Browse by Academic Unit (A-Z)

B

Batchelor, M orcid.org/0000-0001-6338-5698, Wolny, M, Baker, EG et al. (3 more authors) (2019) Dynamic ion pair behavior stabilizes single alpha helices in proteins. Journal of Biological Chemistry, 294 (9). pp. 3219-3234. ISSN 0021-9258

Bate, N, Caves, RE, Skinner, SP orcid.org/0000-0002-9349-6935 et al. (4 more authors) (2018) A Novel Mechanism for Calmodulin Dependent Inactivation of Transient Receptor Potential Vanilloid 6. Biochemistry, 57 (18). pp. 2611-2622. ISSN 0006-2960

Bunney, TD, Inglis, AJ, Sanfelice, D et al. (9 more authors) (2018) Disease variants of FGFR3 reveal molecular basis for the recognition and new roles for Cdc37 in Hsp90 chaperone system. Structure, 26 (3). pp. 446-458. ISSN 0969-2126

Burslem, G, Kyle, H, Breeze, AL orcid.org/0000-0001-9723-3350 et al. (4 more authors) (2016) Towards “Bionic” Proteins: Replacement of Continuous Sequences from HIF-1α with Proteomimetics to Create Functional p300 Binding HIF-1α Mimics. Chemical Communications, 52 (31). pp. 5421-5424. ISSN 1359-7345

C

Chai, G, Webb, A, Li, C et al. (34 more authors) (2021) Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron, 109 (2). pp. 241-256. ISSN 0896-6273

D

Drulyte, I orcid.org/0000-0003-1117-7699, Obajdin, J, Trinh, CH et al. (4 more authors) (2019) Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase. IUCrJ, 6 (6). pp. 1120-1133. ISSN 2052-2525

F

Farrell, B orcid.org/0000-0001-9919-9141 and Breeze, A orcid.org/0000-0001-9723-3350 (2018) Structure, activation and dysregulation of fibroblast growth factor receptor kinases: perspectives for clinical targeting. Biochemical Society Transactions, 46 (6). pp. 1753-1770. ISSN 0300-5127

Foster, TL, Thompson, GS, Kalverda, AP et al. (13 more authors) (2014) Structure-guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion release. Hepatology, 59 (2). pp. 408-422. ISSN 0270-9139

H

Henrique dos Santos Rodrigues, F, Firczuk, H, Breeze, A orcid.org/0000-0001-9723-3350 et al. (5 more authors) (2019) The Leishmania PABP1–eIF4E4 interface: a novel 5′–3′ interaction architecture for trans-spliced mRNAs. Nucleic Acids Research, 47 (3). pp. 1493-1504. ISSN 0305-1048

Hewitt, SH, Filby, MH, Hayes, E et al. (4 more authors) (2017) Protein surface mimetics: understanding how ruthenium tris(bipyridines) interact with proteins. ChemBioChem, 18 (2). pp. 223-231. ISSN 1439-7633

K

Karamanos, TK, Jackson, MP, Calabrese, AN et al. (6 more authors) (2019) Structural mapping of oligomeric intermediates in an amyloid assembly pathway. eLife, 8. e46574. ISSN 2050-084X

Karamanos, TK, Kalverda, AP, Thompson, GS et al. (1 more author) (2014) Visualization of transient protein-protein interactions that promote or inhibit amyloid assembly. Molecular Cell, 55 (2). pp. 214-226. ISSN 1097-2765

Karamanos, TK, Pashley, CL, Kalverda, AP et al. (4 more authors) (2016) A population shift between sparsely populated folding intermediates determines amyloidogenicity. Journal of the American Chemical Society, 138 (19). pp. 6271-6280. ISSN 0002-7863

Karamanos, TK orcid.org/0000-0003-2297-540X, Kalverda, AP and Radford, SE orcid.org/0000-0002-3079-8039 (2022) Generating Ensembles of Dynamic Misfolding Proteins. Frontiers in Neuroscience, 16. 881534. ISSN 1662-453X

Kumar, A, Kuhn, LT and Balbach, J (2018) A Cu2+ complex induces the aggregation of human papillomavirus oncoprotein E6 and stabilizes p53. The FEBS journal. ISSN 1742-464X

L

Lescanne, M, Skinner, SP orcid.org/0000-0002-9349-6935, Blok, A et al. (5 more authors) (2017) Methyl group assignment using pseudocontact shifts with PARAssign. Journal of Biomolecular NMR, 69 (4). pp. 183-195. ISSN 0925-2738

M

Ma, J, McLeod, S, Maccormack, K et al. (4 more authors) (2014) Real‐Time Monitoring of New Delhi Metallo‐β‐Lactamase Activity in Living Bacterial Cells by ¹H NMR Spectroscopy. Angewandte Chemie International Edition, 53 (8). pp. 2130-2133. ISSN 1433-7851

Maya-Martinez, R, Xu, Y, Guthertz, N et al. (5 more authors) (2022) Dimers of D76N-β₂-microglobulin display potent antiamyloid aggregation activity. Journal of Biological Chemistry, 298 (12). 102659. ISSN 0021-9258

Monteiro, DCF, Patel, V, Bartlett, CP et al. (9 more authors) (2015) The Structure of the PanD/PanZ Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A. Chemistry and Biology, 22 (4). pp. 492-503. ISSN 1074-5521

P

Pandya, MJ, Schiffers, S, Hounslow, AM et al. (2 more authors) (2018) Why the energy landscape of barnase is hierarchical. Frontiers in Molecular Biosciences, 5. 115.

S

Sanfelice, D, Koss, H, Bunney, TD et al. (4 more authors) (2018) NMR backbone assignments of the tyrosine kinase domain of human fibroblast growth factor receptor 3 in apo state and in complex with inhibitor PD173074. Biomolecular NMR Assignments, 12 (2). pp. 231-235. ISSN 1874-2718

Schnieders, R, Richter, C, Warhaut, S et al. (10 more authors) (2017) Evaluation of (15)N-detected H-N correlation experiments on increasingly large RNAs. Journal of Biomolecular NMR, 69 (1). pp. 31-44. ISSN 1573-5001

Skinner, SP orcid.org/0000-0002-9349-6935, Fogh, RH, Boucher, W et al. (3 more authors) (2016) CcpNmr AnalysisAssign: a flexible platform for integrated NMR analysis. Journal of Biomolecular NMR, 66 (2). pp. 111-124. ISSN 0925-2738

T

Teixeira, JMC, Skinner, SP orcid.org/0000-0002-9349-6935, Arbesú, M et al. (2 more authors) (2018) Farseer-NMR: automatic treatment, analysis and plotting of large, multi-variable NMR data. Journal of Biomolecular NMR, 71 (1). pp. 1-9. ISSN 0925-2738

Tomlinson, JH, Kalverda, AP and Calabrese, AN (2020) Fusidic acid resistance through changes in the dynamics of the drug target. Proceedings of the National Academy of Sciences (PNAS), 117 (41). pp. 25523-25531. ISSN 0027-8424

X

Xu, Y, Maya-Martinez, R, Guthertz, N et al. (6 more authors) (2022) Tuning the rate of aggregation of hIAPP into amyloid using smallmolecule modulators of assembly. Nature Communications, 13. 1040. ISSN 2041-1723

Z

Zacharchenko, T, Kalverda, AP and Wright, SC orcid.org/0000-0002-3509-7506 (2021) Structural basis of Apt48 inhibition of the BCL6 BTB domain. Structure. ISSN 0969-2126