Colomer, I orcid.org/0000-0003-3886-363X, Empson, CJ orcid.org/0000-0002-4808-8561, Craven, P orcid.org/0000-0002-7617-132X et al. (5 more authors) (2016) A Divergent Synthetic Approach to Diverse Molecular Scaffolds: Assessment of Lead-Likeness using LLAMA, an Open-Access Computational Tool. Chemical Communications, 52 (45). pp. 7209-7212. ISSN 1359-7345
Abstract
Complementary cyclisation reactions of hex-2-ene-1,6-diamine derivatives were exploited in the synthesis of alternative molecular scaffolds. The value of the synthetic approach was analysed using LLAMA, an open-access computational tool for assessing the lead-likeness and novelty of molecular scaffolds.
Metadata
| Item Type: | Article | 
|---|---|
| Authors/Creators: | 
 | 
| Copyright, Publisher and Additional Information: | © 2016, Royal Society of Chemistry. This is an open access article licensed under a Creative Commons Attribution 3.0 Unported Licence. | 
| Dates: | 
 | 
| Institution: | The University of Leeds | 
| Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds) | 
| Depositing User: | Symplectic Publications | 
| Date Deposited: | 05 May 2016 09:18 | 
| Last Modified: | 13 May 2019 15:42 | 
| Published Version: | http://dx.doi.org/10.1039/C6CC03244C | 
| Status: | Published | 
| Publisher: | Royal Society of Chemistry | 
| Identification Number: | 10.1039/C6CC03244C | 
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:99287 | 

 CORE (COnnecting REpositories)
 CORE (COnnecting REpositories) CORE (COnnecting REpositories)
 CORE (COnnecting REpositories)