Heymann, D. orcid.org/0000-0001-7777-0669 (2006) Autophagy: A protective mechanism in response to stress and inflammation. Current Opinion in Investigational Drugs, 7 (5). pp. 443-450. ISSN 1472-4472
Abstract
Autophagy is one of the intracellular systems responsible of protein trafficking (degradation/recycling) in eukaryotic cells. Whereas this ubiquitous process contributes to the cytosolic homeostasis, its deregulation is often associated to various pathologies (neurodegenerative diseases, cancer, pathologies with altered inflammatory response, etc.). The present paper gives an overview of autophagy, especially in inflammation, including mechanisms, regulation, functions and future therapies.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2006 The Publisher. |
Keywords: | autophagy; cancer; cell death; drugs; infectious diseases; inflammation |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology and Metabolism (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 14 Apr 2016 15:48 |
Last Modified: | 01 May 2016 09:53 |
Status: | Published |
Publisher: | Thomson Reuters |
Refereed: | Yes |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:98260 |