Items where authors include "Brenner, H."

Article

Yiangou, K., Mavaddat, N., Dennis, J. et al. (124 more authors) (2024) Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction. Breast Cancer Research, 26. 189. ISSN 1465-5411

Feigin, V.L., Abate, M.D., Abate, Y.H. et al. (1400 more authors) (2024) Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet Neurology, 23 (10). pp. 973-1003. ISSN 1474-4422

Kentistou, K.A. orcid.org/0000-0002-5816-664X, Kaisinger, L.R. orcid.org/0000-0002-0849-3191, Stankovic, S. orcid.org/0000-0002-6602-1379 et al. (220 more authors) (2024) Understanding the genetic complexity of puberty timing across the allele frequency spectrum. Nature Genetics, 56 (7). pp. 1397-1411. ISSN 1061-4036

Hilgers, L., Ghaffari Laleh, N., West, N.P. orcid.org/0000-0002-0346-6709 et al. (13 more authors) (2024) Automated curation of large‐scale cancer histopathology image datasets using deep learning. Histopathology, 84 (7). pp. 1139-1153. ISSN 0309-0167

Gustav, M. orcid.org/0009-0009-3598-5720, Reitsam, N.G. orcid.org/0000-0002-0070-3158, Carrero, Z.I. orcid.org/0000-0001-8501-1566 et al. (15 more authors) (2024) Deep learning for dual detection of microsatellite instability and POLE mutations in colorectal cancer histopathology. npj Precision Oncology, 8. 115. ISSN 2397-768X

Schumacher, A.E., Kyu, H.H., Aali, A. et al. (1833 more authors) (2024) Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021. The Lancet, 403 (10440). pp. 1989-2056. ISSN 0140-6736

Ferrari, A.J., Santomauro, D.F., Aali, A. et al. (1325 more authors) (2024) Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet, 403 (10440). pp. 2133-2161. ISSN 0140-6736

Vollset, S.E., Ababneh, H.S., Abate, Y.H. et al. (1417 more authors) (2024) Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021. The Lancet, 403 (10440). pp. 2204-2256. ISSN 0140-6736

Brauer, M., Roth, G.A., Aravkin, A.Y. et al. (1792 more authors) (2024) Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet, 403 (10440). pp. 2162-2203. ISSN 0140-6736

Naghavi, M., Ong, K.L., Aali, A. et al. (1997 more authors) (2024) Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet, 403 (10440). pp. 2100-2132. ISSN 0140-6736

Steinmetz, J.D., Seeher, K.M., Schiess, N. et al. (1261 more authors) (2024) Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet Neurology, 23 (4). pp. 344-381. ISSN 1474-4422

Truhn, D., Arasteh, S.T., Saldanha, O.L. et al. (24 more authors) (2024) Encrypted federated learning for secure decentralized collaboration in cancer image analysis. Medical Image Analysis, 92. 103059. ISSN 1361-8415

Watts, E.L. orcid.org/0000-0001-9229-2589, Gonzales, T.I. orcid.org/0000-0003-0085-8771, Strain, T. et al. (91 more authors) (2024) Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study. British Journal of Cancer, 130 (1). pp. 114-124. ISSN 0007-0920

West, N. orcid.org/0000-0002-0346-6709, Jiang, X., Hoffmeister, M. et al. (16 more authors) (2024) End-to-end prognostication in colorectal cancer by Deep Learning: a multicentric retrospective study. The Lancet: Digital Health, 6 (1). E33-E43. ISSN 2589-7500

Levi, H., Carmi, S., Rosset, S. et al. (135 more authors) (2023) Evaluation of European-based polygenic risk score for breast cancer in Ashkenazi Jewish women in Israel. Journal of Medical Genetics, 60 (12). ISSN 0022-2593

Perna, L., Stocker, H., Burow, L. et al. (12 more authors) (2023) Subjective cognitive complaints and blood biomarkers of neurodegenerative diseases: a longitudinal cohort study. Alzheimer's Research & Therapy, 15 (1). 198. ISSN 1758-9193

Wichert, K. orcid.org/0000-0001-7708-7843, Hoppe, R., Ickstadt, K. et al. (45 more authors) (2023) Polymorphisms in genes of melatonin biosynthesis and signaling support the light-at-night hypothesis for breast cancer. European Journal of Epidemiology, 38. pp. 1053-1068. ISSN 0393-2990

Thomas, M. orcid.org/0000-0001-9337-7015, Su, Y.-R., Rosenthal, E.A. orcid.org/0000-0001-6042-4487 et al. (126 more authors) (2023) Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations. Nature Communications, 14. 6147. ISSN 2041-1723

Wagner, S.J., Reisenbüchler, D., West, N.P. et al. (46 more authors) (2023) Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study. Cancer Cell, 41. ISSN 1535-6108

Fares, A.F., Li, Y., Jiang, M. et al. (52 more authors) (2023) Association between duration of smoking abstinence before non-small-cell lung cancer diagnosis and survival: a retrospective, pooled analysis of cohort studies. The Lancet Public Health, 8 (9). e691-e700. ISSN 2468-2667

Middha, P., Wang, X., Behrens, S. et al. (129 more authors) (2023) A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry. Breast Cancer Research, 25. 93.

Perna, L., Mons, U., Stocker, H. et al. (8 more authors) (2023) High cholesterol levels change the association of biomarkers of neurodegenerative diseases with dementia risk: findings from a population‐based cohort. Alzheimer's & Dementia, 19 (7). pp. 2913-2922. ISSN 1552-5260

Dixon-Suen, S.C. orcid.org/0000-0003-3714-8386, Lewis, S.J., Martin, R.M. et al. (155 more authors) (2022) Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study. British Journal of Sports Medicine, 56 (20). pp. 1157-1170. ISSN 0306-3674

Tran, K.B., Lang, J.J., Compton, K. et al. (1020 more authors) (2022) The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet, 400 (10352). pp. 563-591. ISSN 0140-6736

Escala-Garcia, M., Guo, Q., Dörk, T. et al. (234 more authors) (2019) Genome-wide association study of germline variants and breast cancer-specific mortality. British Journal of Cancer, 120. pp. 647-657. ISSN 0007-0920

O'Mara, T.A. orcid.org/0000-0002-5436-3232, Glubb, D.M. orcid.org/0000-0002-2184-7708, Amant, F. et al. (122 more authors) (2018) Identification of nine new susceptibility loci for endometrial cancer. Nature Communications, 9 (1). 3166. ISSN 2041-1723

Painter, J.N., O'Mara, T.A., Morris, A.P. et al. (73 more authors) (2018) Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses. Cancer Medicine, 7 (5). pp. 1978-1987. ISSN 2045-7634

Colombo, M., Lopez-Perolio, I., Meeks, H.D. et al. (112 more authors) (2018) The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity. Human Mutation, 39 (5). pp. 729-741. ISSN 1059-7794

Rudolf, A., Song, M., Brook, M.N. et al. (48 more authors) (2018) Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium. International Journal of Epidemiology, 47 (2). pp. 526-536. ISSN 0300-5771

Guo, Q., Burgess, S., Turman, C. et al. (132 more authors) (2017) Body mass index and breast cancer survival: a Mendelian randomization analysis. International Journal of Epidemiology, 46 (6). pp. 1814-1822. ISSN 0300-5771

Barrdahl, M. orcid.org/0000-0003-4661-0763, Rudolph, A. orcid.org/0000-0001-7520-2035, Hopper, J.L. et al. (45 more authors) (2017) Gene-environment interactions involving functional variants: results from the Breast Cancer Association Consortium. International Journal of Cancer, 141 (9). pp. 1830-1840. ISSN 0020-7136

Jiao, X., Aravidis, C., Marikkannu, R. et al. (103 more authors) (2017) PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1. Oncotarget, 8. pp. 102769-102782. ISSN 1949-2553

Shimelis, H., Mesman, R.L.S., Von Nicolai, C. et al. (130 more authors) (2017) BRCA2 hypomorphic missense variants confer moderate risks of breast cancer. Cancer Research, 77 (11). pp. 2789-2799. ISSN 0008-5472

Day, F.R., Thompson, D.J., Helgason, H. et al. (219 more authors) (2017) Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nature Genetics, 49 (6). pp. 834-841. ISSN 1061-4036

Ghoussaini, M, French, J.D., Michailidou, K. et al. (122 more authors) (2016) Evidence that the 5p12 variant rs10941679 confers susceptibility to estrogen receptor positive breast cancer through FGF10 and MRPS30 regulation. American Journal of Human Genetics, 99 (4). pp. 903-911. ISSN 0002-9297

Shi, J., Zhang, Y., Zheng, W. et al. (125 more authors) (2016) Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer. International Journal of Cancer, 139 (6). pp. 1303-1317. ISSN 0020-7136

Darabi, H., Beesley, J., Droit, A. et al. (111 more authors) (2016) Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs). Scientific Reports, 6. p. 32512. ISSN 2045-2322

Horne, H.N., Chung, C.E., Zhang, H. et al. (112 more authors) (2016) Fine-mapping of the 1p11.2 breast cancer susceptibility locus. PLoS One, 11 (8). e0160316. ISSN 1932-6203

Guo, Y., Warren Andersen, S., Shu, X.O. et al. (108 more authors) (2016) Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent. PLoS Medicine, 13 (8). e1002105. ISSN 1549-1277

Chen, L.S., Baker, T., Hung, R.J. et al. (47 more authors) (2016) Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-analysis. EBioMedicine.

Wyszynski, A., Hong, C.C., Lam, K. et al. (107 more authors) (2016) An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression. Human Molecular Genetics , 25 (17). pp. 3863-3876. ISSN 0964-6906

Zeng, C., Guo, X., Long, J. et al. (234 more authors) (2016) Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. Breast Cancer Research, 18 (1). 64. ISSN 1465-542X

Schmidt, M.J., Cox, A. orcid.org/0000-0002-5138-1099, Hogervorst, F. et al. (81 more authors) (2016) Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers. Journal of Clinical Oncology, 34 (23). pp. 2750-2760. ISSN 0732-183X

Hollestelle, A., van der Baan, F.H., Berchuck, A. et al. (355 more authors) (2016) No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer. Gynecologic Oncology, 141 (2). pp. 386-401. ISSN 0090-8258

Zhao, Z., Wen, W., Michailidou, K. et al. (115 more authors) (2016) Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry. Cancer Causes and Control. pp. 1-15. ISSN 0957-5243

Dunning, A.M., Michailidou, K., Kuchenbaecker, K.B. et al. (245 more authors) (2016) Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170. Nature Genetics. ISSN 1061-4036

Easton, D.F., Lesueur, F., Decker, B. et al. (126 more authors) (2016) No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing. Journal of Medical Genetics . ISSN 0022-2593

Petridis, C., Brook, M.N., Shah, V. et al. (92 more authors) (2016) Genetic predisposition to ductal carcinoma in situ of the breast. Breast Cancer Research, 18 (1). 22. ISSN 1465-542X

Lei, J., Rudolph, A., Moysich, K.B. et al. (67 more authors) (2016) Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium. Human Genetics, 135 (1). pp. 137-154. ISSN 0340-6717

Hamdi, Y., Soucy, P., Adoue, V. et al. (93 more authors) (2016) Association of Breast Cancer Risk with Genetic Variants Showing Differential Allelic Expression: Identification of a Novel Breast Cancer Susceptibility Locus at 4q21. Oncotarget, 7. pp. 80140-80163. ISSN 1949-2553

Cheng, T.H.T., Thompson, D., Painter, J. et al. (98 more authors) (2015) Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1. Scientific Reports, 5. 17369. ISSN 2045-2322

Huang, R., Wei, Y., Hung, R.J. et al. (53 more authors) (2015) Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium. EBioMedicine, 2 (11). pp. 1677-1685. ISSN 2352-3964

Guo, X., Long, J., Zeng, C. et al. (112 more authors) (2015) Fine-Scale Mapping of the 4q24 Locus Identifies Two Independent Loci Associated with Breast Cancer Risk. Cancer Epidemiology, Biomarkers and Prevention, 24 (11). pp. 1680-1691. ISSN 1055-9965

Jamshidi, M., Fagerholm, R., Khan, S. et al. (55 more authors) (2015) SNP-SNP interaction analysis of NF-κB signaling pathway on breast cancer survival. Oncotarget, 6 (35). pp. 37979-37994. ISSN 1949-2553

Al Olama, A.A., Benlloch, S., Antoniou, A.C. et al. (65 more authors) (2015) Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci. Cancer Epidemiology, Biomarkers and Prevention, 24 (7). pp. 1121-1129. ISSN 1055-9965

Orr, N., Dudbridge, F., Dryden, N. et al. (213 more authors) (2015) Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2. Human Molecular Genetics, 24 (10). 2966 - 2984. ISSN 0964-6906

Candido dos Reis, F.J., Lynn, S., Ali, H.R. et al. (43 more authors) (2015) Crowdsourcing the general public for large scale molecular pathology studies in cancer. EBioMedicine, 2 (7). pp. 681-689. ISSN 2352-3964

Chen, L-S., Hung, R.J., Baker, T. et al. (53 more authors) (2015) CHRNA5 Risk Variant Predicts Delayed Smoking Cessation and Earlier Lung Cancer Diagnosis-A Meta-Analysis. JNCI: Journal of the National Cancer Institute , 107 (5). djv100. ISSN 0027-8874

Guo, Q., Schmidt, M.K., Kraft, P. et al. (143 more authors) (2015) Identification of Novel Genetic Markers of Breast Cancer Survival. Journal of the National Cancer Institute, 107 (5). ISSN 0027-8874

Mavaddat, N., Pharoah, P.D.P., Michailidou, K. et al. (209 more authors) (2015) Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants. JNCI-Journal of the National Cancer Institute, 107 (5). ISSN 0027-8874

Pirie, A., Guo, Q., Kraft, P. et al. (146 more authors) (2015) Common germline polymorphisms associated with breast cancer-specific survival. Breast Cancer Research, 17. 58. ISSN 1465-5411

Michailidou, K., Beesley, J., Lindstrom, S. et al. (245 more authors) (2015) Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. Nature Genetics, 47. pp. 373-380. ISSN 1061-4036

Painter, J.N., O'Mara, T.A., Batra, J. et al. (116 more authors) (2015) Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk. Human Molecular Genetics, 24 (5). pp. 1478-1492. ISSN 0964-6906

Carvajal-Carmona, L.G., O'Mara, T.A., Painter, J.N.. et al. (91 more authors) (2015) Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk. Human Genetics, 134 (2). pp. 231-245. ISSN 0340-6717

Spurdle, A.B., Couch, F.J., Parsons, M.T. et al. (195 more authors) (2014) Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia. Breast Cancer Research, 16. 3419. ISSN 1465-5411

Milne, R.L., Burwinkel, B., Michailidou, K. et al. (178 more authors) (2014) Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium. Human Molecular Genetics, 23 (22). pp. 6096-6111. ISSN 0964-6906

Khan, S., Greco, D., Michailidou, K. et al. (161 more authors) (2014) MicroRNA Related Polymorphisms and Breast Cancer Risk. PLOS ONE, 9 (11). e109973. ISSN 1932-6203

Johnson, N., Dudbridge, F., Orr, N. et al. (182 more authors) (2014) Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study. Breast Cancer Research , 16 (3). R51. ISSN 1465-5411

Sawyer, E., Roylance, R., Petridis, C. et al. (151 more authors) (2014) Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast. PLoS Genetics, 10 (4). e1004285. ISSN 1553-7390

Agarwal, D., Pineda, S., Michailidou, K. et al. (179 more authors) (2014) FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium. British Journal of Cancer, 110 (4). pp. 1088-1100. ISSN 0007-0920

Nickels, S., Truong, T., Hein, R. et al. (93 more authors) (2013) Evidence of Gene-Environment Interactions between Common Breast Cancer Susceptibility Loci and Established Environmental Risk Factors. PLoS Genetics, 9 (3). e1003284. ISSN 1553-7404

Gaudet, M.M., Kuchenbaecker, K.B., Vijai, J. et al. (129 more authors) (2013) Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk. PLoS Genetics, 9 (3). e1003173. ISSN 1553-7390

Cote, M.L., Liu, M., Bonassi, S. et al. (56 more authors) (2012) Increased risk of lung cancer in individuals with a family history of the disease: A pooled analysis from the International Lung Cancer Consortium. European Journal of Cancer, 48 (13). pp. 1957-1968. ISSN 0959-8049

Hein, R., Maranian, M., Hopper, J.L. et al. (168 more authors) (2012) Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC). PLoS ONE, 7 (8). e42380. ISSN 1932-6203

Brenner, H. and Katzman, M. (2004) On the arithmetic of tight closure. Journal of the American Mathematical Society, 19 (3). pp. 659-672. ISSN 0894-0347