Items where authors include "Foster, R"

Article

Parsonage, G, Cuthbertson, K, Endesh, N et al. (16 more authors) (2023) Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1. British Journal of Pharmacology, 180 (16). pp. 2039-2063. ISSN 0007-1188

Hardy, LJ, Bohinc, D, Bane, KL et al. (9 more authors) (2023) Glycated albumin modulates the contact system with implications for the kallikrein-kinin and intrinsic coagulation systems. Journal of Thrombosis and Haemostasis, 21 (4). pp. 814-827. ISSN 1538-7933

Masson, B, Le Ribeuz, H, Sabourin, J et al. (16 more authors) (2022) Orai1 Inhibitors as Potential Treatments for Pulmonary Arterial Hypertension. Circulation Research, 131 (9). e102-e119.. ISSN 0009-7330

Heal, SL, Hardy, LJ, Wilson, CL et al. (4 more authors) (2022) Novel interaction of properdin and coagulation factor XI: Crosstalk between complement and coagulation. Research and Practice in Thrombosis and Haemostasis, 6 (4). e12715. ISSN 2475-0379

Xu, Y orcid.org/0000-0002-8389-4120, Maya-Martinez, R orcid.org/0000-0002-7371-8051, Guthertz, N orcid.org/0000-0001-7247-1176 et al. (6 more authors) (2022) Tuning the rate of aggregation of hIAPP into amyloid using smallmolecule modulators of assembly. Nature Communications, 13. 1040. ISSN 2041-1723

Foster, H, Wilson, C, Gauer, JS orcid.org/0000-0002-0835-639X et al. (8 more authors) (2022) A Comparative Assessment Study of Known Small-molecule GPVI Modulators. ACS Medicinal Chemistry Letters, 13 (2). pp. 171-181. ISSN 1948-5875

Shawer, H, Norman, K, Cheng, CW orcid.org/0000-0002-2873-0828 et al. (3 more authors) (2021) ORAI1 Ca2+ channel as a therapeutic target in pathological vascular remodelling. Frontiers in Cell and Developmental Biology, 9. 653812. ISSN 2296-634X

Singh, R, Li, Z, Foster, R orcid.org/0000-0002-2361-3884 et al. (1 more author) (2021) A Classroom-Based Activity to Teach Students How to Apply Organic Chemistry Theory to Design Experiments. Journal of Chemical Education, 98 (2). pp. 515-520. ISSN 0021-9584

Mills, B, Isaac, RE orcid.org/0000-0003-4792-6559 and Foster, R orcid.org/0000-0002-2361-3884 (2021) Metalloaminopeptidases of the Protozoan Parasite Plasmodium falciparum as Targets for the Discovery of Novel Antimalarial Drugs. Journal of Medicinal Chemistry. ISSN 0022-2623

Read, C, Nyimanu, D, Yang, P et al. (7 more authors) (2021) The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis In Vitro and Induces Vasodilatation Without Desensitisation In Vivo. Frontiers in Pharmacology, 11. 588669. ISSN 1663-9812

Kearney, KJ orcid.org/0000-0002-0387-6812, Butler, J, Posada, OM et al. (10 more authors) (2021) Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI. Proceedings of the National Academy of Sciences, 118 (3). e201481011. ISSN 0027-8424

Foster, H, Wilson, C, Philippou, H et al. (1 more author) (2020) Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. Journal of Medicinal Chemistry, 63 (21). pp. 12213-12242. ISSN 0022-2623

Shaw, J, Gosein, R, Kalita, MM et al. (19 more authors) (2020) Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy. eLife, 9. e52555.

Gallardo, R orcid.org/0000-0003-1584-3564, Iadanza, MG, Xu, Y et al. (4 more authors) (2020) Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly. Nature Structural & Molecular Biology, 27 (11). pp. 1048-1056. ISSN 1545-9993

Scott, C, Kankanala, J, Foster, TL et al. (20 more authors) (2020) Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza. PLOS Pathogens, 16 (8). e1008716. ISSN 1553-7366

Bartoli, F orcid.org/0000-0001-9487-9551, Bailey, MA orcid.org/0000-0001-5038-1970, Rode, B et al. (23 more authors) (2020) Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload. Circulation, 141 (3). pp. 199-216. ISSN 0009-7322

Blythe, NM, Muraki, K, Ludlow, MJ et al. (12 more authors) (2019) Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion. Journal of Biological Chemistry, 294 (46). pp. 17395-17408. ISSN 0021-9258

Deivasikamani, V, Dhayalan, S, Abudushalamu, Y et al. (12 more authors) (2019) Piezo1 channel activation mimics high glucose as a stimulator of insulin release. Scientific Reports, 9. 16876. ISSN 2045-2322

Schepaschenko, D, Chave, J, Phillips, OL orcid.org/0000-0002-8993-6168 et al. (140 more authors) (2019) The Forest Observation System, building a global reference dataset for remote sensing of forest biomass. Scientific Data, 6. 198. ISSN 2052-4463

Danielson, DL, Akindele, OA, Askins, M et al. (67 more authors) (2019) Directionally accelerated detection of an unknown second reactor with antineutrinos for mid-field nonproliferation monitoring. arXiv. (Submitted)

Duncan, JA orcid.org/0000-0002-0044-4977, Foster, R orcid.org/0000-0002-2361-3884 and Kwok, JCF orcid.org/0000-0002-9798-9083 (2019) The Potential of Memory Enhancement through Perineuronal Net Modulation. British Journal of Pharmacology, 176 (18). pp. 3611-3621. ISSN 0007-1188

Wetherill, LF, Wasson, CW, Swinscoe, G orcid.org/0000-0003-0595-3460 et al. (4 more authors) (2018) Alkyl-Imino sugars inhibit the pro-oncogenic ion channel function of human papillomavirus (HPV) E5. Antiviral Research, 158. pp. 113-121. ISSN 0166-3542

Easton, V, McPhillie, M, Garcia-Dorival, I et al. (5 more authors) (2018) Identification of a small molecule inhibitor of Ebolavirus genome replication and transcription using in silico screening. Antiviral Research, 156. pp. 46-54. ISSN 0166-3542

Rubaiy, HN orcid.org/0000-0002-1489-5576, Ludlow, MJ, Siems, K et al. (5 more authors) (2018) Tonantzitlolone is a Nanomolar Potency Activator of TRPC1/4/5 Channels. British Journal of Pharmacology, 175 (16). pp. 3361-3368. ISSN 0007-1188

Evans, EL, Cuthbertson, K, Endesh, N et al. (8 more authors) (2018) Yoda1 analogue (Dooku1) which antagonizes Yoda1‐evoked activation of Piezo1 and aortic relaxation. British Journal of Pharmacology, 175 (10). pp. 1744-1759. ISSN 0007-1188

Ozsvari, B, Bonuccelli, G, Sanchez-Alvarez, R et al. (3 more authors) (2017) Targeting flavin-containing enzymes eliminates cancer stem cells (CSCs), by inhibiting mitochondrial respiration: Vitamin B2 (Riboflavin) in cancer therapy. Aging, 9 (12). pp. 2610-2628. ISSN 1945-4589

Muraki, K, Ohnishi, K, Takezawa, A et al. (10 more authors) (2017) Na⁺ entry through heteromeric TRPC4/C1 channels mediates (-)Englerin A-induced cytotoxicity in synovial sarcoma cells. Scientific Reports, 7 (1). 16988. ISSN 2045-2322

Ozsvari, B, Sotgia, F, Simmons, K et al. (3 more authors) (2017) Mitoketoscins: Novel mitochondrial inhibitors for targeting ketone metabolism in cancer stem cells (CSCs). Oncotarget, 8 (45). pp. 78340-78350. ISSN 1949-2553

Rode, B, Shi, J, Endesh, N et al. (22 more authors) (2017) Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance. Nature Communications, 8. 350. ISSN 2041-1723

Man, K, Jiang, L-H orcid.org/0000-0001-6398-0411, Foster, R et al. (1 more author) (2017) Immunological Responses to Total Hip Arthroplasty. Journal of Functional Biomaterials, 8 (3). 33. ISSN 2079-4983

Ozsvari, B, Fiorillo, M, Bonuccelli, G et al. (6 more authors) (2017) Mitoriboscins: Mitochondrial-based therapeutics targeting cancer stem cells (CSCs), bacteria and pathogenic yeast. Oncotarget, 8 (40). pp. 67457-67472. ISSN 1949-2553

Rubaiy, HN orcid.org/0000-0002-1489-5576, Ludlow, MJ, Henrot, M et al. (18 more authors) (2017) Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels. Journal of Biological Chemistry, 292 (20). pp. 8158-8173. ISSN 0021-9258

Bridge, K, Revill, C, Macrae, F et al. (8 more authors) (2017) Inhibition of plasmin-mediated TAFI activation may affect development but not progression of abdominal aortic aneurysms. PLOS ONE, 12 (5). e0177117. ISSN 1932-6203

Schumann, S orcid.org/0000-0002-0227-1360, Jackson, BR, Yule, I et al. (4 more authors) (2016) Targeting the ATP-dependent formation of herpesvirus ribonucleoprotein particle assembly as an antiviral approach. Nature Microbiology, 2. 16201.

Walter, S, Bollenbach, A, Doerrbecker, J et al. (11 more authors) (2016) Ion-channel function and cross-species determinants in viral assembly of nonprimate hepacivirus p7. Journal of Virology, 90 (10). pp. 5075-5089. ISSN 0022-538X

Fisher, M, Williamson, DJ, Burslem, GM et al. (11 more authors) (2015) Trivalent Gd-DOTA reagents for modification of proteins. RSC Advances, 5 (116). 96194 - 96200. ISSN 2046-2069

Li, J, Bruns, A-F orcid.org/0000-0002-6970-4036, Hou, B et al. (18 more authors) (2015) Orai3 Surface Accumulation and Calcium Entry Evoked by Vascular Endothelial Growth Factor. Arteriosclerosis, Thrombosis, and Vascular Biology, 35 (9). pp. 1987-1994. ISSN 1079-5642

Firth, JD, Zhang, R, Morgentin, R et al. (6 more authors) (2015) Exploitation of the Ugi-Joullie Reaction in the Synthesis of Libraries of Drug-Like Bicyclic Hydantoins. SYNTHESIS, 47 (16). pp. 2391-2406. ISSN 0039-7881

Colomer, I, Adeniji, O, Burslem, GM et al. (7 more authors) (2015) Aminomethylhydroxylation of alkenes: Exploitation in the synthesis of scaffolds for small molecule libraries. Bioorganic and Medicinal Chemistry, 23 (11). pp. 2736-2740. ISSN 0968-0896

Craven, P orcid.org/0000-0002-7617-132X, Aimon, A, Dow, M et al. (8 more authors) (2015) Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries. Bioorganic and Medicinal Chemistry, 23 (11). pp. 2629-2635. ISSN 0968-0896

Foster, TL, Thompson, GS, Kalverda, AP et al. (13 more authors) (2014) Structure-guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion release. Hepatology, 59 (2). pp. 408-422. ISSN 0270-9139

Wetherill, LF, Holmes, K, Verow, M et al. (9 more authors) (2012) High-risk papillomavirus E5 oncoprotein displays channel-forming activity sensitive to small molecule inhibitors. Journal of Virology, 86 (9). pp. 5341-5351. ISSN 0022-538X

Li, J, McKeown, L orcid.org/0000-0003-2326-7595, Ojelabi, O et al. (5 more authors) (2011) Nanomolar potency and selectivity of a Ca 2+ release-activated Ca 2+ channel inhibitor against store-operated Ca 2+ entry and migration of vascular smooth muscle cells. British Journal of Pharmacology, 164 (2). pp. 382-393. ISSN 0007-1188

Dowding, D, Randell, R, Mitchell, N et al. (4 more authors) (2009) Experience and nurses use of computerised decision support systems. Connecting Health and Humans (Proceedings of NI2009), 146 (Studie). 506 - 510 . ISSN 0926-9630