K., Wilson, I. et al. (22 more authors) (2013) No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls. Annals of the Rheumatic Diseases (ARD), 72 (1). pp. 136-139. ISSN 0003-4967

Southam, L., Panoutsopoulou, K., Rayner, N.W. et al. (18 more authors) (2011) The effect of genome-wide association scan quality control on imputation outcome for common variants. European Journal of Human Genetics, 19 (5). pp. 610-614.

Panoutsopoulou, K., Southam, L., Elliott, K.S. et al. (73 more authors) (2010) Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study. Annals of the Rheumatic Diseases (ARD), 70 (5). pp. 864-867. ISSN 0003-4967

Proceedings Paper

Kreitmaier, P., Suderman, M., Southam, L. et al. (3 more authors) (2020) Epigenome-wide association study in knee osteoarthritis generates novel insights into disease mechanisms. In: Osteoarthritis and Cartilage. 2020 OARSI World Congress on Osteoarthritis : Promoting Clinical and Basic Research in Osteoarthritis, 30 Apr - 03 May 2020, Vienna, Austria. Elsevier BV , S53.

Katsoula, G., Southam, L., Steinberg, J. et al. (3 more authors) (2020) A comprehensive transcriptional map of knee osteoarthritis. In: Osteoarthritis and Cartilage. 2020 OARSI World Congress on Osteoarthritis, 30 Apr - 03 May 2020, Vienna, Austria. Elsevier , S346-S346.

Hatzikotoulas, K., Roposch, A., Shah, K.M. et al. (13 more authors) (2017) National clinical audit data decodes the genetic architecture of developmental dysplasia of the hip. In: Osteoarthritis and Cartilage. 2017 OARSI World Congress on Osteoarthritis: Promoting Clinical and Basic Research in Osteoarthritis, 27-30 Apr 2017, Las Vegas, USA. Elsevier , S36-S37.

Preprint

Steinberg, J., Southam, L., Butterfield, N.C. et al. (15 more authors) (2019) Decoding the genomic basis of osteoarthritis. [Preprint]