Mewar, D., Marinou, I., Timms, J.M. et al. (2 more authors) (2005) Polymorphism within the telomeric MHC and expression of rheumatoid arthritis candidate genes. In: 25th European Workshop for Rheumatology Research, 24-27 Feb 2005, Glasgow, UK.
Abstract
Several recent studies have indicated a second susceptibility locus for rheumatoid arthritis (RA) in the telomeric MHC close to the tumour necrosis factor locus, a region containing a number of genes of unknown function including HLA-B associated transcripts 1 and 2 (BAT1 and BAT2) and lymphotoxin alpha (LTA). Several single-nucleotide polymorphisms have been described in this region; however, the influence of each on susceptibility is not known. In this study we sought to examine the association of individual single-nucleotide polymorphisms with expression of each mRNA transcript in response to an inflammatory stimulus.
Metadata
Item Type: | Conference or Workshop Item |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2005 BioMed Central Ltd |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) > Division of Genomic Medicine (Sheffield) |
Depositing User: | Sheffield Import |
Date Deposited: | 09 Oct 2009 09:37 |
Last Modified: | 19 Dec 2022 13:23 |
Published Version: | http://dx.doi.org/10.1186/ar1650 |
Status: | Published |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:9706 |