Coates, LC orcid.org/0000-0002-4756-663X, Savage, L, Waxman, R et al. (3 more authors) (2016) Comparison of screening questionnaires to identifypsoriatic arthritis in a primary-care population: across-sectional study. British Journal of Dermatology, 175 (3). pp. 542-548. ISSN 0007-0963
Abstract
Background: many questionnaires are available for assessment of psoriatic arthritis (PsA), but there is little evidence comparing them. Objectives: to test the proposed CONTEST questionnaire, which was developed to identify patients with psoriasis who have undiagnosed PsA, and compare it with the validated Psoriasis Epidemiology Screening Tool (PEST) questionnaire in a primary-care setting. Methods: a random sample of adult patients with psoriasis and no diagnosis of arthritis was identified from five general practice surgeries in Yorkshire, U.K. Consenting patients completed both questionnaires and were assessed by a dermatologist and rheumatologist. Diagnosis of PsA was made by the assessing rheumatologist. Receiver operator characteristic (ROC) curve analysis examined the sensitivity and specificity of potential cut points. Results: in total 932 packs were sent to recruit 191 (20·5%) participants. Of these, 169 (88·5%) were confirmed to have current or previous psoriasis. Using physician diagnosis 17 (10·1%) were found to have previously undiagnosed PsA, while 90 (53·3%) had another musculoskeletal complaint and 62 (36·7%) had no musculoskeletal problems. Using ROC curve analysis, all of the questionnaires showed a significant ability to identify PsA. The area under the curve (AUC) for the CONTEST questionnaires was slightly higher than that of PEST (0·69 and 0·70 vs. 0·65), but there was no significant difference identified. Examining the sensitivities and specificities for the different cut points suggested that a PEST score ≥ 2 would perform better in this dataset, and the optimal scores for CONTEST and CONTEST plus joint manikin were 3 and 4, respectively. Conclusions: the accuracy of the questionnaires to identify PsA appeared similar, with a slightly higher AUC for the CONTEST questionnaires. The optimal cut points in this study appeared lower than in previous studies.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | (c) 2016, British Association of Dermatologists. This is the peer reviewed version of the following article: Coates, LC , Savage, L, Waxman, R, Moverley, AR, Worthington, S and Helliwell, PS (2016) Comparison of screening questionnaires to identifypsoriatic arthritis in a primary-care population: across-sectional study. British Journal of Dermatology. ISSN 0007-0963, which has been published in final form at http://dx.doi.org/10.1111/bjd.14604. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Clinical Biomechanic & Physical Med (LIRMM) (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Clinical Musculoskeletal Medicine (LIRMM) (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 11 Mar 2016 16:22 |
Last Modified: | 29 Jul 2017 16:03 |
Published Version: | http://dx.doi.org/10.1111/bjd.14604 |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1111/bjd.14604 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:96130 |