Items where authors include "Wu, Liang"

Article

Chen, Yurong, van den Nieuwendijk, Adrianus M. C. H., Wu, Liang orcid.org/0000-0003-0294-7065 et al. (6 more authors) (2024) Molecular basis for inhibition of heparanases and β-glucuronidases by siastatin B. Journal of the American Chemical Society. 125–133. ISSN 1520-5126

Kok, Ken, Kuo, Chi Lin, Katzy, Rebecca E. et al. (10 more authors) (2022) 1,6- epi-Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal α-Glucosidase Stabilizer for the Treatment of Pompe Disease. Journal of the American Chemical Society. 14819–14827. ISSN 1520-5126

Boer, Casper de, Armstrong, Zachary, Lit, Vincent A. J. et al. (15 more authors) (2022) Mechanism based heparanase inhibitors reduce cancer metastasis in vivo. Proceedings of the National Academy of Sciences of the United States of America. e2203167119. ISSN 1091-6490

Chhabra, Mohit, Wilson, Jennifer C., Wu, Liang orcid.org/0000-0003-0294-7065 et al. (3 more authors) (2022) Structural insights into pixatimod (PG545) inhibition of heparanase, a key enzyme in cancer and viral infections. Chemistry : A European Journal. e202104222. ISSN 1521-3765

Rowland, Rhianna J., Chen, Yurong, Breen, Imogen et al. (9 more authors) (2021) Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents. Chemistry : A European Journal. ISSN 1521-3765

Darby, John F. orcid.org/0000-0003-2754-6348, Gilio, Amelia K., Piniello, Beatriz et al. (6 more authors) (2020) Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase v. ACS Catalysis. pp. 8590-8596. ISSN 2155-5435

Deen, Matthew C., Proceviat, Cameron, Shan, Xiaoyang et al. (4 more authors) (2020) Selective Fluorogenic β-Glucocerebrosidase Substrates for Convenient Analysis of Enzyme Activity in Cell and Tissue Homogenates. ACS Chemical Biology. ISSN 1554-8937

Wu, Liang orcid.org/0000-0003-0294-7065, Armstrong, Zach, Schröder, Sybrin P. et al. (5 more authors) (2019) An overview of activity-based probes for glycosidases. Current Opinion in Chemical Biology. pp. 25-36. ISSN 1367-5931

Bule, Pedro, Chuzel, Léa, Blagova, Elena et al. (7 more authors) (2019) Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action. Nature Communications. ISSN 2041-1723

Artola, Marta, Hedberg, Christinne, Rowland, Rhianna J. et al. (11 more authors) (2019) α-D-Gal-cyclophellitol cyclosulfamidate is a Michaelis complex analog that stabilizes therapeutic lysosomal α-galactosidase A in Fabry disease. Chemical Science. ISSN 2041-6539

Schröder, Sybrin P., De Boer, Casper, McGregor, Nicholas G.S. et al. (22 more authors) (2019) Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Aspergillus Secretomes Using Activity-Based Probes. ACS Central Science. pp. 1067-1078. ISSN 2374-7943

Coyle, Travis, Wu, Liang orcid.org/0000-0003-0294-7065, Debowski, Aleksandra et al. (2 more authors) (2019) Synthetic and crystallographic insight into exploiting sp2‐hybridization in the development of α‐L‐fucosidase inhibitors. Chembiochem. ISSN 1439-7633

Wu, Liang orcid.org/0000-0003-0294-7065 and Davies, Gideon J. orcid.org/0000-0002-7343-776X (2018) Structure of the GH9 glucosidase/glucosaminidase from Vibrio cholerae. Acta Crystallographica Section F: Structural Biology Communications. pp. 512-523. ISSN 2053-230X

Schröder, Sybrin P, Wu, Liang orcid.org/0000-0003-0294-7065, Artola, Marta et al. (9 more authors) (2018) Gluco-1 H-imidazole:A New Class of Azole-Type β-Glucosidase Inhibitor. Journal of the American Chemical Society. pp. 1-4. ISSN 1520-5126

Lahav, Daniël, Liu, Bing, van den Berg, Richard J. B. H. N. et al. (15 more authors) (2017) A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase. Journal of the American Chemical Society. pp. 14192-14197. ISSN 1520-5126

Wu, Liang orcid.org/0000-0003-0294-7065, Jiang, Jianbing, Jin, Yi orcid.org/0000-0002-6927-4371 et al. (12 more authors) (2017) Activity-based probes for functional interrogation of retaining β-glucuronidases. NATURE CHEMICAL BIOLOGY. pp. 867-873. ISSN 1552-4450

Artola, Marta, Wu, Liang orcid.org/0000-0003-0294-7065, Ferraz, Maria J. et al. (10 more authors) (2017) 1,6-Cyclophellitol Cyclosulfates:A New Class of Irreversible Glycosidase Inhibitor. ACS Central Science. pp. 784-793. ISSN 2374-7943

Charoenwattanasatien, Ratana, Pengthaisong, Salila, Breen, Imogen et al. (11 more authors) (2016) Bacterial β-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2). ACS Chemical Biology. pp. 1891-1900. ISSN 1554-8937

Jiang, Jianbing, Kuo, Chi-Lin, Wu, Liang orcid.org/0000-0003-0294-7065 et al. (10 more authors) (2016) Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes. ACS Central Science. pp. 351-358. ISSN 2374-7943