Items where authors include "Coldicott, I."

Article

Webster, C.P. orcid.org/0000-0003-4197-2036, Hall, B. orcid.org/0009-0008-4274-9796, Crossley, O.M. et al. (14 more authors) (2025) RuvBL1/2 reduce toxic dipeptide repeat protein burden in multiple models of C9orf72-ALS/FTD. Life Science Alliance, 8 (2). e202402757. ISSN 2575-1077

Badger, S.E. orcid.org/0009-0009-3696-8578, Coldicott, I., Kyrgiou-Balli, E. et al. (7 more authors) (2025) A bacterial artificial chromosome mouse model of amyotrophic lateral sclerosis manifests ‘space cadet syndrome’ on two FVB backgrounds. Disease Models & Mechanisms, 18 (2). ISSN 1754-8403

Wiseman, J.P., Scarrott, J.M. orcid.org/0000-0002-6046-7687, Alves-Cruzeiro, J. et al. (21 more authors) (2024) Pre-clinical development of AP4B1 gene replacement therapy for hereditary spastic paraplegia type 47. EMBO Molecular Medicine, 16 (11). pp. 2882-2917. ISSN 1757-4676

Scarrott, J.M. orcid.org/0000-0002-6046-7687, Alves-Cruzeiro, J., Marchi, P.M. et al. (7 more authors) (2023) Ap4b1-knockout mouse model of hereditary spastic paraplegia type 47 displays motor dysfunction, aberrant brain morphology and ATG9A mislocalization. Brain Communications, 5 (1). fcac335.

Alix, J.J.P. orcid.org/0000-0001-8391-9749, Plesia, M., Hool, S.A. et al. (5 more authors) (2022) Fiber optic Raman spectroscopy for the evaluation of disease state in Duchenne muscular dystrophy: An assessment using the mdx model and human muscle. Muscle and Nerve, 66 (3). pp. 362-369. ISSN 0148-639X

Bauer, C.S., Cohen, R.N., Sironi, F. et al. (11 more authors) (2022) An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD. Acta Neuropathologica, 144 (3). pp. 437-464. ISSN 0001-6322

Marrone, L., Marchi, P.M. orcid.org/0000-0002-8893-3790, Webster, C.P. orcid.org/0000-0003-4197-2036 et al. (11 more authors) (2022) SPG15 protein deficits are at the crossroads between lysosomal abnormalities, altered lipid metabolism and synaptic dysfunction. Human Molecular Genetics, 31 (16). pp. 2693-2710. ISSN 0964-6906

Plesia, M., Stevens, O.A., Lloyd, G.R. et al. (8 more authors) (2021) In vivo fiber optic raman spectroscopy of muscle in preclinical models of amyotrophic lateral sclerosis and Duchenne muscular dystrophy. ACS Chemical Neuroscience, 12 (10). pp. 1768-1776. ISSN 1948-7193

Allen, S.P., Hall, B., Woof, R. et al. (16 more authors) (2019) C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis. Brain. 302. pp. 1-20. ISSN 0006-8950

Alrafiah, A., Karyka, E., Coldicott, I. et al. (4 more authors) (2018) Plastin 3 Promotes Motor Neuron Axonal Growth and Extends Survival in a Mouse Model of Spinal Muscular Atrophy. Molecular Therapy - Methods and Clinical Development, 9. pp. 81-89. ISSN 2329-0501

Chandran, J.S., Sharp, P.S., Karyka, E. et al. (6 more authors) (2017) Site specific modification of adeno-associated virus enables both fluorescent imaging of viral particles and characterization of the capsid interactome. Scientific Reports, 7. 14766. ISSN 2045-2322

Walker, C., Herranz-Martin, S., Karyka, E. et al. (19 more authors) (2017) C9orf72 Expansion Disrupts ATM-mediated Chromosomal Break Repair. Nature Neuroscience, 20 (9). pp. 1225-1235. ISSN 1097-6256

Herranz-Martin, S., Chandran, J. orcid.org/0000-0002-3486-8583, Lewis, K. et al. (12 more authors) (2017) Viral delivery of C9ORF72 hexanucleotide repeat expansions in mice lead to repeat length dependent neuropathology and behavioral deficits. Disease Models and Mechanisms. ISSN 1754-8403

Lukashchuk, V., Lewis, K.E., Coldicott, I. et al. (2 more authors) (2016) AAV9-mediated central nervous system-targeted gene delivery via cisterna magna route in mice. Molecular Therapy - Methods and Clinical Development, 3. 15055. ISSN 2329-0501