Sidhu, P.S., McAlindon, M.E. orcid.org/0000-0003-0985-3643, Drew, K. et al. (1 more author) (2015) The Utility of Capsule Endoscopy in Patients under 50 Years of Age with Recurrent Iron Deficiency Anaemia: Is the Juice Worth the Squeeze? Gastroenterology Research and Practice, 2015. 948574. ISSN 1687-6121
Abstract
Background and Aims. The role of capsule endoscopy (CE) in the <50 years of age patients with iron deficiency anaemia (IDA) remains unclear. We aim to assess its utility in this cohort. Methods. All patients referred for CE for recurrent IDA were included retrospectively. Patients were divided into Group 1 (<50 years) and Group 2 (≥50 years). Results. There were 971 patients with recurrent IDA and 28% belonged to Group 1. The mean age was 40 years in this group with a DY of 28% (). Significant diagnoses included erosions and ulcers (26%; ), small bowel (SB) angioectasia (AE) (10%; ), SB tumours (3%; ), Crohn’s disease (3%; ), SB bowel strictures (1%; ), and SB varices (1%; ). On logistic regression, the presence of diabetes () and the use of warfarin () was associated with increased DY. The DY in Group 2 was 38% which was significantly higher than in Group 1 (). While SB tumours were equally common in both groups, AE was commoner in Group 2 (). Conclusion. A significant proportion of patients <50 years are referred for CE. Although the DY is lower compared to those ≥50 years, significant pathology is found in this age group. CE is advisable in patients <50 years old with recurrent IDA and negative bidirectional endoscopies.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | Copyright © 2015 Prabhjot Singh Sidhu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) The University of Sheffield > Sheffield Teaching Hospitals |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 14 Apr 2016 10:36 |
Last Modified: | 14 Apr 2016 10:36 |
Published Version: | http://dx.doi.org/10.1155/2015/948574 |
Status: | Published |
Publisher: | Hindawi Publishing Corporation |
Refereed: | Yes |
Identification Number: | 10.1155/2015/948574 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:98041 |