Items where authors include "Fennell, D.A."

Article

Bentham, R., Jones, T.P. orcid.org/0000-0003-2748-0780, Black, J.R.M. orcid.org/0000-0001-5598-7752 et al. (327 more authors) (2025) ImmuneLENS characterizes systemic immune dysregulation in aging and cancer. Nature Genetics, 57. pp. 694-705. ISSN 1061-4036

Biswas, D. orcid.org/0000-0001-9141-5188, Liu, Y.-H. orcid.org/0009-0001-1508-5276, Herrero, J. orcid.org/0000-0001-7313-717X et al. (267 more authors) (2025) Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma. Nature Cancer, 6. pp. 86-101. ISSN 2662-1347

Black, J.R.M. orcid.org/0000-0001-5598-7752, Bartha, G., Abbott, C.W. et al. (277 more authors) (2025) Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma. Nature Medicine, 31 (1). pp. 70-76. ISSN 1078-8956

Puttick, C. orcid.org/0009-0006-3022-8737, Jones, T.P. orcid.org/0000-0003-2748-0780, Leung, M.M. orcid.org/0000-0001-9555-1080 et al. (279 more authors) (2024) MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution. Nature Genetics, 56. pp. 2121-2131. ISSN 1061-4036

Hobor, S., Al Bakir, M. orcid.org/0000-0002-0846-8332, Hiley, C.T. et al. (292 more authors) (2024) Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature Communications, 15. 4871. ISSN 2041-1723

Hynds, R.E. orcid.org/0000-0002-2170-8791, Huebner, A. orcid.org/0000-0001-8009-4999, Pearce, D.R. orcid.org/0000-0001-8443-2924 et al. (274 more authors) (2024) Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models. Nature Communications, 15 (1). 4653. ISSN 2041-1723

Pan, X., AbdulJabbar, K. orcid.org/0000-0002-4411-4435, Coelho-Lima, J. et al. (276 more authors) (2024) The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma. Nature Cancer, 5 (2). pp. 347-363. ISSN 2662-1347

Ng, K.W., Boumelha, J., Enfield, K.S.S. orcid.org/0000-0002-4551-6073 et al. (328 more authors) (2023) Antibodies against endogenous retroviruses promote lung cancer immunotherapy. Nature, 616. pp. 563-573. ISSN 0028-0836

Martínez-Ruiz, C. orcid.org/0000-0002-4817-0565, Black, J.R.M., Puttick, C. et al. (294 more authors) (2023) Genomic–transcriptomic evolution in lung cancer and metastasis. Nature, 616. pp. 543-552. ISSN 0028-0836

Abbosh, C. orcid.org/0000-0002-8983-1382, Frankell, A.M. orcid.org/0000-0002-0341-7878, Harrison, T. et al. (303 more authors) (2023) Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA. Nature, 616 (7957). pp. 553-562. ISSN 0028-0836

Frankell, A.M. orcid.org/0000-0002-0341-7878, Dietzen, M. orcid.org/0000-0002-6853-7563, Al Bakir, M. orcid.org/0000-0002-0846-8332 et al. (284 more authors) (2023) The evolution of lung cancer and impact of subclonal selection in TRACERx. Nature, 616. pp. 525-533. ISSN 0028-0836

Al Bakir, M. orcid.org/0000-0002-0846-8332, Huebner, A. orcid.org/0000-0001-8009-4999, Martínez-Ruiz, C. orcid.org/0000-0002-4817-0565 et al. (283 more authors) (2023) The evolution of non-small cell lung cancer metastases in TRACERx. Nature, 616. pp. 534-542. ISSN 0028-0836

Hill, W., Lim, E.L., Weeden, C.E. et al. (323 more authors) (2023) Lung adenocarcinoma promotion by air pollutants. Nature, 616 (7955). pp. 159-167. ISSN 0028-0836

Al-Sawaf, O. orcid.org/0000-0001-9895-0570, Weiss, J., Skrzypski, M. et al. (302 more authors) (2023) Body composition and lung cancer-associated cachexia in TRACERx. Nature Medicine, 29 (4). pp. 846-858. ISSN 1078-8956

Karasaki, T. orcid.org/0000-0001-6863-2360, Moore, D.A. orcid.org/0000-0002-6296-1312, Veeriah, S. et al. (288 more authors) (2023) Evolutionary characterization of lung adenocarcinoma morphology in TRACERx. Nature Medicine, 29 (4). pp. 833-845. ISSN 1078-8956

Fennell, D.A. orcid.org/0000-0001-7373-1312, Porter, C., Lester, J. et al. (8 more authors) (2022) Olaparib maintenance versus placebo monotherapy in patients with advanced non-small cell lung cancer (PIN): a multicentre, randomised, controlled, phase 2 trial. eClinicalMedicine, 52. 101595. ISSN 2589-5370

Fennell, D.A. orcid.org/0000-0001-7373-1312, Porter, C., Lester, J. et al. (14 more authors) (2022) Active symptom control with or without oral vinorelbine in patients with relapsed malignant pleural mesothelioma (VIM): A randomised, phase 2 trial. eClinicalMedicine, 48. 101432. ISSN 2589-5370

Fennell, D.A., Griffiths, G., Ottensmeier, C. et al. (4 more authors) (2022) CONFIRM trial: what is the real efficacy of second-line immunotherapy in mesothelioma? – Authors' reply. The Lancet Oncology, 23 (1). e14-e15. ISSN 1470-2045

Fennell, D.A., Ewings, S., Ottensmeier, C. et al. (36 more authors) (2021) Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial. The Lancet Oncology, 22 (11). pp. 1530-1540. ISSN 1470-2045

Fennell, D.A., Danson, S. orcid.org/0000-0002-3593-2890, Woll, P.J. orcid.org/0000-0002-1118-0831 et al. (9 more authors) (2020) Ganetespib in combination with pemetrexed-platinum chemotherapy in patients with pleural Mesothelioma (MESO-02) : a phase Ib trial. Clinical Cancer Research, 26 (18). pp. 4748-4755. ISSN 1078-0432

O'Regan, L., Barone, G., Adib, R. et al. (10 more authors) (2020) EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7. Journal of Cell Science, 133 (9). jcs.241505. ISSN 0021-9533

Woolhouse, I., Bishop, L., Darlison, L. et al. (14 more authors) (2019) BTS guideline for the investigation and management of malignant pleural mesothelioma. BMJ Open Respiratory Research, 5 (1). e000266. ISSN 2052-4439

Fennell, D.A., Kirkpatrick, E., Cozens, K. et al. (13 more authors) (2018) CONFIRM: a double-blind, placebo controlled phase III clinical trial investigating the effect of nivolumab in patients with relapsed mesothelioma: study protocol for a randomised controlled trial. TRIALS, 19. 233. ISSN 1745-6215

Woolhouse, I., Bishop, L., Darlison, L. et al. (14 more authors) (2018) British Thoracic Society Guideline for the investigation and management of malignant pleural mesothelioma. Thorax, 73 (Suppl 1). i1-i30. ISSN 0040-6376