Items where Funder is LISTER INSTITUTE OF PREVENTATIVE MEDICINE.

103844/Z/14/Z

Atteya, R., Ashour, M.E., Ibrahim, E.E. et al. (2 more authors) (2017) Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin. Mechanisms of Ageing and Development, 161 (A). pp. 141-148. ISSN 0047-6374

Meisenberg, C., Ashour, M.E., El-Shafie, L. et al. (7 more authors) (2017) Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan. Nucleic Acids Research, 45 (3). pp. 1159-1176. ISSN 0305-1048

Shawky, S.M., Awad, A.M., Allam, W. et al. (2 more authors) (2016) Gold aggregating gold: A novel nanoparticle biosensor approach for the direct quantification of hepatitis C virus RNA in clinical samples. Biosensors and Bioelectronics. ISSN 0956-5663

Elsayed, W., El-Shafie, L., Hassan, M.K. et al. (2 more authors) (2016) Isoeugenol is a selective potentiator of camptothecin cytotoxicity in vertebrate cells lacking TDP1. Scientific Reports, 6. 26626. ISSN 2045-2322

Mazouzi, A., Stukalov, A., Müller, A.C. et al. (13 more authors) (2016) A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN. Cell Reports, 15 (4). pp. 893-908. ISSN 2211-1247

Walker, C. and El-Khamisy, S.F. orcid.org/0000-0003-2721-7763 (2018) Perturbed autophagy and DNA repair converge to promote neurodegeneration in amyotrophic lateral sclerosis and dementia. Brain, 141 (5). pp. 1247-1262. ISSN 0006-8950

Fielden, J., Wiseman, K., Torrecilla, I. et al. (14 more authors) (2020) TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts. Nature Communications, 11 (1). 1274. ISSN 2041-1723

Herranz-Martin, S., Chandran, J. orcid.org/0000-0002-3486-8583, Lewis, K. et al. (12 more authors) (2017) Viral delivery of C9ORF72 hexanucleotide repeat expansions in mice lead to repeat length dependent neuropathology and behavioral deficits. Disease Models and Mechanisms. ISSN 1754-8403

Southam, H.M., Smith, T.W., Lyon, R.L. et al. (10 more authors) (2018) A thiol-reactive Ru(II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3. Redox Biology, 18. pp. 114-123.

Zaksauskaite, R., Thomas, R.C., van Eeden, F. et al. (1 more author) (2021) Tdp1 protects from topoisomerase 1–mediated chromosomal breaks in adult zebrafish but is dispensable during larval development. Science Advances, 7 (5). eabc4165. ISSN 2375-2548

Ashour, M.E., Allam, W., Elsayed, W. et al. (5 more authors) (2021) High temperature drives topoisomerase mediated chromosomal break repair pathway choice. Cancers, 13 (10). 2315. ISSN 2072-6694

104110/Z/14/A

Carrilero, L., Urwin, L., Ward, E. et al. (5 more authors) (2023) Stringent response-mediated control of GTP homeostasis is required for long-term viability of staphylococcus aureus. Microbiology Spectrum, 11 (2). e00447-23. ISSN 2165-0497

Catley, T.E., Corrigan, R.M. orcid.org/0000-0002-6031-1148 and Parnell, A.J. orcid.org/0000-0001-8606-8644 (2023) Designing effective antimicrobial nanostructured surfaces: highlighting the lack of consensus in the literature. ACS Omega, 8 (17). pp. 14873-14883. ISSN 2470-1343

104110/Z/14/Z

Irving, S.E., Choudhury, N.R. and Corrigan, R.M. orcid.org/0000-0002-6031-1148 (2021) The stringent response and physiological roles of (pp)pGpp in bacteria. Nature Reviews Microbiology, 19 (4). pp. 256-271. ISSN 1740-1526

171964603

Atteya, R., Ashour, M.E., Ibrahim, E.E. et al. (2 more authors) (2017) Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin. Mechanisms of Ageing and Development, 161 (A). pp. 141-148. ISSN 0047-6374

Meisenberg, C., Ashour, M.E., El-Shafie, L. et al. (7 more authors) (2017) Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan. Nucleic Acids Research, 45 (3). pp. 1159-1176. ISSN 0305-1048

Shawky, S.M., Awad, A.M., Allam, W. et al. (2 more authors) (2016) Gold aggregating gold: A novel nanoparticle biosensor approach for the direct quantification of hepatitis C virus RNA in clinical samples. Biosensors and Bioelectronics. ISSN 0956-5663

Elsayed, W., El-Shafie, L., Hassan, M.K. et al. (2 more authors) (2016) Isoeugenol is a selective potentiator of camptothecin cytotoxicity in vertebrate cells lacking TDP1. Scientific Reports, 6. 26626. ISSN 2045-2322

A1749

Zaksauskaite, R., Thomas, R.C., van Eeden, F. et al. (1 more author) (2021) Tdp1 protects from topoisomerase 1–mediated chromosomal breaks in adult zebrafish but is dispensable during larval development. Science Advances, 7 (5). eabc4165. ISSN 2375-2548

BB/R015457/1

Zaksauskaite, R., Thomas, R.C., van Eeden, F. et al. (1 more author) (2021) Tdp1 protects from topoisomerase 1–mediated chromosomal breaks in adult zebrafish but is dispensable during larval development. Science Advances, 7 (5). eabc4165. ISSN 2375-2548

IND/CONT/9/16-17/102

Ashour, M.E., Allam, W., Elsayed, W. et al. (5 more authors) (2021) High temperature drives topoisomerase mediated chromosomal break repair pathway choice. Cancers, 13 (10). 2315. ISSN 2072-6694

NONE

Atteya, R., Ashour, M.E., Ibrahim, E.E. et al. (2 more authors) (2017) Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin. Mechanisms of Ageing and Development, 161 (A). pp. 141-148. ISSN 0047-6374

Meisenberg, C., Ashour, M.E., El-Shafie, L. et al. (7 more authors) (2017) Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan. Nucleic Acids Research, 45 (3). pp. 1159-1176. ISSN 0305-1048

Shawky, S.M., Awad, A.M., Allam, W. et al. (2 more authors) (2016) Gold aggregating gold: A novel nanoparticle biosensor approach for the direct quantification of hepatitis C virus RNA in clinical samples. Biosensors and Bioelectronics. ISSN 0956-5663

Elsayed, W., El-Shafie, L., Hassan, M.K. et al. (2 more authors) (2016) Isoeugenol is a selective potentiator of camptothecin cytotoxicity in vertebrate cells lacking TDP1. Scientific Reports, 6. 26626. ISSN 2045-2322

Mazouzi, A., Stukalov, A., Müller, A.C. et al. (13 more authors) (2016) A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN. Cell Reports, 15 (4). pp. 893-908. ISSN 2211-1247

Walker, C. and El-Khamisy, S.F. orcid.org/0000-0003-2721-7763 (2018) Perturbed autophagy and DNA repair converge to promote neurodegeneration in amyotrophic lateral sclerosis and dementia. Brain, 141 (5). pp. 1247-1262. ISSN 0006-8950

Fielden, J., Wiseman, K., Torrecilla, I. et al. (14 more authors) (2020) TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts. Nature Communications, 11 (1). 1274. ISSN 2041-1723

Herranz-Martin, S., Chandran, J. orcid.org/0000-0002-3486-8583, Lewis, K. et al. (12 more authors) (2017) Viral delivery of C9ORF72 hexanucleotide repeat expansions in mice lead to repeat length dependent neuropathology and behavioral deficits. Disease Models and Mechanisms. ISSN 1754-8403

Southam, H.M., Smith, T.W., Lyon, R.L. et al. (10 more authors) (2018) A thiol-reactive Ru(II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3. Redox Biology, 18. pp. 114-123.

Zaksauskaite, R., Thomas, R.C., van Eeden, F. et al. (1 more author) (2021) Tdp1 protects from topoisomerase 1–mediated chromosomal breaks in adult zebrafish but is dispensable during larval development. Science Advances, 7 (5). eabc4165. ISSN 2375-2548

Ashour, M.E., Allam, W., Elsayed, W. et al. (5 more authors) (2021) High temperature drives topoisomerase mediated chromosomal break repair pathway choice. Cancers, 13 (10). 2315. ISSN 2072-6694

nan

Carrilero, L., Urwin, L., Ward, E. et al. (5 more authors) (2023) Stringent response-mediated control of GTP homeostasis is required for long-term viability of staphylococcus aureus. Microbiology Spectrum, 11 (2). e00447-23. ISSN 2165-0497

Catley, T.E., Corrigan, R.M. orcid.org/0000-0002-6031-1148 and Parnell, A.J. orcid.org/0000-0001-8606-8644 (2023) Designing effective antimicrobial nanostructured surfaces: highlighting the lack of consensus in the literature. ACS Omega, 8 (17). pp. 14873-14883. ISSN 2470-1343

Irving, S.E., Choudhury, N.R. and Corrigan, R.M. orcid.org/0000-0002-6031-1148 (2021) The stringent response and physiological roles of (pp)pGpp in bacteria. Nature Reviews Microbiology, 19 (4). pp. 256-271. ISSN 1740-1526