Items where authors include "West, R.J.H."

Article

Keerie, A.F., Martins, R.R., Allen, C.F. et al. (24 more authors) (2025) M102 activates both NRF2 and HSF1 transcription factor pathways and is neuroprotective in cell and animal models of amyotrophic lateral sclerosis. Molecular Neurodegeneration, 20. 118.

O’Brien, D., Alhathli, E. orcid.org/0009-0008-2147-9715, Harwood, C. et al. (12 more authors) (2025) Extreme exercise in males is linked to mTOR signalling and onset of amyotrophic lateral sclerosis. Brain, 148 (10). pp. 3652-3664. ISSN 0006-8950

Webster, C.P. orcid.org/0000-0003-4197-2036, Hall, B. orcid.org/0009-0008-4274-9796, Crossley, O.M. et al. (14 more authors) (2025) RuvBL1/2 reduce toxic dipeptide repeat protein burden in multiple models of C9orf72-ALS/FTD. Life Science Alliance, 8 (2). e202402757. ISSN 2575-1077

Bennett, C.L., Dastidar, S., Arnold, F.J. et al. (10 more authors) (2023) Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity. Acta Neuropathologica Communications, 11 (1). 164. ISSN 2051-5960

Sharpe, J.L., Harper, N.S., Garner, D.R. et al. (1 more author) (2021) Modeling C9orf72-related frontotemporal dementia and amyotrophic lateral sclerosis in drosophila. Frontiers in Cellular Neuroscience, 15. 770937. ISSN 1662-5102

Ugbode, C. and West, R.J.H. orcid.org/0000-0001-9873-2258 (2021) Lessons learned from CHMP2B, implications for frontotemporal dementia and amyotrophic lateral sclerosis. Neurobiology of Disease, 147. 105144. ISSN 0969-9961

West, R.J.H. orcid.org/0000-0001-9873-2258, Sharpe, J.L., Voelzmann, A. et al. (4 more authors) (2020) Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila. Acta Neuropathologica Communications, 8. 158.

West, R.J.H. orcid.org/0000-0001-9873-2258, Ugbode, C., Fort-Aznar, L. et al. (1 more author) (2020) Neuroprotective activity of ursodeoxycholic acid in CHMP2B Intron5 models of frontotemporal dementia. Neurobiology of Disease, 144. 105047. ISSN 0969-9961

Lu, Y., West, R.J.H. orcid.org/0000-0001-9873-2258, Pons, M. et al. (2 more authors) (2020) Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila. Scientific Reports, 10 (1). 14221.

Vilidaite, G., Norcia, A.M., West, R.J.H. orcid.org/0000-0001-9873-2258 et al. (4 more authors) (2018) Autism sensory dysfunction in an evolutionarily conserved system. Proceedings of the Royal Society B: Biological Sciences, 285 (1893). 20182255. ISSN 0962-8452

West, R.J.H. orcid.org/0000-0001-9873-2258, Briggs, L., Perona Fjeldstad, M. et al. (2 more authors) (2018) Sphingolipids regulate neuromuscular synapse structure and function in Drosophila. Journal of Comparative Neurology, 526 (13). pp. 1995-2009. ISSN 0021-9967

West, R.J.H. orcid.org/0000-0001-9873-2258, Ugbode, C., Gao, F.-B. et al. (1 more author) (2018) The pro-apoptotic JNK scaffold POSH/SH3RF1 mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia. Human Molecular Genetics, 27 (8). pp. 1382-1395. ISSN 0964-6906

Himmelberg, M.M., West, R.J.H. orcid.org/0000-0001-9873-2258, Wade, A.R. et al. (1 more author) (2018) A perceptive plus in Parkinson's disease. Movement Disorders, 33 (2). p. 248. ISSN 0885-3185