Items where authors include "Almlöf, I."

Article

Luttens, A. orcid.org/0000-0003-2915-7901, Vo, D.D., Scaletti, E.R. et al. (22 more authors) (2025) Virtual fragment screening for DNA repair inhibitors in vast chemical space. Nature Communications, 16. 1741. ISSN 2041-1723

Valerie, N.C.K. orcid.org/0000-0002-9423-964X, Sanjiv, K., Mortusewicz, O. orcid.org/0000-0002-4290-4994 et al. (21 more authors) (2024) Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM. Nature Communications, 15. 10347. ISSN 2041-1723

Scaletti, E.R., Unterlass, J.E., Almlöf, I. et al. (7 more authors) (2024) Kinetic and structural characterization of NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis. The FEBS Journal, 291 (19). pp. 4301-4322. ISSN 1742-464X

Zhang, S.M., Paulin, C.B.J., Shu, H. et al. (24 more authors) (2024) Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel. iScience, 27 (2). 108907. ISSN 2589-0042

Sanjiv, K., Calderón-Montaño, J.M., Pham, T.M. et al. (29 more authors) (2021) MTH1 inhibitor TH1579 induces oxidative DNA damage and mitotic arrest in acute myeloid leukemia. Cancer Research, 81 (22). pp. 5733-5744. ISSN 0008-5472

Visnes, T., Benítez-Buelga, C., Cázares-Körner, A. et al. (43 more authors) (2020) Targeting OGG1 arrests cancer cell proliferation by inducing replication stress. Nucleic Acids Research, 48 (21). pp. 12234-12251. ISSN 0305-1048

Zhang, S.M., Desroses, M., Hagenkort, A. et al. (34 more authors) (2020) Development of a chemical probe against NUDT15. Nature Chemical Biology, 16 (10). pp. 1120-1128. ISSN 1552-4450

Das, I., Gad, H., Bräutigam, L. et al. (9 more authors) (2020) AXL and CAV-1 play a role for MTH1 inhibitor TH1579 sensitivity in cutaneous malignant melanoma. Cell Death & Differentiation, 27. pp. 2081-2098. ISSN 1350-9047

Michel, M., Homan, E.J., Wiita, E. et al. (6 more authors) (2020) In silico druggability assessment of the NUDIX hydrolase protein family as a workflow for target prioritization. Frontiers in Chemistry, 8. 443.

Jemth, A-S., Gustafsson, R., Bräutigam, L. et al. (9 more authors) (2018) MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP. Nucleic Acids Research, 46 (20). pp. 10888-10904. ISSN 0305-1048

Page, B.D.G., Valerie, N.C.K., Wright, R.H.G. et al. (22 more authors) (2018) Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. Nature Communications, 9 (1). 250. ISSN 2041-1723

Hagenkort, A., Paulin, C.B.J., Desroses, M. et al. (12 more authors) (2017) dUTPase inhibition augments replication defects of 5-Fluorouracil. Oncotarget, 8 (14). pp. 23713-23726.

Proceedings Paper

Walter, M. orcid.org/0000-0003-3241-522X, Homan, E., Koolmeister, T. et al. (3 more authors) (2021) Development of small molecule NUDT22 inhibitors for uses in cancer. In: Medical Sciences Forum. IECC 2021: 1st International Electronic Conference on Cancers, 01-14 Feb 2021, Online. MDPI .