Items where authors include "Mortusewicz, O."

Article

Luttens, A. orcid.org/0000-0003-2915-7901, Vo, D.D., Scaletti, E.R. et al. (22 more authors) (2025) Virtual fragment screening for DNA repair inhibitors in vast chemical space. Nature Communications, 16. 1741. ISSN 2041-1723

Valerie, N.C.K. orcid.org/0000-0002-9423-964X, Sanjiv, K., Mortusewicz, O. orcid.org/0000-0002-4290-4994 et al. (21 more authors) (2024) Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM. Nature Communications, 15. 10347. ISSN 2041-1723

Marttila, P. orcid.org/0000-0002-0115-8067, Bonagas, N., Chalkiadaki, C. et al. (12 more authors) (2024) The one‐carbon metabolic enzyme MTHFD2 promotes resection and homologous recombination after ionizing radiation. Molecular Oncology, 18 (9). pp. 2179-2195. ISSN 1574-7891

Walter, M. orcid.org/0000-0003-3241-522X, Mayr, F. orcid.org/0000-0002-0892-7076, Hanna, B.M.F. orcid.org/0000-0001-7027-6553 et al. (4 more authors) (2023) NUDT22 promotes cancer growth through pyrimidine salvage. Oncogene, 42. pp. 1282-1293. ISSN 0950-9232

Green, A.C. orcid.org/0000-0002-0175-1485, Marttila, P. orcid.org/0000-0002-0115-8067, Kiweler, N. orcid.org/0000-0001-7493-703X et al. (31 more authors) (2023) Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells. Nature Metabolism, 5 (4). pp. 642-659. ISSN 2522-5812

Hanna, B.M.F., Michel, M., Helleday, T. orcid.org/0000-0002-7384-092X et al. (1 more author) (2021) NEIL1 and NEIL2 are recruited as potential backup for OGG1 upon OGG1 depletion or inhibition by TH5487. International Journal of Molecular Sciences, 22 (9). 4542. ISSN 1661-6596

Visnes, T., Benítez-Buelga, C., Cázares-Körner, A. et al. (43 more authors) (2020) Targeting OGG1 arrests cancer cell proliferation by inducing replication stress. Nucleic Acids Research, 48 (21). pp. 12234-12251. ISSN 0305-1048

Rudd, S.G., Gad, H. orcid.org/0000-0001-6530-1443, Sanjiv, K. et al. (7 more authors) (2020) MTH1 inhibitor TH588 disturbs mitotic progression and induces mitosis-dependent accumulation of genomic 8-oxodG. Cancer Research, 80 (17). pp. 3530-3541. ISSN 0008-5472

Rudd, S.G. orcid.org/0000-0002-4368-3855, Gad, H., Amaral, N. et al. (6 more authors) (2019) MTH1 inhibitor TH588 induces mitosis-dependent accumulation of genomic 8-oxodG and disturbs mitotic progression. bioRxiv. (Submitted)

Tepper, S., Mortusewicz, O., Członka, E. et al. (10 more authors) (2019) Restriction of AID activity and somatic hypermutation by PARP-1. Nucleic Acids Research, 47 (14). pp. 7418-7429. ISSN 0305-1048

Visnes, T., Cázares-Körner, A., Hao, W. et al. (37 more authors) (2018) Small-molecule inhibitor of OGG1 suppresses pro-inflammatory gene expression and inflammation. Science, 362 (6416). pp. 834-839. ISSN 0036-8075

Hagenkort, A., Paulin, C.B.J., Desroses, M. et al. (12 more authors) (2017) dUTPase inhibition augments replication defects of 5-Fluorouracil. Oncotarget, 8 (14). pp. 23713-23726.

Sokolova, M., Turunen, M., Mortusewicz, O. et al. (7 more authors) (2017) Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion. Cell Cycle, 16 (2). pp. 189-199. ISSN 1538-4101

Tanikawa, M., Sanjiv, K., Helleday, T. orcid.org/0000-0002-7384-092X et al. (2 more authors) (2016) The spliceosome U2 snRNP factors promote genome stability through distinct mechanisms; transcription of repair factors and R-loop processing. Oncogenesis, 5 (12). e280. ISSN 2157-9024

Herr, P. orcid.org/0000-0003-2945-966X, Lundin, C., Evers, B. et al. (8 more authors) (2015) A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair. Cell Discovery, 1. 15034.

Proceedings Paper

Sanjiv, K., Gad, H., Rudd, S. et al. (15 more authors) (2016) Polymerase kappa determines the sensitivity of MTH1 inhibitors to cisplatin-resistant cell. In: Cancer Research. AACR 107th Annual Meeting 2016, 16-20 Apr 2016, New Orleans, LA, USA. American Association for Cancer Research .