Examining the origin of selectivity in the reaction of racemic alcohols with chiral N-phosphoryl oxazolidinones
Crook, S., Parr, N.J., Simmons, J. et al. (1 more author)
(2014)
Examining the origin of selectivity in the reaction of racemic alcohols with chiral N-phosphoryl oxazolidinones.
Tetrahedron: Asymmetry, 25 (18-19).
pp. 1298-1308.
ISSN 0957-4166
Abstract
A range of known and novel N-phosphoryl oxazolidinones and imidazolidinones were prepared and screened in the kinetic resolution of a range of racemic magnesium chloroalkoxides. Models are proposed to account for the enantioselectivity achieved based on a combination of chiral relay effects, generation of transient stereochemistry and the structure of the intermediate magnesium alkoxide.
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)