Williams-Nguyen, Jessica, Brett Sallach, J. orcid.org/0000-0003-4588-3364, Bartelt-Hunt, Shannon et al. (6 more authors) (2016) Antibiotics and antibiotic resistance in agroecosystems:State of the science. Journal of environmental quality. pp. 394-406. ISSN 0047-2425
Abstract
We propose a simple causal model depicting relationships involved in dissemination of antibiotics and antibiotic resistance in agroecosystems and potential effects on human health, functioning of natural ecosystems, and agricultural productivity. Available evidence for each causal link is briefly summarized, and key knowledge gaps are highlighted. A lack of quantitative estimates of human exposure to environmental bacteria, in general, and antibiotic-resistant bacteria, specifically, is a significant data gap hindering the assessment of effects on human health. The contribution of horizontal gene transfer to resistance in the environment and conditions that might foster the horizontal transfer of antibiotic resistance genes into human pathogens also need further research. Existing research has focused heavily on human health effects, with relatively little known about the effects of antibiotics and antibiotic resistance on natural and agricultural ecosystems. The proposed causal model is used to elucidate gaps in knowledge that must be addressed by the research community and may provide a useful starting point for the design and analysis of future research efforts.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York The University of York > Faculty of Sciences (York) > Environment and Geography (York) |
Depositing User: | Pure (York) |
Date Deposited: | 29 Mar 2016 09:34 |
Last Modified: | 16 Oct 2024 12:54 |
Published Version: | https://doi.org/10.2134/jeq2015.07.0336 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.2134/jeq2015.07.0336 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:97227 |