Items where authors include "De Vos, K.J."

Article

Castelli, L.M., Lin, Y.-H., Sanchez-Martinez, A. et al. (19 more authors) (2023) A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. Science Translational Medicine, 15 (685). ISSN 1946-6234

Bauer, C.S., Webster, C.P., Shaw, A.C. et al. (12 more authors) (2022) Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation. Frontiers in Cellular Neuroscience, 16. 1061559. ISSN 1662-5102

Marchi, P.M. orcid.org/0000-0002-8893-3790, Marrone, L., Brasseur, L. et al. (19 more authors) (2022) C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons. Life Science Alliance, 5 (9). e202101276. ISSN 2575-1077

Bauer, C.S., Cohen, R.N., Sironi, F. et al. (11 more authors) (2022) An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD. Acta Neuropathologica, 144 (3). pp. 437-464. ISSN 0001-6322

Smith, E.F., Shaw, P.J. and De Vos, K.J. orcid.org/0000-0003-2161-6309 (2019) The Role of Mitochondria in Amyotrophic Lateral Sclerosis. Neuroscience Letters, 710. 132933. ISSN 0304-3940

Moller, A., Bauer, C.S., Cohen, R.N. et al. (2 more authors) (2017) Amyotrophic lateral sclerosis-associated mutant SOD1 inhibits anterograde axonal transport of mitochondria by reducing Miro1 levels. Human Molecular Genetics, 26 (23). pp. 4668-4679. ISSN 0964-6906

Walker, C., Herranz-Martin, S., Karyka, E. et al. (19 more authors) (2017) C9orf72 Expansion Disrupts ATM-mediated Chromosomal Break Repair. Nature Neuroscience, 20 (9). pp. 1225-1235. ISSN 1097-6256

De Vos, K.J. orcid.org/0000-0003-2161-6309 and Hafezparast, M. (2017) Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research? Neurobiology of Disease, 105. pp. 283-299. ISSN 0969-9961

Hautbergue, G.M. orcid.org/0000-0002-1621-261X, Castelli, L.M., Ferraiuolo, L. et al. (23 more authors) (2017) SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits. Nature Communications, 8. 16063 (2017).

Stopford, M.J., Higginbottom, A., Hautbergue, G.M. et al. (14 more authors) (2017) C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten. Human Molecular Genetics, 26 (6). pp. 1133-1145. ISSN 0964-6906

Webster, C.P., Smith, E.F., Bauer, C.S. et al. (12 more authors) (2016) The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy. EMBO Journal, 35 (15). pp. 1656-1676.

Stoica, R., Paillusson, S., Gomez‐Suaga, P. et al. (10 more authors) (2016) ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP51 interaction and ER–mitochondria associations. EMBO Reports. e201541726. ISSN 1469-3178

Rodríguez-Martín, T., Pooler, A.M., Lau, D.H. et al. (5 more authors) (2016) Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons. Neurobiology of Disease, 85. pp. 1-10. ISSN 0969-9961

Godena, V.K., Brookes-Hocking, N., Moller, A. et al. (6 more authors) (2014) Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations. Nature Communications, 5. 5245 . ISSN 2041-1723

Stoica, R., De Vos, K.J., Paillusson, S. et al. (12 more authors) (2014) ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43. Nature Communications, 5. 3996 .

Mórotz, G.M., De Vos, K.J., Vagnoni, A. et al. (3 more authors) (2012) Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria. Human Molecular Genetics, 21 (9). 1979 - 1988. ISSN 0964-6906

De Vos, K.J., Morotz, G.M., Stoica, R. et al. (6 more authors) (2011) VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis. Human Molecular Genetics, 21 (6). 1299 - 1311. ISSN 0964-6906

Manser, C., Guillot, F., Vagnoni, A. et al. (5 more authors) (2011) Lemur tyrosine kinase-2 signalling regulates kinesin-1 light chain-2 phosphorylation and binding of Smad2 cargo. Oncogene, 31 (22). 2773 - 2782. ISSN 0950-9232

Sargsyan, S.A., Blackburn, D.J., Barber, S.C. et al. (4 more authors) (2011) A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function. BMC Neuroscience, 12. 91. ISSN 1471-2202

von Wichert, G., Jiang, G., Kostic, A. et al. (3 more authors) (2003) RPTP-alpha acts as a transducer of mechanical force on alphav/beta3-integrin-cytoskeleton linkages. The Journal of Cell Biology (JCB), 161 (1). 143 - 153. ISSN 0021-9525