Fazeli, A. orcid.org/0000-0003-0870-9914 and Holt, W.V. (2016) Cross talk during the periconception period. Theriogenology, 86 (1). pp. 438-442. ISSN 0093-691X
Abstract
The cross talk between gametes, embryos, and female reproductive tract plays a crucial role in fine tuning of different reproductive events as well as influencing the epigenetic profile of offspring and their health in adulthood. Here, we describe some background to the recent investigations leading to the discovery of this cross talk. We will also point to important requirements for understanding the maternal communication with gametes and embryos. Finally, we mention two probable hypotheses regarding how gametes and embryos are recognized by the female reproductive tract. It is clear that understanding this cross talk is leading to the production of new means for increasing fertility and potentials for affecting the epigenomic profile of an individual.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2016 Elsevier Inc. This is an author produced version of a paper subsequently published in Theriogenology. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Embryo; Fallopian tube; Oocyte; Oviduct; Periconception; Spermatozoa |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Human Metabolism (Sheffield) |
Funding Information: | Funder Grant number COST OFFICE COST ACTION - FA1201 GENUS PLC NONE EUROPEAN SCIENCE FOUNDATION COST - FA0702-1 SYGEN INTERNATIONAL PLC UNSPECIFIED ZOOLOGICAL SOCIETY OF LONDON none ROYAL VETERINARY COLLEGE CSA6629/LK0661 WELLCOME TRUST (THE) Cond/10/00 EUROPEAN COMMISSION - FP6/FP7 MACE 236708 BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL (BBSRC) BB/FOF/PF/07/08 EUROPEAN COMMISSION - FP6/FP7 RIIFERT - 253948 EUROPEAN COMMISSION - HORIZON 2020 692299 |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 18 May 2016 08:37 |
Last Modified: | 24 Apr 2017 00:18 |
Published Version: | http://dx.doi.org/10.1016/j.theriogenology.2016.04... |
Status: | Published |
Publisher: | Elsevier |
Refereed: | Yes |
Identification Number: | 10.1016/j.theriogenology.2016.04.059 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:99663 |