Items where authors include "Whitworth, A.J."

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Number of items: 11.

Article

Castelli, L.M., Lin, Y.-H., Sanchez-Martinez, A. et al. (19 more authors) (2023) A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. Science Translational Medicine, 15 (685). ISSN 1946-6234

Castelli, L.M., Cutillo, L., Souza, C.D.S. et al. (14 more authors) (2021) SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export : genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis. Molecular Neurodegeneration, 16 (1). 53.

Hautbergue, G.M. orcid.org/0000-0002-1621-261X, Castelli, L.M., Ferraiuolo, L. et al. (23 more authors) (2017) SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits. Nature Communications, 8. 16063 (2017).

Webster, C.P., Smith, E.F., Bauer, C.S. et al. (12 more authors) (2016) The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy. EMBO Journal, 35 (15). pp. 1656-1676.

Baldwin, K.R., Godena, V.K., Hewitt, V.L. et al. (1 more author) (2016) Axonal transport defects are a common phenotype in Drosophila models of ALS. Human Molecular Genetics, 25 (12). pp. 2378-2392. ISSN 0964-6906

Malik, B.R., Godena, V.K. and Whitworth, A.J. (2015) VPS35 pathogenic mutations confer no dominant toxicity but partial loss of function in Drosophila and genetically interact with parkin. Human Molecular Genetics. ISSN 0964-6906

Pogson, J.H., Ivatt, R.M., Sanchez-Martinez, A. et al. (4 more authors) (2014) The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy. PLoS Genetics, 10 (11). e1004815. ISSN 1553-7390

Godena, V.K., Brookes-Hocking, N., Moller, A. et al. (6 more authors) (2014) Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations. Nature Communications, 5. 5245 . ISSN 2041-1723

Ziviani, E., Tao, R.N. and Whitworth, A.J. (2010) Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin. Proceedings of the National Academy of Sciences of the United States of America , 107 (11). pp. 5018-5023. ISSN 0027-8424

Whitworth, A.J. and Pallanck, L.J. (2009) The PINK1/Parkin pathway: a mitochondrial quality control system? Journal of Bioenergetics and Biomembranes, 41 (6). pp. 499-503. ISSN 0145-479X

Tain, L.S., Mortiboys, H., Tao, R.N. et al. (3 more authors) (2009) Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss. Nature Neuroscience , 12 (9). pp. 1129-1135. ISSN 1097-6256

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