Items where authors include "Middleton, G"

Article

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

Várnai, C, Palles, C, Arnold, R et al. (17 more authors) (2022) Mortality Among Adults With Cancer Undergoing Chemotherapy or Immunotherapy and Infected With COVID-19. JAMA Network Open, 5 (2). e220130. ISSN 2574-3805

Booth, S, Curley, HM, Varnai, C et al. (33 more authors) (2022) Key findings from the UKCCMP cohort of 877 patients with haematological malignancy and COVID-19: disease control as an important factor relative to recent chemotherapy or anti-CD20 therapy. British Journal of Haematology, 196 (4). pp. 892-901. ISSN 0007-1048

Adams, RA, Fisher, DJ, Graham, J et al. (19 more authors) (2021) Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial. Journal of Clinical Oncology. JCO.21.01436-JCO.21.01436. ISSN 0732-183X

Lee, LYW, Cazier, J-B, Starkey, T et al. (37 more authors) (2020) COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study. The Lancet Oncology. ISSN 1470-2045

Pickles, OJ, Lee, LYW, Starkey, T et al. (7 more authors) (2020) Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome? British Journal of Cancer. ISSN 0007-0920

Lee, LYW, Cazier, J-B, Angelis, V et al. (36 more authors) (2020) COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study. The Lancet, 395 (10241). pp. 1919-1926. ISSN 0140-6736

Anil, I, Arnold, R, Benkwitz-Beford, S et al. (27 more authors) (2020) The UK Coronavirus Cancer Monitoring Project: protecting patients with cancer in the era of COVID-19. The Lancet Oncology, 21 (5). pp. 622-624. ISSN 1470-2045

Abbosh, C, Birkbak, NJ, Wilson, GA et al. (425 more authors) (2017) Phylogenetic ctDNA analysis depicts early stage lung cancer evolution. Nature, 545. pp. 446-451. ISSN 0028-0836

Seligmann, JF, Fisher, D, Smith, CG et al. (9 more authors) (2017) Investigating the poor outcomes of BRAF - mutant advanced colorectal cancer: Analysis from 2530 patients in randomised clinical trials. Annals of Oncology, 28 (3). pp. 562-568. ISSN 0923-7534

Middleton, G, Brown, S, Lowe, C et al. (17 more authors) (2013) A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: results of the Panitumumab, Irinotecan & Ciclosporin in COLOrectal cancer therapy trial (PICCOLO). European Journal of Cancer, 49 (16). 3507 - 3516. ISSN 0959-8049

Seymour, MT, Brown, SR, Middleton, G et al. (18 more authors) (2013) Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial. The Lancet Oncology, 14 (8). 749 - 759. ISSN 1470-2045

Proceedings Paper

Richman, SD orcid.org/0000-0003-3993-5041, Adams, R, Brown, E et al. (14 more authors) (2017) FOCUS4: MAMS Trial Design in Action. Early Closure of FOCUS4-D (Pan-HER 1, 2 and 3 Inhibitor Versus Placebo) in Advanced Colorectal Cancer (aCRC) Patients, with Tumours Wildtype (WT) for KRAS, NRAS, bRAF and PIK3CA. In: Journal of Pathology. Belfast Pathology 2017: 10th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 20-23 Jun 2017, Belfast, Northern Ireland, UK. Wiley , S13-S13.