Antibiotic prophylaxis of endocarditis: a NICE mess

Abstract

NICE guidance written in 2008, and revised in 2015, no longer recommends antibiotic prophylaxis in patients at high-risk of infective endocarditis who are undergoing high-risk dental procedures. This guidance is different from every international guideline, including a 2015 European Society of Cardiology revision. The European guideline committee considered, but rejected, the NICE view. How has this important difference in advice arisen and what are its implications?

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Item Type:	Article
Authors/Creators:	Chambers, J.B. Thornhill, M. https://orcid.org/0000-0003-0681-4083 Shanson, D. Prendergast, B.
Copyright, Publisher and Additional Information:	© 2016 Elsevier. This is an author produced version of a paper subsequently published in Lancet Infectious Diseases. Uploaded in accordance with the publisher's self-archiving policy.
Dates:	Published: 1 March 2016
Institution:	The University of Sheffield
Academic Units:	The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Clinical Dentistry (Sheffield)
Depositing User:	Symplectic Sheffield
Date Deposited:	08 Aug 2016 13:14
Last Modified:	16 Nov 2016 08:11
Status:	Published
Publisher:	Elsevier
Refereed:	Yes
Related URLs:	Author
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:96643

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Antibiotic prophylaxis of endocarditis: a NICE mess

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