Items where authors include "Edwards, TA"

Article

Hopkins, FR, Álvarez-Rodríguez, B, Heath, GR orcid.org/0000-0001-6431-2191 et al. (5 more authors) (2022) The Native Orthobunyavirus Ribonucleoprotein Possesses a Helical Architecture. mBio. ISSN 2161-2129

Hóbor, F, Hegedüs, Z, Ibarra, AA et al. (5 more authors) (2022) Understanding p300-transcription factor interactions using sequence variation and hybridization. RSC Chemical Biology, 3 (5). pp. 592-603. ISSN 2633-0679

Mohamad, M, Nicholson, D, Saha, CK et al. (5 more authors) (2022) Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci. Nucleic Acids Research. ISSN 0305-1048

Hetherington, K, Dutt, S, Ibarra, AA et al. (7 more authors) (2021) Towards Optimizing Peptide-Based Inhibitors of Protein-Protein Interactions: Predictive Saturation Variation Scanning (PreSaVS). RSC Chemical Biology. ISSN 2633-0679

Haza, KZ, Martin, HL, Rao, A et al. (18 more authors) (2021) RAS-inhibiting biologics identify and probe druggable pockets including an SII-α3 allosteric site. Nature Communications, 12. 4045. ISSN 2041-1723

Celis, S orcid.org/0000-0001-8177-2472, Hobor, F, James, T et al. (11 more authors) (2021) Query-Guided Protein-Protein Interaction Inhibitor Discovery. Chemical Science, 12 (13). pp. 4753-4762. ISSN 2041-6520

Hegedüs, Z, Hóbor, F, Shoemark, DK et al. (6 more authors) (2021) Identification of β-strand mediated protein–protein interaction inhibitors using ligand-directed fragment ligation. Chemical Science. ISSN 2041-6520

Miles, JA orcid.org/0000-0001-8839-9201, Hobor, F, Trinh, C orcid.org/0000-0002-5087-5011 et al. (12 more authors) (2021) Selective Affimers Recognise the BCL‐2 Family Proteins BCL‐xL and MCL‐1 through Noncanonical Structural Motifs. ChemBioChem, 22 (1). pp. 232-240. ISSN 1439-4227

Nicholson, D orcid.org/0000-0001-5404-8251, Edwards, TA orcid.org/0000-0002-1467-3674, O'Neill, AJ orcid.org/0000-0003-3222-5493 et al. (1 more author) (2020) Structure of the 70S ribosome from the human pathogen Acinetobacter baumannii in complex with clinically-relevant antibiotics. Structure, 28 (10). pp. 1087-1100. ISSN 0969-2126

Hoste, ACR orcid.org/0000-0001-6724-6062, Ruiz, T, Fernández‐Pacheco, P et al. (8 more authors) (2020) Development of a multiplex assay for antibody detection in serum against pathogens affecting ruminants. Transboundary and Emerging Diseases. ISSN 1865-1674

Hetherington, K, Hegedus, Z, Edwards, TA orcid.org/0000-0002-1467-3674 et al. (3 more authors) (2020) Stapled Peptides as HIF‐1α/p300 Inhibitors: Helicity Enhancement in the Bound State Increases Inhibitory Potency. Chemistry: A European Journal, 26 (34). pp. 7638-7646. ISSN 0947-6539

Álvarez-Rodríguez, B, Tiede, C orcid.org/0000-0003-0280-4005, Hoste, ACR orcid.org/0000-0001-6724-6062 et al. (11 more authors) (2020) Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric diagnostic tests. PLOS Neglected Tropical Diseases, 14 (6). e0008364. ISSN 1935-2727

Ibarra, AA, Bartlett, GJ, Hegedüs, Z et al. (10 more authors) (2019) Predicting and Experimentally Validating Hot-spot Residues at Protein-Protein Interfaces. ACS Chemical Biology, 14 (10). pp. 2252-2263. ISSN 1554-8929

Davies, K, Afrough, B, Mankouri, J orcid.org/0000-0002-4325-3687 et al. (3 more authors) (2019) Tula orthohantavirus nucleocapsid protein is cleaved in infected cells and may sequester activated caspase-3 during persistent infection to suppress apoptosis. Journal of General Virology, 100 (8). pp. 1208-1221. ISSN 0022-1317

Fuller, J orcid.org/0000-0001-8801-149X, Surtees, RA, Shaw, AB et al. (7 more authors) (2019) Hazara nairovirus elicits differential induction of apoptosis and nucleocapsid protein cleavage in mammalian and tick cells. The Journal of General Virology, 100 (3). pp. 392-402. ISSN 0022-1317

Easton, V, McPhillie, M, Garcia-Dorival, I et al. (5 more authors) (2018) Identification of a small molecule inhibitor of Ebolavirus genome replication and transcription using in silico screening. Antiviral Research, 156. pp. 46-54. ISSN 0166-3542

Burslem, GM, Kyle, HF, Nelson, A et al. (2 more authors) (2018) Correction: Correction: Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions. Chemical Science, 9 (7). pp. 2010-2011. ISSN 2041-6520

Burslem, GM, Kyle, HF, Nelson, A et al. (2 more authors) (2018) Further Correction: Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions. Chemical Science, 9 (7). pp. 2008-2009. ISSN 2041-6520

Hughes, DJ, Tiede, C orcid.org/0000-0003-0280-4005, Penswick, N et al. (12 more authors) (2017) Generation of specific inhibitors of SUMO-1– and SUMO-2/3–mediated protein-protein interactions using Affimer (Adhiron) technology. Science Signaling, 10 (505). eaaj2005. ISSN 1945-0877

Burslem, GM, Kyle, HF, Nelson, A orcid.org/0000-0003-3886-363X et al. (2 more authors) (2017) Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions. Chemical Science, 8 (6). pp. 4188-4202. ISSN 2041-6520

Surtees, R, Dowall, SD, Shaw, A et al. (7 more authors) (2016) Heat Shock Protein 70 family members interact with Crimean-Congo hemorrhagic fever virus and Hazara virus nucleocapsid proteins and perform a functional role in the nairovirus replication cycle. Journal of Virology, 90 (20). pp. 9305-9316. ISSN 0022-538X

Haywood, NJ, Wolny, M, Rogers, B et al. (4 more authors) (2016) Hypertrophic cardiomyopathy mutations in the calponin-homology domain of ACTN2 affect actin binding and cardiomyocyte Z-disc incorporation. Biochemical Journal, 473 (16). pp. 2485-2493. ISSN 0264-6021

Miles, JA, Yeo, DJ, Rowell, P et al. (5 more authors) (2016) Hydrocarbon constrained peptides – understanding preorganisation and binding affinity. Chemical Science, 7 (6). pp. 3694-3702. ISSN 2041-6520

Stevenson, SR, Kamisugi, Y orcid.org/0000-0002-5265-3658, Trinh, CH et al. (15 more authors) (2016) Genetic analysis of Physcomitrella patens identifies ABSCISIC ACID NON-RESPONSIVE, a regulator of ABA responses unique to basal land plants and required for desiccation tolerance. Plant Cell, 28 (6). pp. 1310-1327. ISSN 1040-4651

Burslem, G, Kyle, H, Breeze, AL orcid.org/0000-0001-9723-3350 et al. (4 more authors) (2016) Towards “Bionic” Proteins: Replacement of Continuous Sequences from HIF-1α with Proteomimetics to Create Functional p300 Binding HIF-1α Mimics. Chemical Communications, 52 (31). pp. 5421-5424. ISSN 1359-7345

Azzarito, V, Rowell, P, Barnard, A et al. (4 more authors) (2016) Probing Protein Surfaces: QSAR Analysis using Helix Mimetics. ChemBioChem, 17 (8). pp. 768-773. ISSN 1439-4227

Burslem, GM, Kyle, HF, Prabhakaran, P et al. (5 more authors) (2016) Synthesis of Highly Functionalized Oligobenzamide Proteomimetic Foldamers by Late Stage Introduction of Sensitive Groups. Organic and Biomolecular Chemistry, 2016 (14). pp. 3782-3786. ISSN 1477-0520

Sharkey, LKR, Edwards, TA and O'Neill, AJ (2016) ABC-F proteins mediate antibiotic resistance through ribosomal protection. mBio, 7 (2). e01975-15.

Surtees, R, Ariza, A, Punch, EK et al. (6 more authors) (2015) The crystal structure of the Hazara virus nucleocapsid protein. BMC Structural Biology, 15 (24). ARTN 24. ISSN 1472-6807

Kyle, HF, Wickson, KF, Stott, J et al. (8 more authors) (2015) Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies. Molecular Biosystems, 11 (10). 2738 - 2749. ISSN 1742-206X

Barnard, A, Long, K, Martin, HL et al. (5 more authors) (2015) Selective and Potent Proteomimetic Inhibitors of Intracellular Protein-Protein Interactions. Angewandte Chemie, 127 (10). pp. 3003-3008. ISSN 0044-8249

Barnard, A, Long, K, Martin, HL et al. (5 more authors) (2015) Selective and potent proteomimetic inhibitors of intracellular protein-protein interactions. Angewandte Chemie - International Edition, 54 (10). pp. 2960-2965. ISSN 1433-7851

Azzarito, V, Miles, JA orcid.org/0000-0001-8839-9201, Fisher, J et al. (3 more authors) (2015) Stereocontrolled protein surface recognition using chiral oligoamide proteomimetic foldamers. Chemical Science, 6 (4). pp. 2434-2443. ISSN 2041-6520

Barnard, A, Long, K, Yeo, DJ et al. (6 more authors) (2014) Orthogonal functionalisation of α-helix mimetics. Organic and Biomolecular Chemistry, 12 (35). 6794 - 6799. ISSN 1477-0520

Burslem, GM, Kyle, HF, Breeze, AL et al. (4 more authors) (2014) Small-molecule proteomimetic inhibitors of the HIF-1α-p300 protein-protein interaction. ChemBioChem, 15 (8). 1083 - 1087. ISSN 1439-4227

Shepherd, DA, Ariza, A, Edwards, TA et al. (3 more authors) (2014) Probing Bunyavirus N protein oligomerisation using mass spectrometry. Rapid Communications in Mass Spectrometry, 28 (7). 793 - 800. ISSN 0951-4198

Tanner, S, Ariza, A, Richard, CA et al. (12 more authors) (2014) Crystal structure of the essential transcription antiterminator M2-1 protein of human respiratory syncytial virus and implications of its phosphorylation. Proceedings of the National Academy of Sciences, 111 (4). pp. 1580-1585. ISSN 0027-8424

Cox, G, Edwards, TA and O'Neill, AJ (2013) Mutagenesis mapping of the protein-protein interaction underlying FusB-type Fusidic acid resistance. Antimicrobial Agents and Chemotherapy, 57 (10). 4640 - 4644. ISSN 0066-4804

Ariza, A, Tanner, SJ, Walter, CT et al. (14 more authors) (2013) Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization. Nucleic Acids Research, 41 (11). 5912 - 5926 (15). ISSN 0305-1048

Fuller, J, Jackson, R, Edwards, TA et al. (2 more authors) (2012) Modeling of arylamide helix mimetics in the p53 peptide binding site of hDM2 suggests parallel and anti-parallel conformations are both stable. PLoS One, 7 (8). e43253. ISSN 1932-6203

Book Section

Muniyandi, S, Pangratiou, G, Edwards, TA orcid.org/0000-0002-1467-3674 et al. (1 more author) (2018) Structure and Function of the Human Respiratory Syncytial Virus M2–1 Protein. In: Harris, JR and Bhella, D, (eds.) Virus Protein and Nucleoprotein Complexes. Subcellular Biochemistry, 88 . Springer Singapore , Singapore , pp. 245-260.