Items where authors include "Hubbard, Roderick E."

Article

FitzGerald, Edward A., Vagrys, Darius, Opassi, Giulia et al. (13 more authors) (2023) Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors. SLAS Discovery. ISSN 2472-5552

Jones, S. Paul, Firth, James D., Wheldon, Mary C. et al. (11 more authors) (2022) Exploration of piperidine 3D fragment chemical space:synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates. RSC Medicinal Chemistry. pp. 1614-1620. ISSN 2632-8682

Baker, Lisa M., Aimon, Anthony, Murray, James B. et al. (7 more authors) (2020) Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures. Communications Chemistry. 122. ISSN 2399-3669

Makraki, Eleni, Darby, John F. orcid.org/0000-0003-2754-6348, Carneiro, Marta G. et al. (6 more authors) (2020) Fragment-derived modulators of an industrial β-glucosidase. The Biochemical journal. pp. 4383-4395. ISSN 1470-8728

Darby, John F. orcid.org/0000-0003-2754-6348, Gilio, Amelia K., Piniello, Beatriz et al. (6 more authors) (2020) Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase v. ACS Catalysis. pp. 8590-8596. ISSN 2155-5435

Vagrys, Darius, Davidson, James, Chen, Ijen et al. (2 more authors) (2020) Exploring idp–ligand interactions:Tau k18 as a test case. International Journal of Molecular Sciences. 5257. ISSN 1422-0067

Makraki, Eleni, Carneiro, Marta G., Heyam, Alex et al. (3 more authors) (2020) Correction to:1H, 13C, 15N backbone and IVL methyl group resonance assignment of the fungal β-glucosidase from Trichoderma reesei (Biomolecular NMR Assignments, (2020), 10.1007/s12104-020-09959-2). Biomolecular NMR assignments. ISSN 1874-270X

Makraki, Eleni, Carneiro, Marta G., Heyam, Alex et al. (3 more authors) (2020) 1H, 13C, 15N backbone and IVL methyl group resonance assignment of the fungal β-glucosidase from Trichoderma reesei. Biomolecular NMR assignments. ISSN 1874-270X

Murray, James B., Davidson, James, Chen, Ijen et al. (21 more authors) (2019) Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1. ACS Omega. pp. 8892-8906.

Rachman, Moira M., Barril, Xavier and Hubbard, Roderick E. orcid.org/0000-0002-8233-7461 (2018) Predicting how drug molecules bind to their protein targets. Current Opinion in Pharmacology. pp. 34-39. ISSN 1471-4892

Romasanta, Angelo K.S., van der Sijde, Peter, Hellsten, Iina et al. (4 more authors) (2018) When fragments link:a bibliometric perspective on the development of fragment-based drug discovery. Drug discovery today. ISSN 1359-6446

Darby, John F. orcid.org/0000-0003-2754-6348, Atobe, Masakazu, Firth, James D. et al. (4 more authors) (2017) Increase of enzyme activity through specific covalent modification with fragments. Chemical Science. pp. 7772-7779. ISSN 2041-6539

Williamson, Douglas S., Smith, Garrick P., Acheson-Dossang, Pamela et al. (20 more authors) (2017) Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1). JOURNAL OF MEDICINAL CHEMISTRY. pp. 8945-8962. ISSN 0022-2623