Items where authors include "Koolmeister, T."

Article

Scaletti, E.R., Unterlass, J.E., Almlöf, I. et al. (7 more authors) (2024) Kinetic and structural characterization of NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis. The FEBS Journal, 291 (19). pp. 4301-4322. ISSN 1742-464X

Zhang, S.M., Paulin, C.B.J., Shu, H. et al. (24 more authors) (2024) Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel. iScience, 27 (2). 108907. ISSN 2589-0042

Odell, L.R. orcid.org/0000-0001-7658-5103, Skillinghaug, B. orcid.org/0000-0002-8014-5757, Matt, C. et al. (7 more authors) (2023) Synthesis of substituted indazole acetic acids by N−N bond forming reactions. European Journal of Organic Chemistry, 26 (29). e202300291. ISSN 1434-193X

Sanjiv, K., Calderón-Montaño, J.M., Pham, T.M. et al. (29 more authors) (2021) MTH1 inhibitor TH1579 induces oxidative DNA damage and mitotic arrest in acute myeloid leukemia. Cancer Research, 81 (22). pp. 5733-5744. ISSN 0008-5472

Rehling, D., Zhang, S.M., Jemth, A.-S. et al. (15 more authors) (2021) Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity. Journal of Biological Chemistry, 296. 100568. ISSN 0021-9258

Visnes, T., Benítez-Buelga, C., Cázares-Körner, A. et al. (43 more authors) (2020) Targeting OGG1 arrests cancer cell proliferation by inducing replication stress. Nucleic Acids Research, 48 (21). pp. 12234-12251. ISSN 0305-1048

Zhang, S.M., Desroses, M., Hagenkort, A. et al. (34 more authors) (2020) Development of a chemical probe against NUDT15. Nature Chemical Biology, 16 (10). pp. 1120-1128. ISSN 1552-4450

Visnes, T., Cázares-Körner, A., Hao, W. et al. (37 more authors) (2018) Small-molecule inhibitor of OGG1 suppresses pro-inflammatory gene expression and inflammation. Science, 362 (6416). pp. 834-839. ISSN 0036-8075

Einarsdottir, B.O., Karlsson, J., Söderberg, E.M.V. et al. (16 more authors) (2018) A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma. Cell Death and Disease, 9 (8). 810. ISSN 2041-4889

Hagenkort, A., Paulin, C.B.J., Desroses, M. et al. (12 more authors) (2017) dUTPase inhibition augments replication defects of 5-Fluorouracil. Oncotarget, 8 (14). pp. 23713-23726.

Gao, C., Bourke, E., Scobie, M. et al. (6 more authors) (2014) Rational design and validation of a Tip60 histone acetyltransferase inhibitor. Scientific Reports, 4. 5372.

Proceedings Paper

Walter, M. orcid.org/0000-0003-3241-522X, Homan, E., Koolmeister, T. et al. (3 more authors) (2021) Development of small molecule NUDT22 inhibitors for uses in cancer. In: Medical Sciences Forum. IECC 2021: 1st International Electronic Conference on Cancers, 01-14 Feb 2021, Online. MDPI .

Sanjiv, K., Gad, H., Rudd, S. et al. (15 more authors) (2016) Polymerase kappa determines the sensitivity of MTH1 inhibitors to cisplatin-resistant cell. In: Cancer Research. AACR 107th Annual Meeting 2016, 16-20 Apr 2016, New Orleans, LA, USA. American Association for Cancer Research .