Items where authors include "Fagan, R.P."

Article

Wilson, J.S. orcid.org/0000-0002-6967-0809, Fortier, L.-C. orcid.org/0000-0003-1950-763X, Fagan, R.P. orcid.org/0000-0002-8704-4828 et al. (1 more author) (2025) Molecular mechanism of bacteriophage contraction structure of an S-layer–penetrating bacteriophage. Life Science Alliance, 8 (6). e202403088. ISSN 2575-1077

Buddle, J.E., Thompson, L.M., Williams, A.S. et al. (6 more authors) (2024) Identification of pathways to high-level vancomycin resistance in Clostridioides difficile that incur high fitness costs in key pathogenicity traits. PLOS Biology, 22 (8). e3002741. ISSN 1545-7885

Galley, N.F. orcid.org/0000-0001-7630-2601, Greetham, D. orcid.org/0000-0003-1222-4258, Alamán-Zárate, M.G. orcid.org/0009-0007-0587-534X et al. (11 more authors) (2024) Clostridioides difficile canonical L,D-transpeptidases catalyze a novel type of peptidoglycan cross-links and are not required for beta-lactam resistance. Journal of Biological Chemistry, 300 (1). 105529. ISSN 0021-9258

Ormsby, M.J., Vaz, F., Kirk, J.A. et al. (8 more authors) (2023) An intact S-layer is advantageous to Clostridioides difficile within the host. PLOS Pathogens, 19 (6). e1011015. ISSN 1553-7374

Royer, A.L.M., Umansky, A.A., Allen, M.-M. et al. (7 more authors) (2023) Clostridioides difficile S-layer protein A (SlpA) serves as a general phage receptor. Microbiology Spectrum, 11 (2). e03894-22. ISSN 2165-0497

Buddle, J.E. and Fagan, R.P. orcid.org/0000-0002-8704-4828 (2023) Pathogenicity and virulence of Clostridioides difficile. Virulence, 14 (1). 2150452. ISSN 2150-5594

Phothichaisri, W., Chankhamhaengdecha, S., Janvilisri, T. et al. (4 more authors) (2022) Potential role of the host-derived cell-wall binding domain of endolysin CD16/50L as a molecular anchor in preservation of uninfected clostridioides difficile for new rounds of phage infection. Microbiology Spectrum, 10 (2). e0236121. ISSN 2165-0497

Lanzoni-Mangutchi, P., Banerji, O., Wilson, J. orcid.org/0000-0002-6967-0809 et al. (12 more authors) (2022) Structure and assembly of the S-layer in C. difficile. Nature Communications, 13 (1). 970.

Jabbar Alabdali, Y.A., Oatley, P., Kirk, J.A. et al. (1 more author) (2021) A cortex-specific penicillin-binding protein contributes to heat resistance in Clostridioides difficile spores. Anaerobe, 70. 102379. ISSN 1075-9964

Fuchs, M., Lamm-Schmidt, V., Sulzer, J. et al. (7 more authors) (2021) An RNA-centric global view of Clostridioides difficile reveals broad activity of Hfq in a clinically important gram-positive bacterium. Proceedings of the National Academy of Sciences, 118 (25). e2103579118. ISSN 0027-8424

Oatley, P., Kirk, J.A., Ma, S. et al. (2 more authors) (2020) Spatial organization of Clostridium difficile S-layer biogenesis. Scientific Reports, 10 (1). 14089. ISSN 2045-2322

Janganan, T.K., Mullin, N., Dafis-Sagarmendi, A. et al. (8 more authors) (2020) Architecture and self-assembly of clostridium sporogenes and clostridium botulinum spore surfaces illustrate a general protective strategy across spore formers. mSphere, 5 (4). e00424-20.

Alabdali, Y.A.J., Oatley, P., Kirk, J.A. et al. (1 more author) (2019) A cortex-specific PBP contributes to cephalosporin resistance in Clostridium difficile. bioRxiv. (Submitted)

Kirk, J.A., Gebhart, D., Buckley, A.M. et al. (5 more authors) (2017) New Class of Precision Antimicrobials Redefines Role of Clostridium difficile S-layer in Virulence and Viability. Science Translational Medicine, 9 (406). eaah6813. ISSN 1946-6234

Kirk, J.A., Banerji, O. and Fagan, R.P. orcid.org/0000-0002-8704-4828 (2017) Characteristics of the Clostridium difficile cell envelope and its importance in therapeutics. Microbial Biotechnology, 10 (1). pp. 76-90. ISSN 1751-7915

Janganan, T.K., Mullin, N., Tzokov, S.B. et al. (5 more authors) (2016) Characterization of the spore surface and exosporium proteins of Clostridium sporogenes; implications for C. botulinum Group I strains. Food Microbiology, 59. pp. 205-212. ISSN 0740-0020

Buckley, A.M., Jukes, C., Candlish, D. et al. (7 more authors) (2016) Lighting Up Clostridium Difficile: Reporting Gene Expression Using Fluorescent Lov Domains. Scientific Reports, 6. 23463. ISSN 2045-2322

Willing, S.E., Candela, T., Shaw, H.A. et al. (4 more authors) (2015) Clostridium difficile surface proteins are anchored to the cell wall using CWB2 motifs that recognise the anionic polymer PSII. Molecular Microbiology, 96 (3). 596 - 608. ISSN 0950-382X

Dembek, M., Barquist, L., Boinett, C.J. et al. (5 more authors) (2015) High-Throughput Analysis of Gene Essentiality and Sporulation in Clostridium difficile. mBio, 6 (2). e02383-14. ISSN 2150-7511

Fagan, R.P. orcid.org/0000-0002-8704-4828 and Fairweather, N.F. (2014) Biogenesis and functions of bacterial S-layers. Nature Reviews Microbiology, 12. 3. pp. 211-222. ISSN 1740-1526

Pettit, L.J., Browne, H.P., Yu, L. et al. (10 more authors) (2014) Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism. BMC Genomics, 15. 160. ISSN 1471-2164

Mahon, V., Fagan, R.P. and Smith, S.G. (2012) Snap denaturation reveals dimerization by AraC-like protein Rns. Biochimie, 94 (9). 2058 - 2061.

Deakin, L.J., Clare, S., Fagan, R.P. et al. (7 more authors) (2012) The Clostridium difficile spo0A gene is a persistence and transmission factor. Infection and Immunity, 80 (8). 2704 - 2711.

Reynolds, C.B., Emerson, J.E., de la Riva, L. et al. (2 more authors) (2011) The Clostridium difficile cell wall protein CwpV is antigenically variable between strains, but exhibits conserved aggregation-promoting function. PLoS Pathogens, 7 (4). e1002024. .

Emerson, J.E., Reynolds, C.B., Fagan, R.P. et al. (3 more authors) (2009) A novel genetic switch controls phase variable expression of CwpV, a Clostridium difficile cell wall protein. Molecular Microbiology, 74 (3). 541 - 556.

Fagan, R.P., Lambert, M.A. and Smith, S.G. (2008) The hek outer membrane protein of Escherichia coli strain RS218 binds to proteoglycan and utilizes a single extracellular loop for adherence, invasion, and autoaggregation. Infection and Immunity, 76 (3). 1135 - 1142.

Preprint

Buddle, J.E. orcid.org/0000-0002-7259-0527, Wright, R.C.T. orcid.org/0000-0002-8095-8256, Turner, C.E. orcid.org/0000-0002-4458-9748 et al. (3 more authors) (2023) Multiple evolutionary pathways lead to vancomycin resistance in Clostridioides difficile. [Preprint] (Submitted)

Wilson, J.S. orcid.org/0000-0002-6967-0809, Fortier, L.-C. orcid.org/0000-0003-1950-763X, Fagan, R.P. orcid.org/0000-0002-8704-4828 et al. (1 more author) (2023) Molecular mechanism of bacteriophage tail contraction- structure of an S-layer-penetrating bacteriophage. [Preprint] (Submitted)

Ormsby, M.J., Vaz, F., Kirk, J.A. et al. (8 more authors) (2022) An intact S-layer is advantageous to Clostridioides difficile within the host. [Preprint] (Submitted)

Royer, A.L.M, Umansky, A.A., Allen, M.-M. et al. (7 more authors) (2022) The Clostridioides difficile S-Layer Protein A (SlpA) serves as a general phage receptor. [Preprint] (Submitted)