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Number of items at this level: 53.


Adamson, H, Ajayi, MO, Campbell, E et al. (10 more authors) (2019) Affimer–Enzyme–Inhibitor Switch Sensor for Rapid Wash-free Assays of Multimeric Proteins. ACS Sensors, 4 (11). pp. 3014-3022. ISSN 2379-3694

Adamson, H, Nicholl, A, Tiede, C et al. (9 more authors) (2019) Affimers as anti-idiotypic affinity reagents for pharmacokinetic analysis of biotherapeutics. BioTechniques, 67 (6). ISSN 0736-6205


Balforth, MR, Haigh, J, Kumar, V et al. (6 more authors) (2021) Piggybacking on the Cholera Toxin: Identification of a CTB-binding Protein as an Approach for Targeted Delivery of Proteins to Motor Neurons. Bioconjugate Chemistry, 32 (10). pp. 2205-2212. ISSN 1043-1802

Bawazar, LA, McNally, CS, Empson, CJ et al. (8 more authors) (2016) Combinatorial microfluidic droplet engineering for biomimetic material synthesis. Science Advances, 2 (10). e1600567. ISSN 2375-2548

Bedford, R, Tiede, C, Hughes, R et al. (4 more authors) (2017) Alternative reagents to antibodies in imaging applications. In: Biophysical Reviews. 19th IUPAB Congress, 16-20 Jul 2017, Edinburgh, UK. Springer , pp. 299-308.

Bonetta, R, Hunter, GJ, Trinh, CH et al. (6 more authors) (2021) Substitution of histidine 30 by asparagine in manganese superoxide dismutase alters biophysical properties and supports proliferation in a K562 leukemia cell line. European Biophysics Journal, 50 (3-4). pp. 571-585. ISSN 0175-7571


Campbell, E., Adamson, H., Luxton, T. et al. (4 more authors) (2023) Therapeutic drug monitoring of immunotherapies with novel Affimer–NanoBiT sensor construct. Sensors & Diagnostics.

Curd, AP, Leng, J, Hughes, RE et al. (13 more authors) (2021) Nanoscale pattern extraction from relative positions of sparse 3D localizations. Nano Letters: a journal dedicated to nanoscience and nanotechnology, 21 (3). pp. 1213-1220. ISSN 1530-6984


Daniels, AD, Campeotto, I, van der Kamp, MW et al. (7 more authors) (2014) Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, QM/MM Simulation, and Mutagenesis. ACS Chemical Biology, 9 (4). pp. 1025-1032. ISSN 1554-8929

Drulyte, I, Obajdin, J, Trinh, CH et al. (4 more authors) (2019) Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase. IUCrJ, 6 (6). pp. 1120-1133. ISSN 2052-2525


Gaule, TG, Smith, MA, Tych, KM et al. (5 more authors) (2018) Oxygen Activation Switch in the Copper Amine Oxidase of Escherichia coli. Biochemistry, 57 (36). pp. 5301-5314. ISSN 0006-2960

Guthertz, N, van der Kant, R, Martinez, RM et al. (7 more authors) (2022) The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proceedings of the National Academy of Sciences (PNAS), 119 (22). e2200468119. ISSN 0027-8424


Hegedüs, Z, Hóbor, F, Shoemark, DK et al. (6 more authors) (2021) Identification of β-strand mediated protein–protein interaction inhibitors using ligand-directed fragment ligation. Chemical Science. ISSN 2041-6520

Hesketh, E, Tiede, C, Adamson, H et al. (8 more authors) (2019) Affimer reagents as tools in diagnosing plant virus diseases. Scientific Reports, 9. 7524. ISSN 2045-2322

Hughes, DJ, Tiede, C, Penswick, N et al. (12 more authors) (2017) Generation of specific inhibitors of SUMO-1– and SUMO-2/3–mediated protein-protein interactions using Affimer (Adhiron) technology. Science Signaling, 10 (505). eaaj2005. ISSN 1945-0877

Hunter, T, Bonetta, R, Sacco, A et al. (8 more authors) (2018) A Single Mutation is Sufficient to Modify the Metal Selectivity and Specificity of a Eukaryotic Manganese Superoxide Dismutase to Encompass Iron. Chemistry - A European Journal, 24 (20). pp. 5303-5308. ISSN 0947-6539


Kearney, KJ, Pechlivani, N, King, R et al. (13 more authors) (2019) Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot and reduce bleeding complications. Blood, 133 (11). pp. 1233-1244. ISSN 0006-4971

King, RJ, Schuett, K, Tiede, C et al. (10 more authors) (2020) Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk. Haematologica. ISSN 0390-6078

Koutsoumpeli, E, Tiede, C, Murray, J et al. (4 more authors) (2017) Antibody mimetics for the detection of small organic compounds using a quartz crystal microbalance. Analytical Chemistry, 89 (5). pp. 3051-3058. ISSN 0003-2700

Kyle, S, James, KAR and McPherson, MJ (2012) Recombinant production of the therapeutic peptide lunasin. Microbial Cell Factories, 11. 28.


Li, S, Gong, X, Mc Nally, CS et al. (7 more authors) (2016) Rapid Preparation of Highly Reliable PDMS Double Emulsion Microfluidic Devices. RSC Advances, 6 (31). pp. 25927-25933.

Li, S, Zeng, M, Gaule, T et al. (2 more authors) (2017) Passive Picoinjection Enables Controlled Crystallization in a Droplet Microfluidic Device. Small, 13 (41). 1702154. ISSN 1613-6810

Lopata, A, Hughes, R, Tiede, C et al. (5 more authors) (2018) Affimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells. Scientific Reports, 8. 6572. ISSN 2045-2322


Martin, HL, Bedford, R, Heseltine, SJ et al. (5 more authors) (2018) Non-immunoglobulin scaffold proteins: Precision tools for studying protein-protein interactions in cancer. New Biotechnology, 45. pp. 28-35. ISSN 1871-6784

Miles, JA, Hobor, F, Trinh, C et al. (12 more authors) (2021) Selective Affimers Recognise the BCL‐2 Family Proteins BCL‐xL and MCL‐1 through Noncanonical Structural Motifs. ChemBioChem, 22 (1). pp. 232-240. ISSN 1439-4227


Prakash, A, Parsons, SJ, Kyle, S et al. (1 more author) (2012) Recombinant production of self-assembling β-structured peptides using SUMO as a fusion partner. Microbial Cell Factories, 11. 92. ISSN 1475-2859


Robinson, JI, Baxter, EW, Owen, RL et al. (13 more authors) (2018) Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action. Proceedings of the National Academy of Sciences, 115 (1). E72-E81. ISSN 0027-8424

Roper, B.W.R., Tiede, C., Abdul-Zani, I. et al. (11 more authors) (2023) “Affimer” synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation. Journal of Biological Chemistry, 299 (11). 105325. ISSN 0021-9258

Ross, JF, Wildsmith, GC, Johnson, M et al. (9 more authors) (2019) Directed Assembly of Homopentameric Cholera Toxin B‑Subunit Proteins into Higher-Order Structures Using Coiled-Coil Appendages. Journal of the American Chemical Society, 141 (13). pp. 5211-5219. ISSN 0002-7863


Sandrin Gauer, J, Duval, C, Xu, RG et al. (6 more authors) (2023) Fibrin-glycoprotein VI interaction increases platelet procoagulant activity and impacts clot structure. Journal of Thrombosis and Haemostasis, 21 (3). pp. 667-681. ISSN 1538-7933

Schlichthaerle, T, Eklund, A, Schueder, F et al. (7 more authors) (2018) Site‐specific labeling of Affimers for DNA‐PAINT microscopy. Angewandte Chemie - International Edition, 57 (34). pp. 11060-11063. ISSN 1433-7851

Selvaraj, M, Yegambaram, K, Todd, EJAA et al. (10 more authors) (2018) The structure of the human respiratory syncytial virus M2-1 protein bound to the interaction domain of the phosphoprotein P defines the orientation of the complex. mBio, 9 (6). e01554-18.

Shamsuddin, SH, Gibson, TD, Tomlinson, DC et al. (3 more authors) (2021) Reagentless Affimer- and antibody-based impedimetric biosensors for CEA-detection using a novel non-conducting polymer. Biosensors and Bioelectronics, 178. 113013. ISSN 0956-5663

Shamsuddin, SH, Jayne, DG, Tomlinson, DC et al. (2 more authors) (2021) Selection and characterisation of Affimers specific for CEA recognition. Scientific Reports, 11 (1). 744. ISSN 2045-2322

Smith, MA, Pirrat, P, Pearson, AR et al. (6 more authors) (2010) Exploring the Roles of the Metal Ions in Escherichia coli Copper Amine Oxidase,. Biochemistry, 49 (6). pp. 1268-1280. ISSN 0006-2960

Srdanović, S, Wolter, M, Trinh, CH et al. (3 more authors) (2022) Understanding the interaction of 14-3-3 proteins with hDMX and hDM2: a structural and biophysical study. The FEBS Journal, 289 (17). pp. 5341-5358. ISSN 1742-464X

Stevenson, SR, Kamisugi, Y, Trinh, CH et al. (15 more authors) (2016) Genetic analysis of Physcomitrella patens identifies ABSCISIC ACID NON-RESPONSIVE, a regulator of ABA responses unique to basal land plants and required for desiccation tolerance. Plant Cell, 28 (6). pp. 1310-1327. ISSN 1040-4651


Tang, AA-S, Tiede, C, Hughes, DJ et al. (2 more authors) (2017) Isolation of isoform-specific binding proteins (Affimers) by phage display using negative selection. Science Signaling, 10 (505). eaan0868. ISSN 1945-0877

Tanner, S, Ariza, A, Richard, CA et al. (12 more authors) (2014) Crystal structure of the essential transcription antiterminator M2-1 protein of human respiratory syncytial virus and implications of its phosphorylation. Proceedings of the National Academy of Sciences, 111 (4). pp. 1580-1585. ISSN 0027-8424

Thangsunan, P, Lal, N, Tiede, C et al. (8 more authors) (2021) Affimer-based impedimetric biosensors for fibroblast growth factor receptor 3 (FGFR3): a novel tool for detection and surveillance of recurrent bladder cancer. Sensors and Actuators B: Chemical, 326. 128829. ISSN 0925-4005

Tiede, C, Bedford, R, Heseltine, SJ et al. (43 more authors) (2017) Affimer proteins are versatile and renewable affinity reagents. eLife, 6. e24903. ISSN 2050-084X

Tiede, C, Tang, AA, Deacon, SE et al. (8 more authors) (2014) Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications. Protein Engineering, Design and Selection, 27 (5). pp. 145-155. ISSN 1741-0126

Timms, N, Windle, CL, Polyakova, A et al. (5 more authors) (2013) Structural Insights into the Recovery of Aldolase Activity in N -Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with γ-Thialysine by Using a Chemical Mutagenesis Strategy. ChemBioChem, 14 (4). pp. 474-481. ISSN 1439-4227

Troshin, PV, Postis, VLG, Ashworth, D et al. (3 more authors) (2011) PIMS sequencing extension: a laboratory information management system for DNA sequencing facilities. BMC Research Notes, 4. 48. ISSN 1756-0500

Turner, LD, Trinh, CH, Hubball, RA et al. (5 more authors) (2022) From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. Journal of Medicinal Chemistry, 65 (2). pp. 1481-1504. ISSN 0022-2623


Ullah, R, Shehzad, A, Shah, MA et al. (6 more authors) (2020) C-Terminal Domain of the Human Zinc Transporter hZnT8 Is Structurally Indistinguishable from Its Disease Risk Variant (R325W). International Journal of Molecular Sciences, 21 (3). 926. ISSN 1661-6596


Wang, W, Kong, Y, Jiang, J et al. (8 more authors) (2020) Photon induced quantum yield regeneration of cap-exchanged CdSe/CdS quantum rods for ratiometric biosensing and cellular imaging. Nanoscale. ISSN 2040-3364

Wang, W, Guo, Y, Tiede, C et al. (8 more authors) (2017) Ultraefficient Cap-Exchange Protocol To Compact Biofunctional Quantum Dots for Sensitive Ratiometric Biosensing and Cell Imaging. ACS Applied Materials and Interfaces, 9 (18). pp. 15232-15244. ISSN 1944-8244

Windle, CL, Simmons, KJ, Ault, JR et al. (4 more authors) (2017) Extending enzyme molecular recognition with an expanded amino acid alphabet. Proceedings of the National Academy of Sciences, 114 (10). pp. 2610-2615. ISSN 1091-6490


Xie, C, Tiede, C, Zhang, X et al. (6 more authors) (2017) Development of an Affimer-antibody combined immunological diagnosis kit for glypican-3. Scientific Reports, 7 (1). 9608. p. 9608. ISSN 2045-2322


Yuzugullu Karakus, Y, Goc, G, Balci, S et al. (4 more authors) (2018) Identification of the site of oxidase substrate binding in Scytalidium thermophilum catalase. Acta crystallographica. Section D, Structural biology, 74 (Pt 10). pp. 979-985. ISSN 2059-7983


Zhurauski, P, Arya, SK, Jolly, P et al. (4 more authors) (2018) Sensitive and selective Affimer-functionalised interdigitated electrode-based capacitive biosensor for Her4 protein tumour biomarker detection. Biosensors and Bioelectronics, 108. pp. 1-8. ISSN 0956-5663


Álvarez-Rodríguez, B, Tiede, C, Hoste, ACR et al. (11 more authors) (2020) Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric diagnostic tests. PLOS Neglected Tropical Diseases, 14 (6). e0008364. ISSN 1935-2727

This list was generated on Wed Feb 21 04:09:43 2024 GMT.