Items where authors include "Gad, H."

Article

Shen, J., Guillén Mancina, E., Chen, S. et al. (5 more authors) (2024) Mitotic MTH1 inhibitor TH1579 induces PD-L1 expression and inflammatory response through the cGAS-STING pathway. Oncogenesis, 13. 17. ISSN 2157-9024

Ponirakis, G., Ghandi, R., Ahmed, A. et al. (17 more authors) (2022) Abnormal corneal nerve morphology and brain volume in patients with schizophrenia. Scientific Reports, 12 (1). 1870.

Sanjiv, K., Calderón-Montaño, J.M., Pham, T.M. et al. (29 more authors) (2021) MTH1 inhibitor TH1579 induces oxidative DNA damage and mitotic arrest in acute myeloid leukemia. Cancer Research, 81 (22). pp. 5733-5744. ISSN 0008-5472

Khan, A., Menon, A., Akhtar, N. et al. (16 more authors) (2021) Corneal nerve loss as a surrogate marker for poor pial collaterals in patients with acute ischemic stroke. Scientific Reports, 11 (1). 19718.

Zhao, Z., Gad, H. orcid.org/0000-0001-6530-1443, Benitez-Buelga, C. et al. (8 more authors) (2021) NEIL3 prevents senescence in hepatocellular carcinoma by repairing oxidative lesions at telomeres during mitosis. Cancer Research, 81 (15). pp. 4079-4093. ISSN 0008-5472

Oksvold, M.P., Berglund, U.W., Gad, H. orcid.org/0000-0001-6530-1443 et al. (11 more authors) (2021) Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma. Scientific Reports, 11 (1). 6317.

Baquero, J.M., Benítez-Buelga, C., Rajagopal, V. et al. (13 more authors) (2021) Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects. Scientific Reports, 11 (1). 3490.

Visnes, T., Benítez-Buelga, C., Cázares-Körner, A. et al. (43 more authors) (2020) Targeting OGG1 arrests cancer cell proliferation by inducing replication stress. Nucleic Acids Research, 48 (21). pp. 12234-12251. ISSN 0305-1048

Rudd, S.G., Gad, H. orcid.org/0000-0001-6530-1443, Sanjiv, K. et al. (7 more authors) (2020) MTH1 inhibitor TH588 disturbs mitotic progression and induces mitosis-dependent accumulation of genomic 8-oxodG. Cancer Research, 80 (17). pp. 3530-3541. ISSN 0008-5472

Das, I., Gad, H., Bräutigam, L. et al. (9 more authors) (2020) AXL and CAV-1 play a role for MTH1 inhibitor TH1579 sensitivity in cutaneous malignant melanoma. Cell Death & Differentiation, 27. pp. 2081-2098. ISSN 1350-9047

Rudd, S.G. orcid.org/0000-0002-4368-3855, Gad, H., Amaral, N. et al. (6 more authors) (2019) MTH1 inhibitor TH588 induces mitosis-dependent accumulation of genomic 8-oxodG and disturbs mitotic progression. bioRxiv. (Submitted)

Hua, X., Sanjiv, K., Gad, H. et al. (11 more authors) (2019) Karonudib is a promising anticancer therapy in hepatocellular carcinoma. Therapeutic Advances in Medical Oncology, 11. ISSN 1758-8359

Pudelko, L., Rouhi, P., Sanjiv, K. et al. (10 more authors) (2017) Glioblastoma and glioblastoma stem cells are dependent on functional MTH1. Oncotarget, 8 (49). pp. 94671-84684.

Rassoolzadeh, H., Böhm, S., Hedström, E. et al. (4 more authors) (2016) Overexpression of the scaffold WD40 protein WRAP53β enhances the repair of and cell survival from DNA double-strand breaks. Cell Death & Disease, 7 (6). e2267.

Carter, M., Jemth, A.-S., Hagenkort, A. et al. (10 more authors) (2015) Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2. Nature Communications, 6. 7871.

Proceedings Paper

Sanjiv, K., Gad, H., Rudd, S. et al. (15 more authors) (2016) Polymerase kappa determines the sensitivity of MTH1 inhibitors to cisplatin-resistant cell. In: Cancer Research. AACR 107th Annual Meeting 2016, 16-20 Apr 2016, New Orleans, LA, USA. American Association for Cancer Research .