Items where authors include "McGown, A."

Article

Abani, O., Abbas, A., Abbas, F. et al. (8021 more authors) (2025) Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial. eClinicalMedicine, 81. 103080. ISSN 2589-5370

Kempthorne, L., Vaizoglu, D., Cammack, A.J. et al. (27 more authors) (2025) Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo. Nature Communications, 16 (1). 459. ISSN 2041-1723

Burrows, D.J. orcid.org/0000-0002-5833-9379, McGown, A., Abduljabbar, O. et al. (4 more authors) (2024) RAN translation of C9orf72-related dipeptide repeat proteins in zebrafish recapitulates hallmarks of amyotrophic lateral sclerosis and identifies hypothermia as a therapeutic strategy. Annals of Neurology, 96 (6). pp. 1058-1069. ISSN 0364-5134

Faust, S.N., Haynes, R., Jones, C.E. et al. (7370 more authors) (2024) Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet Child & Adolescent Health, 8 (3). pp. 190-200. ISSN 2352-4642

Abani, O., Abbas, A., Abbas, F. et al. (7989 more authors) (2023) Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet Diabetes & Endocrinology, 11 (12). pp. 905-914. ISSN 2213-8587

Abani, O., Abbas, A., Abbas, F. et al. (8104 more authors) (2023) Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 401 (10387). pp. 1499-1507. ISSN 0140-6736

Boddy, S., Islam, M. orcid.org/0000-0002-2296-0120, Moll, T. et al. (17 more authors) (2022) Unbiased metabolome screen leads to personalized medicine strategy for amyotrophic lateral sclerosis. Brain Communications, 4 (2). fcac069. ISSN 2632-1297

Burrows, D.J. orcid.org/0000-0002-5833-9379, McGown, A. orcid.org/0000-0002-3213-1895, Jain, S.A. et al. (4 more authors) (2019) Animal models of multiple sclerosis: From rodents to zebrafish. Multiple Sclerosis Journal, 25 (3). pp. 306-324. ISSN 1352-4585

Shaw, M.P., Higginbottom, A. orcid.org/0000-0002-3246-6695, McGown, A. et al. (5 more authors) (2018) Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features. Acta Neuropathologica Communications, 6 (1). 125. ISSN 2051-5960

Chhabria, K., Plant, K., Bandmann, O. et al. (11 more authors) (2018) The effect of hyperglycemia on neurovascular coupling and cerebrovascular patterning in zebrafish. Journal of Cerebral Blood Flow and Metabolism, 40 (2). 298 -313. ISSN 0271-678X

McGown, A. orcid.org/0000-0002-3213-1895 and Stopford, M.J. orcid.org/0000-0002-1298-4102 (2018) High-throughput drug screens for amyotrophic lateral sclerosis drug discovery. Expert Opinion on Drug Discovery, 13 (11). pp. 1015-1025. ISSN 1746-0441

McGown, A., Shaw, D.P.J. and Ramesh, T. (2016) ZNStress: A high-throughput drug screening protocol for identification of compounds modulating neuronal stress in the transgenic mutant sod1G93R zebrafish model of amyotrophic lateral sclerosis. Molecular Neurodegeneration, 11 (1). 56. ISSN 1750-1326

McGown, A., McDearmid, J.R., Panagiotaki, N. et al. (7 more authors) (2012) Early interneuron dysfunction in ALS: Insights from a mutant sod1 zebrafish model. Annals of Neurology, 73 (2). 246 - 258. ISSN 0364-5134

Prendiville, J., Crowther, D., Thatcher, N. et al. (8 more authors) (1993) A phase-I study of intravenous bryostatin-1 in patients with advanced cancer. British Journal of Cancer, 68 (2). 418 - 424. ISSN 0007-0920