Items where authors include "Tucker, Julie Ann"

Article

Miller, Duncan C., Reuillon, Tristan, Molyneux, Lauren et al. (23 more authors) (2022) Parallel Optimisation of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Chemical Tool. JOURNAL OF MEDICINAL CHEMISTRY. pp. 6513-6540. ISSN 0022-2623

Al-Khawaldeh, Islam, Alyassiri, Mohammed, Aldred, Greg et al. (29 more authors) (2021) An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK). JOURNAL OF MEDICINAL CHEMISTRY. 10001–10018. ISSN 0022-2623

Tucker, Julie Ann orcid.org/0000-0002-6119-676X and Martin, Mathew P. (2021) Recent Advances in Kinase Drug Discovery Part I: the Editors’ Take. International Journal of Molecular Sciences. pp. 1-6. ISSN 1422-0067

Cook, Simon, Tucker, Julie Ann orcid.org/0000-0002-6119-676X and Lochhead, Pamela (2020) Small molecule ERK5 kinase inhibitors paradoxically activate ERK5 signalling: be careful what you wish for... Biochemical Society transactions. ISSN 1470-8752

Lochhead, Pamela, Tucker, Julie Ann orcid.org/0000-0002-6119-676X, Tatum, Natalie et al. (8 more authors) (2020) Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors. Nature Communications. 1383. ISSN 2041-1723

Wilmes, Stephan, Hafer, Maximillian, Vuorio, Joni et al. (15 more authors) (2020) Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations. Science. pp. 643-652. ISSN 0036-8075

Tucker, Julie Ann orcid.org/0000-0002-6119-676X, Myers, Stephanie M., Miller, Duncan C. et al. (27 more authors) (2019) Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4. European Journal of Medicinal Chemistry. pp. 530-543. ISSN 0223-5234

Waszkowycz, Bohdan, Smith, Kate M., McGonagle, Alison E. et al. (17 more authors) (2018) Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG):Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. JOURNAL OF MEDICINAL CHEMISTRY. pp. 10767-10792. ISSN 0022-2623