Dondas, HA, Fishwick, CWG orcid.org/0000-0003-1283-2181, Grigg, RE et al. (1 more author) (2004) 1, 3-Dipolar cycloaddition of stabilised and non-stabilised azomethine ylides derived from uracil polyoxin C (UPoC): access to nikkomycin anologues. Tetrahedron, 60 (15). pp. 3473-3485. ISSN 0040-4020
Abstract
Cascade thermal and decarboxylative cycloaddition reactions of uracil polyoxin C (UPoC) with mono- and di-carbonyl compounds in the presence of a dipolarophile leads, via stabilised and non-stabilised azomethine ylides respectively, to a series of polyoxin cycloadducts related to Nikkomycin B in good to excellent yields and high diastereoselectivity.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Keywords: | Uracil polyoxin C; Nikkomycin; Azomethine ylide; 1,3-Dipolar cycloaddition; Chitin synthetase inhibitors; Decarboxylative cycloaddition; Semi-empirical; Calculations |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 27 Feb 2020 12:12 |
Last Modified: | 30 Jun 2020 14:50 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.tet.2004.02.028 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:99911 |
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