Colomer, I orcid.org/0000-0003-3886-363X, Empson, CJ orcid.org/0000-0002-4808-8561, Craven, P orcid.org/0000-0002-7617-132X et al. (5 more authors) (2016) A Divergent Synthetic Approach to Diverse Molecular Scaffolds: Assessment of Lead-Likeness using LLAMA, an Open-Access Computational Tool. Chemical Communications, 52 (45). pp. 7209-7212. ISSN 1359-7345
Abstract
Complementary cyclisation reactions of hex-2-ene-1,6-diamine derivatives were exploited in the synthesis of alternative molecular scaffolds. The value of the synthetic approach was analysed using LLAMA, an open-access computational tool for assessing the lead-likeness and novelty of molecular scaffolds.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2016, Royal Society of Chemistry. This is an open access article licensed under a Creative Commons Attribution 3.0 Unported Licence. |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 05 May 2016 09:18 |
Last Modified: | 13 May 2019 15:42 |
Published Version: | http://dx.doi.org/10.1039/C6CC03244C |
Status: | Published |
Publisher: | Royal Society of Chemistry |
Identification Number: | 10.1039/C6CC03244C |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:99287 |