Items where authors include "Fry, AM"

Article

Papageorgiou, S, Pashley, SL, O’Regan, L et al. (3 more authors) (2022) Alternative Treatment Options to ALK Inhibitor Monotherapy for EML4-ALK-Driven Lung Cancer. Cancers, 14 (14). 3452. ISSN 2072-6694

Lucken, K, O'Regan, L, Choi, J et al. (5 more authors) (2022) EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity. Molecular Cancer Research, 20 (6). pp. 854-866. ISSN 1541-7786

Lucken, K, O'Regan, L, Choi, J et al. (5 more authors) (2022) EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity. Molecular Cancer Research, 20 (6). pp. 854-866. ISSN 1541-7786

Sampson, J orcid.org/0000-0002-0147-6014, Ju, H-M, Song, J-Y et al. (3 more authors) (2022) A Polytherapy Strategy Using Vincristine and ALK Inhibitors to Sensitise EML4-ALK-Positive NSCLC. Cancers, 14 (3). 779. ISSN 2072-6694

Sampson, J orcid.org/0000-0002-0147-6014, Richards, MW orcid.org/0000-0003-1108-2825, Choi, J et al. (2 more authors) (2021) Phase‐separated foci of EML4‐ALK facilitate signalling and depend upon an active kinase conformation. EMBO Reports, 22 (12). e53693. ISSN 1469-221X

Matheson, CJ, Coxon, CR, Bayliss, R orcid.org/0000-0003-0604-2773 et al. (13 more authors) (2020) 2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase. RSC Medicinal Chemistry, 11 (6). pp. 707-731. ISSN 2632-8682

O'Regan, L, Barone, G, Adib, R et al. (10 more authors) (2020) EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7. Journal of Cell Science. jcs.241505. jcs.241505-jcs.241505. ISSN 0021-9533

Adib, R, Montgomery, JM, Atherton, J et al. (8 more authors) (2019) Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression. Science signaling, 12 (594). ARTN eaaw2939. ISSN 1945-0877

Mukherjee, M orcid.org/0000-0002-3615-7574, Sabir, S, O'Regan, L et al. (8 more authors) (2018) Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release. Science signaling, 11 (543). eaao2464. ISSN 1945-0877

Fry, AM, Bayliss, R orcid.org/0000-0003-0604-2773 and Roig, J (2017) Mitotic regulation by NEK kinase networks. Frontiers in Cell and Developmental Biology, 5 (DEC). 102. ISSN 2296-634X

Sampson, J, O'Regan, L, Dyer, MJS et al. (2 more authors) (2017) Hsp72 and Nek6 cooperate to cluster amplified centrosomes in cancer cells. Cancer Research, 77 (18). pp. 4785-4796. ISSN 0008-5472

Fry, AM, Sampson, J orcid.org/0000-0002-0147-6014, Shak, C et al. (1 more author) (2017) Recent advances in pericentriolar material organization: ordered layers and scaffolding gels. F1000Research, 6. 1622. ISSN 2046-1402

Coxon, CR, Wong, C, Bayliss, RWA orcid.org/0000-0003-0604-2773 et al. (14 more authors) (2017) Structure-guided design of purine-based probes for selective Nek2 inhibition. Oncotarget, 8 (12). pp. 19089-19124. ISSN 1949-2553

Mitcheson, DF, Bottrill, AR, Carr, K et al. (8 more authors) (2016) A new tool for the chemical genetic investigation of the Plasmodium falciparum Pfnek-2 NIMA-related kinase. Malaria Journal, 15. 535. ISSN 1475-2875

Fry, AM, O'Regan, L, Montgomery, J et al. (2 more authors) (2016) EML proteins in microtubule regulation and human disease. Biochemical Society Transactions, 44 (5). pp. 1281-1288. ISSN 0300-5127

Bayliss, R orcid.org/0000-0003-0604-2773, Choi, J, Fennell, DA et al. (2 more authors) (2016) Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugs. Cellular and Molecular Life Sciences, 73 (6). pp. 1209-1224. ISSN 1420-682X

Proceedings Paper

Mukherjee, M, Sampson, J, Sabir, S et al. (8 more authors) (2017) Mitotic phosphorylation of Hsp72 uncouples ATP binding from substrate release and clusters amplified centrosomes in cancer cells. In: Molecular Biology of the Cell. ASCB | EMBO 2017 Meeting, 02-06 Dec 2017, Philadelphia, PA. American Society for Cell Biology , T-361-T-362.