Items where authors include "Sabroe, I."
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Dowey, R., Cole, J., Roger Thompson, A.A. et al. (11 more authors) (2022) Enhanced neutrophil extracellular trap formation in COVID-19 is inhibited by the protein kinase C inhibitor ruboxistaurin. ERJ Open Research, 8 (2). 00596-2021. ISSN 2312-0541
Wardle, M., Nair, A., Saunders, S. et al. (13 more authors) (2022) Elective lower limb orthopaedic arthroplasty surgery in patients with pulmonary hypertension. Pulmonary Circulation, 12 (1). e12019. ISSN 2045-8940
Mussell, G.T., Marshall, H. orcid.org/0000-0002-7425-1449, Smith, L.J. et al. (12 more authors) (2021) Xenon ventilation MRI in difficult asthma; initial experience in a clinical setting. European Respiratory Journal, 7 (3). 00785-2020. ISSN 0903-1936
Stewart, N.J., Smith, L.J., Chan, H.-F. et al. (16 more authors) (2021) Lung MRI with hyperpolarised gases : current & future clinical perspectives. The British Journal of Radiology, 94. 20210207. ISSN 0007-1285
Dowey, R., Iqbal, A. orcid.org/0000-0002-5648-0539, Heller, S.R. orcid.org/0000-0002-2425-9565 et al. (2 more authors) (2021) A bittersweet response to infection in diabetes ; targeting neutrophils to modify inflammation and improve host immunity. Frontiers in Immunology, 12. 678771.
Bauchmuller, K., Condliffe, R., Southern, J. et al. (9 more authors) (2021) Critical care outcomes in patients with pre-existing pulmonary hypertension: insights from the ASPIRE registry. ERJ Open Research, 7 (2). 00046-2021. ISSN 2312-0541
Sabroe, I., Mather, S., Wilson, A. et al. (4 more authors) (2021) Error, injustice, and physician wellbeing. The Lancet, 397 (10277). pp. 872-873. ISSN 0140-6736
Lewis, R.A., Armstrong, I., Bergbaum, C. et al. (33 more authors) (2021) EmPHasis-10 health-related quality of life score predicts outcomes in patients with idiopathic and connective tissue disease-associated pulmonary arterial hypertension: results from a UK multi-centre study. European Respiratory Journal, 57 (2). 2000124. ISSN 0903-1936
Burnap, S.A., Mayr, U., Shankar-Hari, M. et al. (6 more authors) (2021) A proteomics-based assessment of inflammation signatures in endotoxemia. Molecular & Cellular Proteomics, 20. 100021. ISSN 1535-9476
Lewis, R.A., Billings, C.G., Hurdman, J.A. et al. (17 more authors) (2021) Maximal exercise testing using the incremental shuttle walking test can be used to risk stratify patients with pulmonary arterial hypertension. Annals of the American Thoracic Society, 18 (1). pp. 34-43. ISSN 2329-6933
Rawlings, G.H. orcid.org/0000-0003-4962-3551, Beail, N. orcid.org/0000-0002-7916-9313, Armstrong, I. et al. (4 more authors) (2020) Adults’ experiences of living with pulmonary hypertension: a thematic synthesis of qualitative studies. BMJ Open, 10 (12). e041428. ISSN 2044-6055
Elliott, G.K., Millard, C. orcid.org/0000-0001-5517-492X and Sabroe, I. (2020) The utilization of cultural movements to overcome stigma in narrative of postnatal depression. Frontiers in Psychiatry, 11. 532600. ISSN 1664-0640
Lewis, R.A., Billings, C.G., Bolger, A. et al. (19 more authors) (2020) Partial anomalous pulmonary venous drainage in patients presenting with suspected pulmonary hypertension: A series of 90 patients from the ASPIRE registry. Respirology, 25 (10). pp. 1066-1072. ISSN 1323-7799
Swift, A.J. orcid.org/0000-0002-8772-409X, Dwivedi, K., Johns, C. et al. (14 more authors) (2020) Diagnostic accuracy of CT pulmonary angiography in suspected pulmonary hypertension. European Radiology, 30 (9). pp. 4918-4929. ISSN 0938-7994
Marsh, E.K., Prestwich, E.C., Williams, L. et al. (17 more authors) (2020) Pellino-1 regulates the responses of the airway to viral infection. Frontiers in Cellular and Infection Microbiology, 10. 456.
Lewis, R.A., Thompson, A.A.R. orcid.org/0000-0002-0717-4551, Billings, C.G. et al. (10 more authors) (2020) Mild parenchymal lung disease and/or low diffusion capacity impacts survival and treatment response in patients diagnosed with idiopathic pulmonary arterial hypertension. European Respiratory Journal, 55 (6). 2000041. ISSN 0903-1936
Braza-Boïls, A., Barwari, T., Gutmann, C. et al. (9 more authors) (2020) Circulating microRNA levels indicate platelet and leukocyte Aativation in endotoxemia despite platelet P2Y12 inhibition. International Journal of Molecular Sciences, 21 (8). 2897. ISSN 1661-6596
Lewis, R.A., Johns, C.S. orcid.org/0000-0003-3724-0430, Cogliano, M. et al. (20 more authors) (2020) Identification of cardiac MRI thresholds for risk stratification in pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine, 201 (4). pp. 458-468. ISSN 1073-449X
Rahman, A., Henry, K.M., Herman, K.D. et al. (17 more authors) (2019) Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation. eLife, 8. 50990.
Mills, J.T., Schwenzer, A., Marsh, E.K. et al. (4 more authors) (2019) Airway epithelial cells generate pro-inflammatory Tenascin-C and small extracellular vesicles in response to TLR3 stimuli and rhinovirus infection. Frontiers in Immunology, 10.
Wilson, A., Millard, C. and Sabroe, I. orcid.org/0000-0001-9750-8975 (2019) Physician narratives of illness. The Lancet, 394 (10192). pp. 20-21. ISSN 0140-6736
Iqbal, A. orcid.org/0000-0002-5648-0539, Prince, L.R., Novodvorsky, P. orcid.org/0000-0002-3292-7586 et al. (13 more authors) (2019) Effect of hypoglycemia on inflammatory responses and the response to low dose endotoxemia in humans. Journal of Clinical Endocrinology and Metabolism, 104 (4). pp. 1187-1199. ISSN 0021-972X
Germain, L. and Sabroe, I. orcid.org/0000-0001-9750-8975 (2019) The care of dying people in 16th- and 17th-century England. Death Studies, 44 (5). pp. 270-277. ISSN 0748-1187
Manley, G.C.A. orcid.org/0000-0003-1120-3578, Stokes, C.A., Marsh, E.K. et al. (2 more authors) (2019) DUSP10 Negatively Regulates the Inflammatory Response to Rhinovirus Through IL-1β Signalling. Journal of Virology. ISSN 0022-538X
Johns, C.S. orcid.org/0000-0003-3724-0430, Kiely, D.G., Rajaram, S. et al. (13 more authors) (2018) Diagnosis of pulmonary hypertension with cardiac MRI: derivation and validation of regression models. Radiology. ISSN 0033-8419
Quadery, S.R., Swift, A.J., Billings, C. et al. (23 more authors) (2018) The impact of patient choice on survival in chronic thromboembolic pulmonary hypertension. European Respiratory Journal , 52 (3). 1800589. ISSN 0903-1936
Farkas, D., Thompson, A.A.R. orcid.org/0000-0002-0717-4551, Bhagwani, A.R. et al. (14 more authors) (2018) Toll-like receptor 3 is a therapeutic target for pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. ISSN 1073-449X
Peinhaupt, M., Roula, D., Theiler, A. et al. (7 more authors) (2018) DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator. Journal of Leukocyte Biology, 104 (1). pp. 159-171. ISSN 0741-5400
Billings, C.G., Lewis, R., Armstrong, I.J. et al. (10 more authors) (2018) Incremental Shuttle Walking Test Distance Is Reduced in Patients With Pulmonary Hypertension in World Health Organisation Functional Class I. Frontiers in Medicine, 5. 172. ISSN 2296-858X
Charalampopoulos, A., Lewis, R., Hickey, P. orcid.org/0000-0002-4683-7696 et al. (5 more authors) (2018) Pathophysiology and diagnosis of pulmonary hypertension due to left heart disease. Frontiers in Medicine, 5. 174.
Hamilton, N. orcid.org/0000-0002-3299-9133, Sabroe, I. orcid.org/0000-0001-9750-8975 and Renshaw, S.A. orcid.org/0000-0003-1790-1641 (2018) A method for transplantation of human HSCs into zebrafish, to replace humanised murine transplantation models. F1000Research, 7 (594). ISSN 2046-1402
Prince, L.R., Dannewitz Prosseda, S., Higgins, K. et al. (10 more authors) (2017) NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival. Blood, 130 (8). pp. 1014-1025. ISSN 0006-4971
Goddard, J., Armstrong, I., Kiely, D. et al. (5 more authors) (2017) Combining creative writing and narrative analysis to deliver new insights into the impact of pulmonary hypertension. BMJ Open Respiratory Research, 4 (1). e000184.
Billings, C.G., Hurdman, J.A., Condliffe, R.A. et al. (13 more authors) (2017) Incremental Shuttle Walking Test Distance and Autonomic Dysfunction Predict Survival in Pulmonary Arterial Hypertension. The Journal of Heart and Lung Transplantation. ISSN 1053-2498
van Baalen, S., Carusi, A., Sabroe, I. orcid.org/0000-0001-9750-8975 et al. (1 more author) (2016) A social-technological epistemology of clinical decision-making as mediated by imaging. Journal of Evaluation in Clinical Practice. ISSN 1356-1294
Stokes, C., Edwards, M., Mohdhe, M. et al. (9 more authors) (2016) Human rhinovirus induced inflammatory responses are inhibited by phosphatidylserine containing liposomes. Mucosal Immunology, 9 (5). pp. 1303-1316. ISSN 1935-3456
Stokes, C.A., Kaur, R., Edwards, M.R. et al. (10 more authors) (2016) Human rhinovirus-induced inflammatory responses are inhibited by phosphatidylserine containing liposomes. Mucosal Immunology, 9 (5). pp. 1303-1316. ISSN 1933-0219
Heaney, L.G., Djukanovic, R., Woodcock, A. et al. (33 more authors) (2016) Research in progress: Medical Research Council United Kingdom Refractory Asthma Stratification Programme (RASP-UK). THORAX, 71. pp. 187-189. ISSN 0040-6376
Ramjug, S., Hussain, N., Hurdman, J. et al. (6 more authors) (2016) Pulmonary arterial hypertension associated with congenital heart disease: Comparison of clinical and anatomic-pathophysiologic classification. The Journal of Heart and Lung Transplantation, 35 (5). pp. 610-618. ISSN 1053-2498
Thomas, M.R., Outteridge, S.N., Ajjan, R.A. et al. (10 more authors) (2015) Platelet P2Y(12) Inhibitors Reduce Systemic Inflammation and Its Prothrombotic Effects in an Experimental Human Model. Arteriosclerosis, Thrombosis, and Vascular Biology, 35 (12). pp. 2562-2570. ISSN 1079-5642
Alsharif, K.F., Thomas, M.R., Judge, H.M. et al. (5 more authors) (2015) Ticagrelor potentiates adenosine-induced stimulation of neutrophil chemotaxis and phagocytosis. Vascular Pharmacology, 71. pp. 201-207. ISSN 1537-1891
Alsharif, K.F., Thomas, M.R., Judge, H.M. et al. (5 more authors) (2015) Ticagrelor potentiates adenosine-induced stimulation of neutrophil chemotaxis and phagocytosis. Vascular Pharmacology, 71. pp. 201-207. ISSN 1537-1891
Rajaram, S., Swift, A.J., Condliffe, R. et al. (8 more authors) (2015) CT features of pulmonary arterial hypertension and its major subtypes: a systematic CT evaluation of 292 patients from the ASPIRE Registry. Thorax, 70 (4). pp. 382-387. ISSN 0040-6376
Ismail, S., Stokes, C.A., Prestwich, E.C. et al. (4 more authors) (2014) Phosphoinositide-3 kinase inhibition modulates responses to rhinovirus by mechanisms that are predominantly independent of autophagy. PLoS One, 9 (12). e116055. ISSN 1932-6203
Prince, L.R., Maxwell, N.C., Gill, S.K. et al. (5 more authors) (2014) Macrophage phenotype is associated with disease severity in preterm infants with chronic lung disease. PLoS One, 9 (8). - e103059 .
Condliffe, R., Elliot, C.A., Hughes, R.J. et al. (5 more authors) (2014) Management dilemmas in acute pulmonary embolism. Thorax, 69 (2). pp. 174-180. ISSN 0040-6376
Piper, S.C., Ferguson, J., Kay, L. et al. (5 more authors) (2013) The Role of Interleukin-1 and Interleukin-18 in Pro-Inflammatory and Anti-Viral Responses to Rhinovirus in Primary Bronchial Epithelial Cells. PLoS ONE, 8 (5). e63365. ISSN 1932-6203
Basran, A., Jabeen, M., Bingle, L. orcid.org/0000-0002-4587-9384 et al. (12 more authors) (2013) Roles of neutrophils in the regulation of the extent of human inflammation through delivery of IL-1 and clearance of chemokines. Journal of Leukocyte Biology, 93 (1). pp. 7-19. ISSN 0741-5400
Chaudhuri, N., Jary, H., Lea, S. et al. (8 more authors) (2012) Diesel Exhaust Particle Exposure In Vitro Alters Monocyte Differentiation and Function. PLoS ONE, 7 (12). e51107. ISSN 1932-6203
McGrath, E.E., Lawrie, A., Marriott, H.M. et al. (11 more authors) (2012) Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis. Thorax, 67 (9). 796 - 803. ISSN 0040-6376
Marriott, H. M., Gascoyne, K. A., Gowda, R. et al. (8 more authors) (2012) Interleukin-1 regulates CXCL8 release and influences disease outcome in response to streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages. Infection and Immunity, 80 (3). pp. 1140-1149. ISSN 0019-9567
Prince, L.R., Graham, K.J., Connolly, J. orcid.org/0000-0002-9232-7929 et al. (5 more authors) (2012) Staphylococcus aureus Induces Eosinophil Cell Death Mediated by alpha-hemolysin. PLoS ONE, 7 (2). e31506. ISSN 1932-6203
Stokes, C.A., Ismail, S., Dick, E.P. et al. (5 more authors) (2011) Role of interleukin-1 and MyD88-dependent signaling in rhinovirus infection. Journal of Virology, 85 (15). pp. 7912-7921. ISSN 0022-538X
Prince, L.R., Whyte, M.K., Sabroe, I. et al. (1 more author) (2011) The role of TLRs in neutrophil activation. Current Opinion in Pharmacology, 11 (4). pp. 397-403. ISSN 1471-4892
Wardle, D.J., Burgon, J., Sabroe, I. et al. (3 more authors) (2011) Effective caspase inhibition blocks neutrophil apoptosis and reveals Mcl-1 as both a regulator and a target of neutrophil caspase activation. Plos One, 6 (1). Art no.e15768. ISSN 1932-6203
Walmsley, S. R., Chilvers, E. R., Thompson, A. A. et al. (16 more authors) (2011) Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice. The Journal of clinical investigation, 121 (3). pp. 1053-63. ISSN 1558-8238
McGrath, E. E., Marriott, H. M., Lawrie, A. et al. (5 more authors) (2011) TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation. Journal of Leukocyte Biology, 90 (5). pp. 855-65. ISSN 1938-3673
Collini, P., Noursadeghi, M., Sabroe, I. et al. (2 more authors) (2010) Monocyte and macrophage dysfunction as a cause of HIV-1 induced dysfunction of innate immunity. Current molecular medicine, 10 (8). pp. 727-40. ISSN 1875-5666
Bianchi, S. M., Prince, L. R., McPhillips, K. et al. (8 more authors) (2008) Impairment of apoptotic cell engulfment by pyocyanin, a toxic metabolite of Pseudomonas aeruginosa. American journal of respiratory and critical care medicine, 177 (1). pp. 35-43. ISSN 1535-4970
Prince, L. R., Bianchi, S. M., Vaughan, K. M. et al. (8 more authors) (2008) Subversion of a lysosomal pathway regulating neutrophil apoptosis by a major bacterial toxin, pyocyanin. The Journal of Immunology, 180 (5). pp. 3502-11. ISSN 0022-1767
Sabroe, I., Dockrell, D. H., Vogel, S. N. et al. (3 more authors) (2007) Identifying and hurdling obstacles to translational research. Nature reviews. Immunology, 7 (1). pp. 77-82. ISSN 1474-1733
Sabroe, I., Parker, L. C., Dockrell, D. H. et al. (3 more authors) (2007) Targeting the networks that underpin contiguous immunity in asthma and chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine, 175 (4). pp. 306-311. ISSN 1073-449X
Bianchi, S. M., Dockrell, D. H., Renshaw, S. A. et al. (2 more authors) (2006) Granulocyte apoptosis in the pathogenesis and resolution of lung disease. Clinical science, 110 (3). pp. 293-304. ISSN 0143-5221
Sabroe, I., Read, R. C., Whyte, M. K. B. et al. (3 more authors) (2003) Toll-like receptors in health and disease: complex questions remain. The Journal of Immunology, 171 (4). pp. 1630-1635. ISSN 0022-1767
Proceedings Paper
Holland, C., Neal, M., Pippard, B. et al. (9 more authors) (2022) S68 Assessing pulmonary ventilation and treatment response in patients with asthma and COPD using 19F-MRI: results from the LIFT study. In: Thorax. British Thoracic Society Winter Meeting 2022, QEII Centre, Broad Sanctuary, Westminster, London SW1P 3EE, 23 to 25 November 2022, Programme and Abstracts, 23-25 Nov 2022, Westminster, London, United Kingdom. BMJ Publishing Group Ltd and British Thoracic Society , a43-a44.
Lewis, R., Billings, C., Johns, C. et al. (9 more authors) (2018) P16 Identifying partial anomalous pulmonary venous drainage (PAPVD) in patients presenting with suspected pulmonary hypertension (PH). In: Thorax. British Thoracic Society Winter Meeting 2018, 05-07 Dec 2018, London, United kingdom. BMJ Publishing Group Ltd and British Thoracic Society , A104.
Pippard, B., Neal, M., Maunder, A. et al. (6 more authors) (2018) S90 Assessing regional lung ventilation in patients and healthy volunteers using 19F-MRI of inhaled perfluoropropane. In: Thorax. British Thoracic Society Winter Meeting 2018, 05-07 Dec 2018, London, United kingdom. BMJ Publishing Group Ltd and British Thoracic Society , A55-A56.
Quadery, S.R. orcid.org/0000-0002-9261-010X, Swift, A.J. orcid.org/0000-0002-8772-409X, Billings, C. et al. (21 more authors) (2017) P183 Impact of patient choice on survival in patients with chronic thromboembolic pulmonary hypertension offered pulmonary endarterectomy. In: Thorax. British Thoracic Society Winter Meeting 2017, 06-08 Dec 2017, London, United kingdom. BMJ Publishing Group Ltd and British Thoracic Society , A181.
Quadery, S.R. orcid.org/0000-0002-9261-010X, Condliffe, R.A., Billings, C. et al. (11 more authors) (2016) P28 Chronic thromboembolic pulmonary hypertension: long term outcomes in surgical and non-surgical patients. In: Thorax. British Thoracic Society Winter Meeting 2016, 07-09 Dec 2016, London, United kingdom. BMJ Publishing Group , A98.
Ramjug, S., Hussain, N., Hurdman, J. et al. (7 more authors) (2016) S111 Differences in characteristics and outcomes in systemic sclerosis-associated and idiopathic pulmonary arterial hypertension. In: Thorax. British Thoracic Society Winter Meeting 2016, 07-09 Dec 2016, London, United kingdom. BMJ Publishing Group , A66-A67.